Nanobots: An endodontist saviour.

IF 1.9 Bioinformation Pub Date : 2024-08-31 eCollection Date: 2024-01-01 DOI:10.6026/973206300200898
Saurav Bathla, Manoj Kumar Hans, Saurav Kumar Dutta, Shyamalima Bhattacharyya, Anindita Talukdar, Sana Saifi
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Abstract

The application of nanoparticles in the form of solution for irrigation, medication and as an additive for sealer/restorative material has been evaluated to improve the antibacterial efficacy in the field of endodontics. Recently developed nanobots are injected into the teeth to destroy pathogens and they are more effective in root canal therapy. They are helical shaped and composed of silicon dioxide with iron embedded into the silica body to provide magnetic properties. They are also able to move within the dentinal tubules and are manipulated peripherally through a low-intensity magnetic field. These nanobots can be administered into the cleaned central canal of a tooth samples which are immersed in deionized water and their motions are monitored using a near-infrared imaging technique to produce heat which is a hyperthermia-based bactericidal method which help to eradicate the surrounding pathogens.

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纳米机器人:牙髓病学家的救星
纳米粒子以溶液的形式应用于冲洗、药物治疗以及作为封闭剂/修复材料的添加剂,已被评估用于提高根管治疗领域的抗菌效果。最近开发的纳米机器人被注入牙齿以消灭病原体,在根管治疗中更为有效。它们呈螺旋状,由二氧化硅组成,硅体中嵌入铁元素,具有磁性。它们还能在牙本质小管内移动,并通过低强度磁场进行外围操控。可以将这些纳米机器人放入清洁过的牙齿中央管中,然后将其浸入去离子水中,利用近红外成像技术监测它们的运动,从而产生热量,这是一种基于热疗的杀菌方法,有助于消灭周围的病原体。
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来源期刊
Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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