Pub Date : 2024-11-15DOI: 10.1016/j.microc.2024.112170
Noorfatimah Yahaya , Nur Nadhirah Mohamad Zain , Ahmad Husaini Mohamed , Grasianto , Sazlinda Kamaruzaman , Mazidatulakmam Miskam , Rajeev Jain , Muggundha Raoov , Wan Nazwanie Wan Abdullah
In this article, we provide an in-depth review of the application of nanosorbents for bioanalytical sample preparation. Based on the reported literature, researchers are increasingly interested in using nanomaterials to enhance conventional sorptive extraction methods and develop innovative techniques in bioanalysis. The properties, advantages, and disadvantages of various classes of nanosorbents used in bioanalytical sample preparation were discussed in this study. Detailed mechanisms of separation, green metrics evaluation, and the challenges and potential of nanosorbents in solid-phase extraction techniques are also elaborated. It is hoped that this review will assist researchers in the development of ideal techniques for selective, fast, green, simple, sensitive, and accurate analytical methodologies for bioanalysis.
{"title":"Nanosorbents in solid-phase extraction techniques for bioanalysis: A review","authors":"Noorfatimah Yahaya , Nur Nadhirah Mohamad Zain , Ahmad Husaini Mohamed , Grasianto , Sazlinda Kamaruzaman , Mazidatulakmam Miskam , Rajeev Jain , Muggundha Raoov , Wan Nazwanie Wan Abdullah","doi":"10.1016/j.microc.2024.112170","DOIUrl":"10.1016/j.microc.2024.112170","url":null,"abstract":"<div><div>In this article, we provide an in-depth review of the application of nanosorbents for bioanalytical sample preparation. Based on the reported literature, researchers are increasingly interested in using nanomaterials to enhance conventional sorptive extraction methods and develop innovative techniques in bioanalysis. The properties, advantages, and disadvantages of various classes of nanosorbents used in bioanalytical sample preparation were discussed in this study. Detailed mechanisms of separation, green metrics evaluation, and the challenges and potential of nanosorbents in solid-phase extraction techniques are also elaborated. It is hoped that this review will assist researchers in the development of ideal techniques for selective, fast, green, simple, sensitive, and accurate analytical methodologies for bioanalysis.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112170"},"PeriodicalIF":4.9,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-13DOI: 10.1016/j.microc.2024.112086
Hany Abd El-Raheem , Rabiaa Helim , Rabeay Y.A. Hassan , Ahmed F.A. Youssef , H. Korri-Youssoufi , Charoenkwan Kraiya
Naturally occurring heavy metals (HMs) present a serious risk to human health and the environment because of their toxicity, persistence, and tendency to bioaccumulate. Their presence in air, water, soil, and food can lead to a multitude of adverse effects, from acute poisoning to chronic health problems. The rapid expansion of industrialization and technology has increased HMs contamination from industrial emissions, mining, agriculture, urbanization, and e-waste, posing serious risks to ecosystems and public health. To tackle this increasing challenge, it is essential to develop highly robust, sensitive, and selective electrochemical detection methods for the rapid identification of heavy metal ions (HMIs) contaminants. This review investigates a variety of electrochemical sensors and biosensors utilizing voltammetric techniques for HMIs detection. It covers voltammetric methods such as cyclic voltammetry (CV), square wave voltammetry (SWV), differential-pulse voltammetry (DPV), normal pulse voltammetry (NPV), staircase voltammetry (SV), linear sweep voltammetry (LSV), hydrodynamic voltammetry (HV), anodic stripping voltammetry (ASV), cathodic stripping voltammetry (CSV), and adsorptive stripping voltammetry (AdSV). The review also emphasizes recent advancements in the electrochemical detection of HMIs through various sensor and biosensor platforms, including different nanomaterials and DNA aptamers. These innovations have potential applications in environmental monitoring, food and water safety, industrial waste management, and public health protection, making them vital tools for safeguarding human health and the environment from HMIs contamination.
