Prevalence of Pertactin-Deficient Bordetella pertussis Isolates, Slovenia

IF 7.2 2区 医学 Q1 IMMUNOLOGY Emerging Infectious Diseases Pub Date : 2024-10-17 DOI:10.3201/eid3011.231393
Alex-Mikael Barkoff, Tamara Kastrin, Katja Seme, Marta Grgič Vitek, Jussi Mertsola, Qiushui He
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Abstract

In Slovenia, primary acellular pertussis vaccines (ACVs) containing pertactin (PRN) were mostly used during 1999–2016; ACVs without PRN were introduced in 2017. Among 123 Bordetella pertussis strains collected during 2002–2020, a total of 48 were PRN-deficient; 44 were collected after 2017. Changes to ACVs could increase PRN-deficient B. pertussis and infections.

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斯洛文尼亚百日咳博德特氏菌菌株中缺乏伯特金的流行情况
在斯洛文尼亚,1999-2016 年间大多使用含有百日咳素 (PRN) 的初级无细胞百日咳疫苗 (ACV);2017 年开始使用不含 PRN 的 ACV。在 2002-2020 年间收集的 123 株百日咳杆菌中,共有 48 株缺乏百日咳素;其中 44 株是在 2017 年之后收集的。ACV 的变化可能会增加 PRN 缺乏的百日咳杆菌和感染。
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来源期刊
Emerging Infectious Diseases
Emerging Infectious Diseases 医学-传染病学
CiteScore
17.30
自引率
1.70%
发文量
505
审稿时长
1 months
期刊介绍: Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination. Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.
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