Albumin-Loaded Silica Nanomaterials Functionalized with Organotin(IV) Agents: Theranostic Materials Against Triple-Negative Breast Cancer (Adv. Therap. 10/2024)

IF 3.7 4区 医学 Q2 PHARMACOLOGY & PHARMACY Advanced Therapeutics Pub Date : 2024-10-13 DOI:10.1002/adtp.202470021
Victoria García-Almodóvar, Karina Ovejero-Paredes, Diana Díaz-García, José M. Méndez-Arriaga, Sanjiv Prashar, Marco Filice, Santiago Gómez-Ruiz
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Abstract

The cover image of article 2400114 by Marco Filice, Santiago Gómez-Ruiz, and co-workers illustrates the action and high potential of albumin-loaded silica-based porous nanomaterials functionalized with organotin(IV) cytotoxic agents. These systems adequately functionalized with both fluorescein derivatives and indocyanine green moieties can be applied as theranostic materials to target, track, internalize and decrease the viability of triple negative breast cancer cells.

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用有机锡(IV)制剂功能化的白蛋白负载二氧化硅纳米材料:针对三阴性乳腺癌的治疗材料(Adv.)
Marco Filice、Santiago Gómez-Ruiz 及其合作者撰写的文章 2400114 的封面图片说明了白蛋白负载硅基多孔纳米材料与有机锡(IV)细胞毒剂功能化的作用和巨大潜力。这些被荧光素衍生物和吲哚菁绿分子充分功能化的系统可用作治疗材料,靶向、追踪、内化并降低三阴性乳腺癌细胞的活力。
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来源期刊
Advanced Therapeutics
Advanced Therapeutics Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
7.10
自引率
2.20%
发文量
130
期刊最新文献
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