天然重金属（HMs）因其毒性、持久性和生物累积倾向，对人类健康和环境构成严重威胁。它们在空气、水、土壤和食物中的存在会导致从急性中毒到慢性健康问题等多种不良影响。工业化和技术的快速发展加剧了工业排放、采矿、农业、城市化和电子垃圾等造成的 HMs 污染，对生态系统和公众健康构成了严重威胁。为应对这一日益严峻的挑战，必须开发高度可靠、灵敏和选择性强的电化学检测方法，以快速识别重金属离子（HMIs）污染物。本综述研究了利用伏安技术检测重金属离子的各种电化学传感器和生物传感器。它涵盖了各种伏安方法，如循环伏安法（CV）、方波伏安法（SWV）、差分脉冲伏安法（DPV）、正常脉冲伏安法（NPV）、阶梯伏安法（SV）、线性扫描伏安法 (LSV)、流体动力伏安法 (HV)、阳极剥离伏安法 (ASV)、阴极剥离伏安法 (CSV) 和吸附剥离伏安法 (AdSV)。综述还强调了通过各种传感器和生物传感器平台（包括不同的纳米材料和 DNA 类似物）对 HMIs 进行电化学检测的最新进展。这些创新技术在环境监测、食品和水安全、工业废物管理和公共卫生保护方面具有潜在的应用前景，是保护人类健康和环境免受 HMIs 污染的重要工具。
{"title":"Electrochemical methods for the detection of heavy metal ions: From sensors to biosensors","authors":"Hany Abd El-Raheem , Rabiaa Helim , Rabeay Y.A. Hassan , Ahmed F.A. Youssef , H. Korri-Youssoufi , Charoenkwan Kraiya","doi":"10.1016/j.microc.2024.112086","DOIUrl":"10.1016/j.microc.2024.112086","url":null,"abstract":"<div><div>Naturally occurring heavy metals (HMs) present a serious risk to human health and the environment because of their toxicity, persistence, and tendency to bioaccumulate. Their presence in air, water, soil, and food can lead to a multitude of adverse effects, from acute poisoning to chronic health problems. The rapid expansion of industrialization and technology has increased HMs contamination from industrial emissions, mining, agriculture, urbanization, and e-waste, posing serious risks to ecosystems and public health. To tackle this increasing challenge, it is essential to develop highly robust, sensitive, and selective electrochemical detection methods for the rapid identification of heavy metal ions (HMIs) contaminants. This review investigates a variety of electrochemical sensors and biosensors utilizing voltammetric techniques for HMIs detection. It covers voltammetric methods such as cyclic voltammetry (CV), square wave voltammetry (SWV), differential-pulse voltammetry (DPV), normal pulse voltammetry (NPV), staircase voltammetry (SV), linear sweep voltammetry (LSV), hydrodynamic voltammetry (HV), anodic stripping voltammetry (ASV), cathodic stripping voltammetry (CSV), and adsorptive stripping voltammetry (AdSV). The review also emphasizes recent advancements in the electrochemical detection of HMIs through various sensor and biosensor platforms, including different nanomaterials and DNA aptamers. These innovations have potential applications in environmental monitoring, food and water safety, industrial waste management, and public health protection, making them vital tools for safeguarding human health and the environment from HMIs contamination.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112086"},"PeriodicalIF":4.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-13DOI: 10.1016/j.microc.2024.112182
M.A. Diab , Heba A. El-Sabban , Kwang-Hyun Baek
Zearalenone (ZEN), a mycotoxin generated by fusarium species, is often found in food and feed and can be extremely harmful to human and animal health. Warranting food safety requires effective extraction of ZEN from contaminated matrices. This mini-review concisely summarizes the most recent ZEN extraction techniques from contaminated food and feed. It highlights firstly various extraction techniques, including liquid–liquid extraction (LLE), solid phase extraction using molecularly imprinted polymers (SPE-MIPs), [Quick, Easy, Cheap, Effective, Rugged, and Safe method (QUEChERS)], green extraction methods such as ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE) to improve extraction approaches. Secondly, it discusses recent advanced methods of ZEN detection. This review also discusses the challenges associated with ZEN extraction such as matrix effects, co-contaminants, and the need for standardization method. It emphasizes the importance of continued research to refine existing techniques and develop novel strategies that ensure high efficiency, specificity, and environmental sustainability.
