C. Fikri , L. Bendaoud , M. Aboudourib , O. Hocar , S. Amal
{"title":"Acute localized exanthematous pustulosis caused by topical plant","authors":"C. Fikri , L. Bendaoud , M. Aboudourib , O. Hocar , S. Amal","doi":"10.1016/j.reval.2024.104147","DOIUrl":null,"url":null,"abstract":"<div><div>A 42-year-old woman presented with an acute eruption of multiple non-follicular pustules on an erythematous base, localized on the leg and hip, with mild pruritus. No mucosal or nail involvement. It appeared a few hours after the application of the medicinal plant “<em>Copparis</em><em>s</em><em>pinosa</em>” for sciatica in the leg and disappeared after withdrawing the plant. The diagnosis of ALEP was made according to recently proposed diagnostic criteria for acute localized exanthematous pustulosis (ALEP). ALEP is a rare skin reaction described as multiple non-follicular and sterile pustules developing on an erythematous background. The pathogenesis of ALEP is largely unknown. It is drug-induced in 84%, mainly by antibiotics, and non-drug-induced in 16%, mainly by herbal medicines. Herein, we report the first case of PEAL in Morocco caused by a herbal medicine, <em>Copparis</em><em>s</em><em>pinosa</em>.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 2","pages":"Article 104147"},"PeriodicalIF":0.3000,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue Francaise d Allergologie","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1877032024003683","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A 42-year-old woman presented with an acute eruption of multiple non-follicular pustules on an erythematous base, localized on the leg and hip, with mild pruritus. No mucosal or nail involvement. It appeared a few hours after the application of the medicinal plant “Copparisspinosa” for sciatica in the leg and disappeared after withdrawing the plant. The diagnosis of ALEP was made according to recently proposed diagnostic criteria for acute localized exanthematous pustulosis (ALEP). ALEP is a rare skin reaction described as multiple non-follicular and sterile pustules developing on an erythematous background. The pathogenesis of ALEP is largely unknown. It is drug-induced in 84%, mainly by antibiotics, and non-drug-induced in 16%, mainly by herbal medicines. Herein, we report the first case of PEAL in Morocco caused by a herbal medicine, Copparisspinosa.
期刊介绍:
La Revue Française d''Allergologie : un véritable forum pour faire connaître des travaux originaux et permettre la diffusion de l''information auprès de toutes les spécialités concernées par les pathologies allergiques. La Revue Française d''Allergologie (8 numéros par an) est au carrefour de nombreuses spécialités - dermatologie, pédiatrie, ORL, pneumologie, ophtalmologie, médecine interne - qui, toutes, ont à traiter des maladies allergiques. Les symptômes des allergies fondés sur des mécanismes communs sont le plus souvent associés et se succèdent chez un même patient. En forte progression depuis 20 ans, les maladies allergiques sont dans l''attente de perfectionnements et d''avancées thérapeutiques qui permettront aux nombreux patients qui en sont atteints de mieux vivre avec leurs allergies. La Revue Française d''Allergologie se veut donc un véritable forum de discussions et d''échanges entre tous les spécialistes confrontés aux pathologies