V. G. Amelin, G. M. Beschastnova, Z. A. Ch. Shogah, A. V. Tretyakov, L. K. Kish
{"title":"Non-Destructive Analysis of Tetracycline Drugs by the Digital Colormetric Method Using a Smartphone and the Photometrix Pro® Software","authors":"V. G. Amelin, G. M. Beschastnova, Z. A. Ch. Shogah, A. V. Tretyakov, L. K. Kish","doi":"10.3103/S0027131424700354","DOIUrl":null,"url":null,"abstract":"<p>A nondestructive analysis of tetracyclines in drugs by their own fluorescence using a smartphone and a device printed on a 3D printer is proposed. The possibility of using chemometric methods, which reduce the analysis time and visualize the obtained data, is shown. The dataset is processed by principal component analysis (PCA), hierarchical cluster analysis (HCA), partial least squares (PLS) regression, and least squares using the PhotoMetrix PRO<sup>®</sup> software. The use of chemometric methods of analysis to determine the concentration of the active substance and identify the manufacturer of medicinal products is considered.</p>","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"79 5","pages":"325 - 333"},"PeriodicalIF":0.7000,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Moscow University Chemistry Bulletin","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.3103/S0027131424700354","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A nondestructive analysis of tetracyclines in drugs by their own fluorescence using a smartphone and a device printed on a 3D printer is proposed. The possibility of using chemometric methods, which reduce the analysis time and visualize the obtained data, is shown. The dataset is processed by principal component analysis (PCA), hierarchical cluster analysis (HCA), partial least squares (PLS) regression, and least squares using the PhotoMetrix PRO® software. The use of chemometric methods of analysis to determine the concentration of the active substance and identify the manufacturer of medicinal products is considered.
期刊介绍：
Moscow University Chemistry Bulletin is a journal that publishes review articles, original research articles, and short communications on various areas of basic and applied research in chemistry, including medical chemistry and pharmacology.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
