Therapeutic interfering particles against HIV: molecular parasites reducing viremia

IF 4.3 2区 化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR Inorganic Chemistry Pub Date : 2024-10-14 DOI:10.1038/s41392-024-02001-0
Henning Gruell, Stanley Odidika, Philipp Schommers
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Abstract

In a recent article in Science, Leon Weinberger and colleagues report on successful proof-of-concept studies of a novel strategy to control HIV-1 infection by using interfering viral particles.1 This approach radically differs from small-molecule antiretroviral drugs that can prevent disease progression and transmission by inhibiting viral replication but require life-long use.

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针对艾滋病毒的治疗干扰颗粒:减少病毒血症的分子寄生虫
莱昂-温伯格及其同事最近在《科学》(Science)杂志上发表文章,报告了一种利用干扰病毒颗粒控制 HIV-1 感染的新策略的概念验证研究取得成功。
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来源期刊
Inorganic Chemistry
Inorganic Chemistry 化学-无机化学与核化学
CiteScore
7.60
自引率
13.00%
发文量
1960
审稿时长
1.9 months
期刊介绍: Inorganic Chemistry publishes fundamental studies in all phases of inorganic chemistry. Coverage includes experimental and theoretical reports on quantitative studies of structure and thermodynamics, kinetics, mechanisms of inorganic reactions, bioinorganic chemistry, and relevant aspects of organometallic chemistry, solid-state phenomena, and chemical bonding theory. Emphasis is placed on the synthesis, structure, thermodynamics, reactivity, spectroscopy, and bonding properties of significant new and known compounds.
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