{"title":"Recent Advances in the Electrochemical Functionalization of Imidazoheterocycles","authors":"Sifeng Li","doi":"10.1002/adsc.202401064","DOIUrl":null,"url":null,"abstract":"Imidazoheterocycles have extensive applications in the pharmaceutical industry and agrochemicals. A comprehensive overview has been provided on the current advancements in electrochemical functionalization, which has been classified ten different types of reactions. Electrochemical synthesis has emerged as a highly effective method for producing organic molecules, especially in the context of sustainable development. Employing electrons as the traceless oxidant, several C–H functionalization reactions of imidazo-fused heterocycles have been achieved at either the C3 or C5 positions. Electrons may serve as the reducing agent to synthesize pyridine rings that are either partially or fully saturated in imidazo[1,2-a]pyridines. The purpose of the review is to attract the interest of the scientific community and promote additional research on the functionalization of imidazoheterocycles using electrochemical methods.","PeriodicalId":118,"journal":{"name":"Advanced Synthesis & Catalysis","volume":"7 1","pages":""},"PeriodicalIF":4.4000,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Synthesis & Catalysis","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/adsc.202401064","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Imidazoheterocycles have extensive applications in the pharmaceutical industry and agrochemicals. A comprehensive overview has been provided on the current advancements in electrochemical functionalization, which has been classified ten different types of reactions. Electrochemical synthesis has emerged as a highly effective method for producing organic molecules, especially in the context of sustainable development. Employing electrons as the traceless oxidant, several C–H functionalization reactions of imidazo-fused heterocycles have been achieved at either the C3 or C5 positions. Electrons may serve as the reducing agent to synthesize pyridine rings that are either partially or fully saturated in imidazo[1,2-a]pyridines. The purpose of the review is to attract the interest of the scientific community and promote additional research on the functionalization of imidazoheterocycles using electrochemical methods.
期刊介绍:
Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry.
The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.