Association between adverse childhood experiences and pregnancy morbidities: A nationwide online-based cross-sectional study.

IF 1.6 4区医学 Q3 OBSTETRICS & GYNECOLOGY Journal of Obstetrics and Gynaecology Research Pub Date : 2024-10-16 DOI:10.1111/jog.16124

Yuto Maeda, Takahiro Tabuchi, Takeo Fujiwara

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Abstract

Objective: To examine the association between adverse childhood experiences (ACEs) and pregnancy morbidities, including preterm birth (PTB), gestational diabetes (GDM), preeclampsia, and small-for-gestational-age (SGA) among the general population in Japan.

Methods: The data were from the JACSIS study, an online-based nationwide survey conducted from July to August 2021 in Japan (N = 5444). ACEs included physical, sexual, and psychological abuse, neglect, childhood poverty, bully victimization, domestic violence, parental death, and parental divorce. Pregnancy morbidities, including PTB, GDM, preeclampsia, and SGA were identified through questionnaires. A multivariable logistic regression model was applied.

Results: Of 5444 women, 2778 (51.0%) had no ACEs, and 374 (6.9%) had four or more ACEs. A dose-response association was found between total ACE score and PTB and preeclampsia (p-value: 0.016 and 0.001). Women with four or more ACE scores showed higher risks of preeclampsia (adjusted odds ratio [aOR] [95% confidence interval, CI]: 3.06 [1.57-5.94], p-value: 0.001). Besides, those with two or three ACEs had higher risks of PTB (aOR [95%CI]: 1.42 [1.01-2.02], p-value: 0.046, and aOR [95%CI]: 1.61 [1.04-2.50], p-value: 0.041), and women with one ACE showed a higher risk of GDM (aOR [95%CI]: 1.34 [1.02-1.77], p-value: 0.035). SGA was not associated with ACEs.

Conclusion: ACEs were associated with an increased risk of PTB, preeclampsia, and GDM, but not SGA among the general population in Japan.

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童年不良经历与妊娠期疾病之间的关系：一项基于网络的全国性横断面研究。

目的研究日本普通人群中童年不良经历（ACE）与妊娠期疾病（包括早产（PTB）、妊娠期糖尿病（GDM）、子痫前期和小于胎龄（SGA））之间的关系：这些数据来自于JACSIS研究，该研究是2021年7月至8月在日本进行的一项基于网络的全国性调查（N = 5444）。ACE包括身体虐待、性虐待和心理虐待、忽视、童年贫困、恶霸伤害、家庭暴力、父母死亡和父母离异。通过问卷调查确定了妊娠期疾病，包括先兆流产、糖尿病、子痫前期和 SGA。采用多变量逻辑回归模型进行分析：在 5444 名妇女中，2778 人（51.0%）没有 ACE，374 人（6.9%）有四项或四项以上 ACE。发现 ACE 总分与 PTB 和子痫前期之间存在剂量反应关系（P 值：0.016 和 0.001）。有四项或四项以上 ACE 评分的妇女患先兆子痫的风险更高（调整后的几率比 [aOR] [95% 置信区间，CI]：3.06 [1.57-5.001] ）：3.06 [1.57-5.94]，P 值：0.001）。此外，有两个或三个 ACE 的孕妇患先兆流产的风险更高（aOR [95%CI]：1.42[1.01-2.02]，P 值：0.046，和 aOR [95%CI]：1.61[1.04-2.50]，p 值：0.041），而患有一种 ACE 的妇女发生 GDM 的风险更高（aOR [95%CI]：1.34 [1.02-1.77]，p 值：0.035）。SGA与ACE无关：在日本的普通人群中，ACE 与 PTB、子痫前期和 GDM 的风险增加有关，但与 SGA 无关。

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来源期刊

Journal of Obstetrics and Gynaecology Research 医学-妇产科学

CiteScore

3.10

自引率

0.00%

发文量

376

审稿时长

3-6 weeks

期刊介绍： The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynecology and of the Japan Society of Obstetrics and Gynecology, and aims to provide a medium for the publication of articles in the fields of obstetrics and gynecology. The Journal publishes original research articles, case reports, review articles and letters to the editor. The Journal will give publication priority to original research articles over case reports. Accepted papers become the exclusive licence of the Journal. Manuscripts are peer reviewed by at least two referees and/or Associate Editors expert in the field of the submitted paper.