Adeyemi O. Adeeyo , Isaac O. Amao , Yvan A.T. Ngandjui , Mercy A. Alabi , Titus A.M. Msagati
{"title":"Metabolic profiling of plant and other natural products: Platforms, applications and quality evaluation","authors":"Adeyemi O. Adeeyo , Isaac O. Amao , Yvan A.T. Ngandjui , Mercy A. Alabi , Titus A.M. Msagati","doi":"10.1016/j.microc.2024.111779","DOIUrl":null,"url":null,"abstract":"<div><div>This review unveils the possibility of metabolomics in natural product study and documents available techniques, strategies, and platforms for metabolite profiling. Metabolomics process flow including experimental designs, sample preparations, data acquisition, mining, and results interpretation are presented. The leveraging of metabolomics for maximizing natural product development and sustainable plant use was explored. The extensive review and presentation of details in metabolomics, lead medicine discoveries and frameworks for quality control, fill important research gaps and expand frontiers of knowledge within the field of study.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111779"},"PeriodicalIF":4.9000,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchemical Journal","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0026265X24018915","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
This review unveils the possibility of metabolomics in natural product study and documents available techniques, strategies, and platforms for metabolite profiling. Metabolomics process flow including experimental designs, sample preparations, data acquisition, mining, and results interpretation are presented. The leveraging of metabolomics for maximizing natural product development and sustainable plant use was explored. The extensive review and presentation of details in metabolomics, lead medicine discoveries and frameworks for quality control, fill important research gaps and expand frontiers of knowledge within the field of study.
期刊介绍：
The Microchemical Journal is a peer reviewed journal devoted to all aspects and phases of analytical chemistry and chemical analysis. The Microchemical Journal publishes articles which are at the forefront of modern analytical chemistry and cover innovations in the techniques to the finest possible limits. This includes fundamental aspects, instrumentation, new developments, innovative and novel methods and applications including environmental and clinical field.
Traditional classical analytical methods such as spectrophotometry and titrimetry as well as established instrumentation methods such as flame and graphite furnace atomic absorption spectrometry, gas chromatography, and modified glassy or carbon electrode electrochemical methods will be considered, provided they show significant improvements and novelty compared to the established methods.
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