An early economic analysis of medical cannabis for the treatment of chronic pain.

IF 1.8 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Expert Review of Pharmacoeconomics & Outcomes Research Pub Date : 2024-10-16 DOI:10.1080/14737167.2024.2412248
Shanna Marrinan, Anne K Schlag, Michael Lynskey, Callie Seaman, Mike P Barnes, Mike Morgan-Giles, David Nutt
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Abstract

Background: Cannabis-based medicinal products (CBMPs) are increasingly demonstrating effectiveness in treating a wide range of conditions, with a relatively high safety profile in clinical usage compared to other prescription pain medications and few contraindications. Consultation and other prescription-related costs are, at present, higher for CBMPs than for some other treatment options, leading to some concern around wider prescribing.

Research design and methods: An early cost-effectiveness model was developed to estimate the impact of prescribing CBMPs alone and/or in addition to analgesics, physiotherapy, and cognitive behavioral therapy for chronic pain in the UK for 1 year.

Results: Due to their comparative effectiveness, CBMPs were found to be cost saving. Various scenarios were model tested; in all scenarios where CBMPs decrease pain-level states, less resource use is required. Increased efficacy of 5% was conservatively assumed based on current Real-World Evidence. In this scenario, CBMPs were significantly more cost-effective, and as costs relating to the prescribing of these continue to fall, relative savings are predicted to increase.

Conclusion: These findings highlight the substantial cost saving that CBMPs may represent for the treatment of chronic pain patients, and the benefits for healthcare providers as a treatment for this often hard-to-treat population.

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对医用大麻治疗慢性疼痛的早期经济分析。
背景:以大麻为基础的医药产品(CBMPs)越来越多地显示出对多种疾病的治疗效果,与其他处方止痛药相比,其临床使用的安全性相对较高,禁忌症也很少。目前,CBMP 的咨询和其他与处方相关的费用要高于其他一些治疗方案,这引起了人们对更广泛处方的关注:研究设计和方法:我们开发了一个早期成本效益模型,以估算在英国单独处方 CBMPs 和/或在镇痛剂、理疗和认知行为疗法之外处方 CBMPs 对慢性疼痛 1 年的影响:结果:由于CBMP的比较有效性,CBMP被认为可以节约成本。对各种情况进行了模型试验;在 CBMPs 降低疼痛程度状态的所有情况下,所需的资源使用量都减少了。根据目前的真实世界证据,保守假设疗效提高了 5%。在这种情况下,CBMPs 的成本效益明显更高,随着开具 CBMPs 相关处方的成本不断下降,预计相对节省的费用也会增加:这些研究结果凸显了 CBMPs 在治疗慢性疼痛患者方面可节省的大量成本,以及医疗服务提供者在治疗这类通常难以治疗的人群方面可获得的益处。
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来源期刊
Expert Review of Pharmacoeconomics & Outcomes Research
Expert Review of Pharmacoeconomics & Outcomes Research HEALTH CARE SCIENCES & SERVICES-PHARMACOLOGY & PHARMACY
CiteScore
4.00
自引率
4.30%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Expert Review of Pharmacoeconomics & Outcomes Research (ISSN 1473-7167) provides expert reviews on cost-benefit and pharmacoeconomic issues relating to the clinical use of drugs and therapeutic approaches. Coverage includes pharmacoeconomics and quality-of-life research, therapeutic outcomes, evidence-based medicine and cost-benefit research. All articles are subject to rigorous peer-review. The journal adopts the unique Expert Review article format, offering a complete overview of current thinking in a key technology area, research or clinical practice, augmented by the following sections: Expert Opinion – a personal view of the data presented in the article, a discussion on the developments that are likely to be important in the future, and the avenues of research likely to become exciting as further studies yield more detailed results Article Highlights – an executive summary of the author’s most critical points.
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