Recent Advances in the Synthesis and Optical Applications of Acridine-based Hybrid Fluorescent Dyes.

IF 2.6 4区 化学 Q2 BIOCHEMICAL RESEARCH METHODS Journal of Fluorescence Pub Date : 2024-10-17 DOI:10.1007/s10895-024-04001-3
Mehdi Pordel, Hanieh Gheibi, Ayda Sharif
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Abstract

Acridine-based hybrid fluorescent dyes represent a category of dyes that integrate the acridine chromophore with other functional groups or materials to enhance their fluorescence properties. These dyes have garnered substantial attention across various domains, encompassing bioimaging, sensing, and optoelectronics. In recent years, researchers have directed their efforts toward fabricating acridine-based hybrid fluorescent dyes with improved water solubility, biocompatibility, and targeting capabilities. These advancements have facilitated their utilization in biological imaging applications, such as monitoring cellular processes, investigating protein-protein interactions, and detecting specific biomolecules. This review delineates the recent progress in synthesizing acridine-based hybrid fluorescent dyes and their applications in optical properties over the past decade. This review is anticipated to catalyze the development of innovative fluorescent materials featuring heightened properties and functionalities.

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基于吖啶的混合荧光染料的合成和光学应用的最新进展。
吖啶基杂化荧光染料是一类将吖啶发色团与其他官能团或材料整合在一起以增强其荧光特性的染料。这些染料在生物成像、传感和光电子学等各个领域都引起了广泛关注。近年来,研究人员致力于制造具有更好的水溶性、生物相容性和靶向能力的吖啶基杂化荧光染料。这些进步促进了它们在生物成像应用中的应用,如监测细胞过程、研究蛋白质与蛋白质之间的相互作用以及检测特定的生物分子。本综述介绍了过去十年来在合成吖啶基杂化荧光染料及其在光学特性方面应用的最新进展。预计这篇综述将促进具有更高特性和功能的创新型荧光材料的开发。
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来源期刊
Journal of Fluorescence
Journal of Fluorescence 化学-分析化学
CiteScore
4.60
自引率
7.40%
发文量
203
审稿时长
5.4 months
期刊介绍: Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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