玉米赤霉烯酮（ZEN）是一种由镰刀菌产生的霉菌毒素，经常出现在食品和饲料中，对人类和动物的健康极为有害。要保证食品安全，就必须从受污染的基质中有效提取玉米赤霉烯酮。本微型综述简明扼要地总结了从受污染的食品和饲料中提取 ZEN 的最新技术。首先，它重点介绍了各种萃取技术，包括液-液萃取（LLE）、使用分子印迹聚合物的固相萃取（SPE-MIPs）、[快速、简便、廉价、有效、坚固和安全的方法（QUEChERS）]、绿色萃取方法（如超声辅助萃取（UAE）和微波辅助萃取（MAE）），以改进萃取方法。其次，它还讨论了最新的 ZEN 检测先进方法。本综述还讨论了与锌萃取相关的挑战，如基质效应、共污染物以及标准化方法的必要性。综述强调了继续开展研究以完善现有技术并开发新型策略的重要性，从而确保高效率、特异性和环境可持续性。
{"title":"Recent advances in zearalenone clean-up approaches from polluted food and feed: A mini-review of the State-of-the-art developments","authors":"M.A. Diab , Heba A. El-Sabban , Kwang-Hyun Baek","doi":"10.1016/j.microc.2024.112182","DOIUrl":"10.1016/j.microc.2024.112182","url":null,"abstract":"<div><div>Zearalenone (ZEN), a mycotoxin generated by fusarium species, is often found in food and feed and can be extremely harmful to human and animal health. Warranting food safety requires effective extraction of ZEN from contaminated matrices. This mini-review concisely summarizes the most recent ZEN extraction techniques from contaminated food and feed. It highlights firstly various extraction techniques, including liquid–liquid extraction (LLE), solid phase extraction using molecularly imprinted polymers (SPE-MIPs), [Quick, Easy, Cheap, Effective, Rugged, and Safe method (QUEChERS)], green extraction methods such as ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE) to improve extraction approaches. Secondly, it discusses recent advanced methods of ZEN detection. This review also discusses the challenges associated with ZEN extraction such as matrix effects, co-contaminants, and the need for standardization method. It emphasizes the importance of continued research to refine existing techniques and develop novel strategies that ensure high efficiency, specificity, and environmental sustainability.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112182"},"PeriodicalIF":4.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-02DOI: 10.1016/j.microc.2024.112072
Mahdi Ghorbani , Ava Saghafi , Nahid Afshar Lahoori , Sara Sarabyar , Parisa Mohammadi , Mojgan Ojaghzadeh Khalil Abad
Phthalate esters (PAEs), ubiquitous plasticizers in diverse consumer products, pose significant environmental and human health risks due to their persistence and endocrine-disrupting properties. Accurately determining PAEs in various environmental matrices is crucial for evaluating exposure levels, assessing risks, and implementing effective mitigation strategies. This review comprehensively examines sample preparation techniques for PAE analysis, focusing on methodologies. We categorize these techniques into traditional methods (solid phase extraction, liquid–liquid extraction, QuEChERS), advanced techniques (liquid phase microextraction, solid phase microextraction, and their modifications), and hybrid approaches combining multiple techniques. The strengths, limitations, and recent advancements of each method are thoroughly discussed. This compilation not only summarizes current knowledge but also highlights emerging trends and research gaps, providing valuable insights for future investigations. By fostering scientific progress and innovation in PAE analysis, we aim to support the development of robust analytical methods that contribute to environmental monitoring and risk assessment, ultimately safeguarding human health and the environment.
