Aberration compensation in Doppler holography of the human eye fundus by subaperture signal correlation.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS Biomedical optics express Pub Date : 2024-09-04 eCollection Date: 2024-10-01 DOI:10.1364/BOE.528568
Zofia Bratasz, Olivier Martinache, Julia Sverdlin, Damien Gatinel, Michael Atlan
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Abstract

The process of obtaining images of capillary vessels in the human eye's fundus using Doppler holography encounters difficulties due to ocular aberrations. To enhance the accuracy of these images, it is advantageous to apply an adaptive aberration correction technique. This study focuses on numerical Shack-Hartmann, which employs sub-pupil correlation as the wavefront sensing method. Application of this technique to Doppler holography encounters unique challenges due to the holographic detection properties. A detailed comparative analysis of the regularization technique against direct gradient integration in the estimation of aberrations is made. Two different reference images for the measurement of image shifts across subapertures are considered. The comparison reveals that direct gradient integration exhibits greater effectiveness in correcting asymmetrical aberrations.

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通过子光圈信号相关性对人眼眼底多普勒全息成像中的像差进行补偿。
在使用多普勒全息技术获取人眼眼底毛细血管图像的过程中,会遇到眼球像差带来的困难。为了提高这些图像的精确度,应用自适应像差校正技术是非常有利的。本研究的重点是数值 Shack-Hartmann,它采用瞳孔下相关性作为波前感应方法。由于全息检测的特性,将这种技术应用于多普勒全息技术会遇到独特的挑战。在估计像差时,对正则化技术与直接梯度积分进行了详细的比较分析。考虑了两种不同的参考图像,用于测量跨子孔径的图像偏移。比较结果表明,直接梯度积分在校正不对称像差方面表现出更大的有效性。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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