Research progress on machine algorithm prediction of liver cancer prognosis after intervention therapy.

IF 3.6 3区 医学 Q2 ONCOLOGY American journal of cancer research Pub Date : 2024-09-25 eCollection Date: 2024-01-01 DOI:10.62347/BEAO1926
Feng Guo, Hao Hu, Hao Peng, Jia Liu, Chengbo Tang, Hao Zhang
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Abstract

The treatment for liver cancer has transitioned from traditional surgical resection to interventional therapies, which have become increasingly popular among patients due to their minimally invasive nature and significant local efficacy. However, with advancements in treatment technologies, accurately assessing patient response and predicting long-term survival has become a crucial research topic. Over the past decade, machine algorithms have made remarkable progress in the medical field, particularly in hepatology and prognosis studies of hepatocellular carcinoma (HCC). Machine algorithms, including deep learning and machine learning, can identify prognostic patterns and trends by analyzing vast amounts of clinical data. Despite significant advancements, several issues remain unresolved in the prognosis prediction of liver cancer using machine algorithms. Key challenges and main controversies include effectively integrating multi-source clinical data to improve prediction accuracy, addressing data privacy and ethical concerns, and enhancing the transparency and interpretability of machine algorithm decision-making processes. This paper aims to systematically review and analyze the current applications and potential of machine algorithms in predicting the prognosis of patients undergoing interventional therapy for liver cancer, providing theoretical and empirical support for future research and clinical practice.

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干预治疗后肝癌预后的机器算法预测研究进展。
肝癌的治疗方法已从传统的手术切除过渡到介入疗法,介入疗法因其微创性和显著的局部疗效而越来越受到患者的青睐。然而,随着治疗技术的进步,准确评估患者反应和预测长期生存率已成为一个重要的研究课题。过去十年来,机器算法在医学领域取得了显著进展,尤其是在肝病学和肝细胞癌(HCC)预后研究方面。包括深度学习和机器学习在内的机器算法可以通过分析大量临床数据来识别预后模式和趋势。尽管取得了重大进展,但在使用机器算法预测肝癌预后方面仍有几个问题尚未解决。关键挑战和主要争议包括有效整合多源临床数据以提高预测准确性、解决数据隐私和伦理问题,以及提高机器算法决策过程的透明度和可解释性。本文旨在系统回顾和分析当前机器算法在预测肝癌介入治疗患者预后方面的应用和潜力,为未来研究和临床实践提供理论和实证支持。
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263
期刊介绍: The American Journal of Cancer Research (AJCR) (ISSN 2156-6976), is an independent open access, online only journal to facilitate rapid dissemination of novel discoveries in basic science and treatment of cancer. It was founded by a group of scientists for cancer research and clinical academic oncologists from around the world, who are devoted to the promotion and advancement of our understanding of the cancer and its treatment. The scope of AJCR is intended to encompass that of multi-disciplinary researchers from any scientific discipline where the primary focus of the research is to increase and integrate knowledge about etiology and molecular mechanisms of carcinogenesis with the ultimate aim of advancing the cure and prevention of this increasingly devastating disease. To achieve these aims AJCR will publish review articles, original articles and new techniques in cancer research and therapy. It will also publish hypothesis, case reports and letter to the editor. Unlike most other open access online journals, AJCR will keep most of the traditional features of paper print that we are all familiar with, such as continuous volume, issue numbers, as well as continuous page numbers to retain our comfortable familiarity towards an academic journal.
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