邻苯二甲酸酯（PAEs）是各种消费品中无处不在的增塑剂，由于其持久性和干扰内分泌的特性，对环境和人类健康构成了重大风险。准确测定各种环境基质中的 PAEs 对于评估暴露水平、评估风险和实施有效的缓解策略至关重要。本综述全面探讨了 PAE 分析的样品制备技术，重点是方法学。我们将这些技术分为传统方法（固相萃取、液液萃取、QuEChERS）、先进技术（液相微萃取、固相微萃取及其改进）以及多种技术相结合的混合方法。每种方法的优势、局限性和最新进展都有详尽的讨论。这本汇编不仅总结了当前的知识，还强调了新出现的趋势和研究空白，为未来的研究提供了宝贵的见解。通过促进 PAE 分析领域的科学进步和创新，我们旨在支持开发有助于环境监测和风险评估的可靠分析方法，最终保护人类健康和环境。
{"title":"Comprehensive review of sample preparation strategies for phthalate ester analysis in various real samples","authors":"Mahdi Ghorbani , Ava Saghafi , Nahid Afshar Lahoori , Sara Sarabyar , Parisa Mohammadi , Mojgan Ojaghzadeh Khalil Abad","doi":"10.1016/j.microc.2024.112072","DOIUrl":"10.1016/j.microc.2024.112072","url":null,"abstract":"<div><div>Phthalate esters (PAEs), ubiquitous plasticizers in diverse consumer products, pose significant environmental and human health risks due to their persistence and endocrine-disrupting properties. Accurately determining PAEs in various environmental matrices is crucial for evaluating exposure levels, assessing risks, and implementing effective mitigation strategies. This review comprehensively examines sample preparation techniques for PAE analysis, focusing on methodologies. We categorize these techniques into traditional methods (solid phase extraction, liquid–liquid extraction, QuEChERS), advanced techniques (liquid phase microextraction, solid phase microextraction, and their modifications), and hybrid approaches combining multiple techniques. The strengths, limitations, and recent advancements of each method are thoroughly discussed. This compilation not only summarizes current knowledge but also highlights emerging trends and research gaps, providing valuable insights for future investigations. By fostering scientific progress and innovation in PAE analysis, we aim to support the development of robust analytical methods that contribute to environmental monitoring and risk assessment, ultimately safeguarding human health and the environment.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112072"},"PeriodicalIF":4.9,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The imperative of global security amidst persistent threats of terrorism, organized crimes, and accidental events underscores the critical role of explosive detection in safeguarding public safety. While effective, traditional detection methods are often time- and resource-intensive and may not always be suitable for on-site applications in specific scenarios. Consequently, there has been a concerted research effort to develop fluorescent materials with diverse sensing mechanisms to achieve heightened sensitivity, selectivity, and rapid response times in explosive detection. This review explores the exploration of supramolecular systems, including cucurbit[n]uril, pillar [n]arenes, cyclodextrin, calixarenes, electron-rich supramolecules, and related complexes, designed to enhance the efficiency of explosive detection. Recent advancements and emerging technologies in this field are discussed in the review, intending to stimulate further inquiry and innovation in synthesizing and applying supramolecular complexes for explosive detection, addressing the urgent demand for heightened security measures.
