A Mathematical Analysis of the Impact of Immature Mosquitoes on the Transmission Dynamics of Malaria

IF 0.9 Q3 MATHEMATICS, APPLIED Computational and Mathematical Methods Pub Date : 2024-10-18 DOI:10.1155/2024/5589805
Nantogmah Abdulai Sualey, Philip N. A. Akuka, Baba Seidu, Joshua Kiddy K. Asamoah
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Abstract

This study delves into the often-overlooked impact of immature mosquitoes on the dynamics of malaria transmission. By employing a mathematical model, we explore how these aquatic stages of the vector shape the spread of the disease. Our analytical findings are corroborated through numerical simulations conducted using the Runge–Kutta fourth-order method in MATLAB. Our research highlights a critical factor in malaria epidemiology: the basic reproduction number . We demonstrate that when is below unity , the disease-free equilibrium exhibits local asymptotic stability. Conversely, when surpasses unity , the disease-free equilibrium becomes unstable, potentially resulting in sustained malaria transmission. Furthermore, our analysis covers equilibrium points, stability assessments, bifurcation phenomena, and sensitivity analyses. These insights shed light on essential aspects of malaria control strategies, offering valuable guidance for effective intervention measures.

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未成熟蚊子对疟疾传播动态影响的数学分析
这项研究深入探讨了通常被忽视的未成熟蚊子对疟疾传播动态的影响。通过使用数学模型,我们探讨了病媒的这些水生阶段如何影响疾病的传播。我们的分析结果通过在 MATLAB 中使用 Runge-Kutta 四阶方法进行的数值模拟得到了证实。我们的研究强调了疟疾流行病学中的一个关键因素:基本繁殖数。我们证明,当基本繁殖数小于 1 时,无病均衡表现出局部渐进稳定性。相反,当超过 1 时,无病平衡变得不稳定,可能导致疟疾持续传播。此外,我们的分析还包括平衡点、稳定性评估、分岔现象和敏感性分析。这些见解揭示了疟疾控制策略的重要方面,为采取有效的干预措施提供了宝贵的指导。
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