{"title":"Recent Advances in the Synthesis and Optical Applications of Acridine-based Hybrid Fluorescent Dyes.","authors":"Mehdi Pordel, Hanieh Gheibi, Ayda Sharif","doi":"10.1007/s10895-024-04001-3","DOIUrl":null,"url":null,"abstract":"<p><p>Acridine-based hybrid fluorescent dyes represent a category of dyes that integrate the acridine chromophore with other functional groups or materials to enhance their fluorescence properties. These dyes have garnered substantial attention across various domains, encompassing bioimaging, sensing, and optoelectronics. In recent years, researchers have directed their efforts toward fabricating acridine-based hybrid fluorescent dyes with improved water solubility, biocompatibility, and targeting capabilities. These advancements have facilitated their utilization in biological imaging applications, such as monitoring cellular processes, investigating protein-protein interactions, and detecting specific biomolecules. This review delineates the recent progress in synthesizing acridine-based hybrid fluorescent dyes and their applications in optical properties over the past decade. This review is anticipated to catalyze the development of innovative fluorescent materials featuring heightened properties and functionalities.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fluorescence","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10895-024-04001-3","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
Acridine-based hybrid fluorescent dyes represent a category of dyes that integrate the acridine chromophore with other functional groups or materials to enhance their fluorescence properties. These dyes have garnered substantial attention across various domains, encompassing bioimaging, sensing, and optoelectronics. In recent years, researchers have directed their efforts toward fabricating acridine-based hybrid fluorescent dyes with improved water solubility, biocompatibility, and targeting capabilities. These advancements have facilitated their utilization in biological imaging applications, such as monitoring cellular processes, investigating protein-protein interactions, and detecting specific biomolecules. This review delineates the recent progress in synthesizing acridine-based hybrid fluorescent dyes and their applications in optical properties over the past decade. This review is anticipated to catalyze the development of innovative fluorescent materials featuring heightened properties and functionalities.
期刊介绍:
Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.