Populations particulières : impact de l’état général et des principales comorbidités et de leurs traitements sur la prise en charge thérapeutique locale des patients présentant un Cancer Bronchique Non à Petites Cellules
Numerous factors, whether linked to cancer or to comorbidities, can affect the Performance Status (PS). PS remains a major independent prognostic factor in lung cancer despite the heterogeneity of cancer patients with poor PS. Lung cancer occurs mainly at an advanced age and is linked in most of the cases to smoking, which can also lead to long-term organ failure. Comorbidities and PS should then be considered to determine the most suited local treatment. The aim of this review is to highlight the impact of PS and certain comorbidities (coronaropathy, cirrhosis, chronic kidney disease and interstitial lung disease) on the management and treatment of localized lung cancer.