{"title":"Supramolecular luminescent sensors for explosive detection: Current trends and future directions","authors":"Abhirami R.B. , Mahesh Vasava , Manaswini Karsharma , Riya Khandelwal , Prasenjit Maity","doi":"10.1016/j.microc.2024.112063","DOIUrl":"10.1016/j.microc.2024.112063","url":null,"abstract":"<div><div>The imperative of global security amidst persistent threats of terrorism, organized crimes, and accidental events underscores the critical role of explosive detection in safeguarding public safety. While effective, traditional detection methods are often time- and resource-intensive and may not always be suitable for on-site applications in specific scenarios. Consequently, there has been a concerted research effort to develop fluorescent materials with diverse sensing mechanisms to achieve heightened sensitivity, selectivity, and rapid response times in explosive detection. This review explores the exploration of supramolecular systems, including cucurbit[n]uril, pillar [n]arenes, cyclodextrin, calixarenes, electron-rich supramolecules, and related complexes, designed to enhance the efficiency of explosive detection. Recent advancements and emerging technologies in this field are discussed in the review, intending to stimulate further inquiry and innovation in synthesizing and applying supramolecular complexes for explosive detection, addressing the urgent demand for heightened security measures.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112063"},"PeriodicalIF":4.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-29DOI: 10.1016/j.microc.2024.112043
Mohd Shoab Ali , Saurav Kumar Jha , Garima Gupta , Amirhossein Sahebkar , Prashant Kesharwani
Scientists are intrigued by the enzyme-like characteristics of nanozymes, which connect nanotechnology and biology. In 2007, nanozyme research exploded with the discovery of enzyme-mimicking magnetic nanoparticles (NPs). Over the last decade, nanozymes have revealed their catalytic secrets and expanded their applications. Biocatalytic tumor treatment uses nanozymes as a tiny enzyme mimics, to treat various cancers. This method combines nanotechnology and enzyme-driven biocatalysis. In addition, novel nanocatalysts usually employ multivalent ions as catalyst centres and are widely reported to outperform enzymes in catalysis. They also have better stability in living organisms, functional versatility, and lower production costs. A recent study suggests that nanozymes for biocatalytic tumor treatment could be promising because malignant tumors can change or alter numerous enzymes. Furthermore, the current research in this domain focuses more on iron-based nanostructures because they are simple to make, biocompatible, have promising physical properties, and can catalyze biological processes efficiently; and largely increase tumor hypoxia and reactive oxygen species (ROS)-mediated damage via ferroptosis. Apart from the above-mentioned properties, nanozymes can increase chromogenic or fluorogenic chemical oxidation with certain analytes. This colour change or fluorescence signal can identify and quantify the target biomarker. This review covers nanozyme research for the medical purposes, including their inherent enzymatic properties, biosensing applications for biomarker detection, and other intriguing potential. We also addressed major issues that might impact their clinical use and future progress.
{"title":"Frontiers of nanozymes: Enhancing cancer diagnosis and therapeutic strategies","authors":"Mohd Shoab Ali , Saurav Kumar Jha , Garima Gupta , Amirhossein Sahebkar , Prashant Kesharwani","doi":"10.1016/j.microc.2024.112043","DOIUrl":"10.1016/j.microc.2024.112043","url":null,"abstract":"<div><div>Scientists are intrigued by the enzyme-like characteristics of nanozymes, which connect nanotechnology and biology. In 2007, nanozyme research exploded with the discovery of enzyme-mimicking magnetic nanoparticles (NPs). Over the last decade, nanozymes have revealed their catalytic secrets and expanded their applications. Biocatalytic tumor treatment uses nanozymes as a tiny enzyme mimics, to treat various cancers. This method combines nanotechnology and enzyme-driven biocatalysis. In addition, novel nanocatalysts usually employ multivalent ions as catalyst centres and are widely reported to outperform enzymes in catalysis. They also have better stability in living organisms, functional versatility, and lower production costs. A recent study suggests that nanozymes for biocatalytic tumor treatment could be promising because malignant tumors can change or alter numerous enzymes. Furthermore, the current research in this domain focuses more on iron-based nanostructures because they are simple to make, biocompatible, have promising physical properties, and can catalyze biological processes efficiently; and largely increase tumor hypoxia and reactive oxygen species (ROS)-mediated damage <em>via</em> ferroptosis. Apart from the above-mentioned properties, nanozymes can increase chromogenic or fluorogenic chemical oxidation with certain analytes. This colour change or fluorescence signal can identify and quantify the target biomarker. This review covers nanozyme research for the medical purposes, including their inherent enzymatic properties, biosensing applications for biomarker detection, and other intriguing potential. We also addressed major issues that might impact their clinical use and future progress.