Shengfu Kang, Xiaohong Liu, Yi Zhang, Fang Fang, Wenjun Li, Pengfei Li
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引用次数: 0
Abstract
Organocatalytic dearomatization of β-naphthols has been achieved via an 1,6-conjugated addition of 2-naphthols to alkynyl 7-methylene-7H-indoles in situ generated from α-(7-indolyl)methanols. In the presence of racemic phosphoric acid, a series of tetrasubstituted allenes was obtained in high yields. Particularly, with the aid of chiral phosphoric acid, asymmetric dearomatization of β-naphthols was investigated, affording axially chiral tetrasubstituted allenes with moderate enantioselectivity.
期刊介绍：
Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry.
The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.
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