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112043"},"PeriodicalIF":4.9,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-28DOI: 10.1016/j.microc.2024.112011
Arnavaz Keikavousi Behbahan, Iman Al Yahyai, Haider A.J. Al Lawati, Javad Hassenzadeh, FakhrEldin O. Suliman
Paper-based analytical devices (PADs) can be considered as the latest regression of lab-on-a-chip devices and have attracted the attention of many researchers. Recently, noteworthy progress has been made in various fields regarding the introduction of metal–organic frameworks (MOFs). Due to the intrinsic advantages of both PADs and MOFs, there has been a rapid growth in their fields confirmed by the large number of publications and citations. The integration of various MOFs within PADs is anticipated to fabricate state-of-the-art devices for several applications in a wide range of fields. This manuscript aims to review the recent 5 years of published studies based on the coupling of MOFs on PADs, outlining their potential application in different fields. Furthermore, challenges and obstacles as well as prospects related to this combination have been discussed.
纸基分析装置（PAD）可视为片上实验室装置的最新发展，吸引了众多研究人员的关注。最近，各领域在引入金属有机框架（MOFs）方面取得了显著进展。由于 PADs 和 MOFs 本身的优势，它们在各自领域的快速发展得到了大量论文的发表和引用。将各种 MOF 整合到 PAD 中，有望制造出最先进的设备，应用于多个领域。本手稿旨在回顾最近 5 年发表的有关在 PAD 上耦合 MOFs 的研究，概述其在不同领域的潜在应用。此外，还讨论了与这种组合相关的挑战、障碍和前景。
{"title":"Implementation of the metal organic frameworks on paper-based devices: A review on current applications and future sights","authors":"Arnavaz Keikavousi Behbahan, Iman Al Yahyai, Haider A.J. Al Lawati, Javad Hassenzadeh, FakhrEldin O. Suliman","doi":"10.1016/j.microc.2024.112011","DOIUrl":"10.1016/j.microc.2024.112011","url":null,"abstract":"<div><div>Paper-based analytical devices (PADs) can be considered as the latest regression of lab-on-a-chip devices and have attracted the attention of many researchers. Recently, noteworthy progress has been made in various fields regarding the introduction of metal–organic frameworks (MOFs). Due to the intrinsic advantages of both PADs and MOFs, there has been a rapid growth in their fields confirmed by the large number of publications and citations. The integration of various MOFs within PADs is anticipated to fabricate state-of-the-art devices for several applications in a wide range of fields. This manuscript aims to review the recent 5 years of published studies based on the coupling of MOFs on PADs, outlining their potential application in different fields. Furthermore, challenges and obstacles as well as prospects related to this combination have been discussed.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112011"},"PeriodicalIF":4.9,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naturally-occurring mineral substances called clays are available at a low cost and are ecologically beneficial. These clays are composed of two-dimensional (2D) nanoclays, layered silicates made up of platelets with nanoscale thickness joined together by van der Waals forces. There are various types of nanoclays frequently cited in the literature, such as montmorillonite (MMT), kaolinite, vermiculite (VMT), laponite, and illite. These nanoclays possess distinct physical and chemical characteristics, which make them useful for a variety of applications in scientific and industrial fields. This study includes the development of electrochemical sensors that employ modified electrodes with 2D nanoclays and their composites to detect drugs, diagnose medical conditions, monitor environmental pollutants, and ensure food safety. This article discusses these applications in detail. Furthermore, we explored the uses of 2D nanoclays in various electrochemical applications, such as serving as cathodes in Li-sulfur batteries, separators in batteries and supercapacitors, and acting the role of catalysts in the processes of water electrolysis and oxygen reduction reaction. Finally, we assessed the current challenges related to the use of 2D nanoclays in electrochemistry.
{"title":"Recent electrochemical applications of Two-Dimensional nanoclays based materials","authors":"Hadi Beitollahi , Zahra Dourandish , Somayeh Tajik , Peyman Mohammadzadeh Jahani , Reza Zaimbashi , Fariba Garkani Nejad , Sayed Zia Mohammadi","doi":"10.1016/j.microc.2024.111908","DOIUrl":"10.1016/j.microc.2024.111908","url":null,"abstract":"<div><div>Naturally-occurring mineral substances called clays are available at a low cost and are ecologically beneficial. These clays are composed of two-dimensional (2D) nanoclays, layered silicates made up of platelets with nanoscale thickness joined together by van der Waals forces. There are various types of nanoclays frequently cited in the literature, such as montmorillonite (MMT), kaolinite, vermiculite (VMT), laponite, and illite. These nanoclays possess distinct physical and chemical characteristics, which make them useful for a variety of applications in scientific and industrial fields. This study includes the development of electrochemical sensors that employ modified electrodes with 2D nanoclays and their composites to detect drugs, diagnose medical conditions, monitor environmental pollutants, and ensure food safety. This article discusses these applications in detail. Furthermore, we explored the uses of 2D nanoclays in various electrochemical applications, such as serving as cathodes in Li-sulfur batteries, separators in batteries and supercapacitors, and acting the role of catalysts in the processes of water electrolysis and oxygen reduction reaction. Finally, we assessed the current challenges related to the use of 2D nanoclays in electrochemistry.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111908"},"PeriodicalIF":4.9,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pesticides play a crucial role in modern agriculture for managing pests; however, their indiscriminate application raises concerns regarding food safety. It is, therefore, necessary to advance effective and rapid techniques for detecting pesticide residues in food products and water. Gold nanoclusters (AuNCs) are considered a versatile group due to their diverse functionality and attractive optoelectronic and photoluminescence characteristics, indicating significant promise in food safety. Specifically, AuNCs optical biosensors have been featured as universal and versatile tools for manufacturing new-generation recognizing approaches with enhanced sensitivity, stability, and specificity. In this review, we explore the latest tests and tools that utilize optical sensors with AuNCs for detecting pesticides. The review explores the evolution of these sensors and their innovative strategies for attaching recognition elements to AuNCs, both chemically and physically. Additionally, the article explores the synthesis principle, sensing mechanism, and recent advancements in using AuNCs as optical biosensors to detect pesticides. Furthermore, it explores the utilization of optical AuNC probes in ensuring food safety and the obstacles that may arise during their incorporation, drawing from the latest developments in this area.
{"title":"Surface functionalized gold nanoclusters based on optical biosensors for detecting pesticide residues in agricultural foods: A critical review","authors":"Zahra Abbaszadeh , Mir-Michael Mousavi , Mansour mahmoudpour","doi":"10.1016/j.microc.2024.111988","DOIUrl":"10.1016/j.microc.2024.111988","url":null,"abstract":"<div><div>Pesticides play a crucial role in modern agriculture for managing pests; however, their indiscriminate application raises concerns regarding food safety. It is, therefore, necessary to advance effective and rapid techniques for detecting pesticide residues in food products and water. Gold nanoclusters (AuNCs) are considered a versatile group due to their diverse functionality and attractive optoelectronic and photoluminescence characteristics, indicating significant promise in food safety. Specifically, AuNCs optical biosensors have been featured as universal and versatile tools for manufacturing new-generation recognizing approaches with enhanced sensitivity, stability, and specificity. In this review, we explore the latest tests and tools that utilize optical sensors with AuNCs for detecting pesticides. The review explores the evolution of these sensors and their innovative strategies for attaching recognition elements to AuNCs, both chemically and physically. Additionally, the article explores the synthesis principle, sensing mechanism, and recent advancements in using AuNCs as optical biosensors to detect pesticides. Furthermore, it explores the utilization of optical AuNC probes in ensuring food safety and the obstacles that may arise during their incorporation, drawing from the latest developments in this area.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111988"},"PeriodicalIF":4.9,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-21DOI: 10.1016/j.microc.2024.111819
Nutan Shukla , Carol Yazbleydy Cárdenas Rodriguez , Ratnesh Das , Elizaveta Mukhanova , Alexander Soldatov
The development of microfluidic devices represents a major breakthrough in biological research. These devices, referred to as analytical microsystems, are engineered for high sensitivity and are adept at analyzing complex biological materials. This innovation has significantly advanced biotechnology, allowing researchers to perform more accurate and efficient analyses of biological samples.Microfluidic devices function at the micron and nanoscale, utilizing precisely designed micro-channels to separate, analyze, and modify the behaviour of fluids and particles across various applications, including drug development, environmental monitoring, biohazard detection, and clinical diagnostics. The increasing interest in microfluidics has revealed numerous advantages associated with the materials used in this technology. By harnessing the distinct properties of fluids at the micro scale, these devices improve automation, control, and high-throughput processing capabilities, potentially replacing some traditional biological analytical and diagnostic methods.Moreover, microfluidic devices tend to be more cost-effective, require shorter bioassay times, and utilize smaller quantities of chemicals and sample volumes. This makes them a highly efficient solution for advanced research in biotechnology. This review article focuses on the compatibility, benefits, and applications of various materials—both inorganic and organic material fabrication of microfluidic devices. We highlight the enhanced performance of micro/nano channels achieved through hybrid manufacturing techniques that integrate advanced functionalization or modification methods. Additionally, we discuss recent advancements in specific applications of microfluidics, including their integration with Raman spectroscopy, mass spectrometry, and optical detection techniques to enhance biomedical applications and sensing capabilities.
{"title":"Innovative biomedical applications of micro/nano channel technologies in microfluidics","authors":"Nutan Shukla , Carol Yazbleydy Cárdenas Rodriguez , Ratnesh Das , Elizaveta Mukhanova , Alexander Soldatov","doi":"10.1016/j.microc.2024.111819","DOIUrl":"10.1016/j.microc.2024.111819","url":null,"abstract":"<div><div>The development of microfluidic devices represents a major breakthrough in biological research. These devices, referred to as analytical microsystems, are engineered for high sensitivity and are adept at analyzing complex biological materials. This innovation has significantly advanced biotechnology, allowing researchers to perform more accurate and efficient analyses of biological samples.Microfluidic devices function at the micron and nanoscale, utilizing precisely designed micro-channels to separate, analyze, and modify the behaviour of fluids and particles across various applications, including drug development, environmental monitoring, biohazard detection, and clinical diagnostics. The increasing interest in microfluidics has revealed numerous advantages associated with the materials used in this technology. By harnessing the distinct properties of fluids at the micro scale, these devices improve automation, control, and high-throughput processing capabilities, potentially replacing some traditional biological analytical and diagnostic methods.Moreover, microfluidic devices tend to be more cost-effective, require shorter bioassay times, and utilize smaller quantities of chemicals and sample volumes. This makes them a highly efficient solution for advanced research in biotechnology. This review article focuses on the compatibility, benefits, and applications of various materials—both inorganic and organic material fabrication of microfluidic devices. We highlight the enhanced performance of micro/nano channels achieved through hybrid manufacturing techniques that integrate advanced functionalization or modification methods. Additionally, we discuss recent advancements in specific applications of microfluidics, including their integration with Raman spectroscopy, mass spectrometry, and optical detection techniques to enhance biomedical applications and sensing capabilities.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111819"},"PeriodicalIF":4.9,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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