Journal of Obstetrics and Gynaecology Research最新文献

{"title":"Comparison of clinical effects between sacrospinous ligament fixation and extraperitoneal high uterosacral ligament suspension for patients: A retrospective cohort clinical trials","authors":"Jiaoyang Song,&nbsp;Xiaohui Sun,&nbsp;Bing Xie,&nbsp;Shiyan Wang,&nbsp;Lei Gao,&nbsp;Xiuli Sun","doi":"10.1111/jog.16264","DOIUrl":"https://doi.org/10.1111/jog.16264","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of the study is to compare the effect of extraperitoneal high uterosacral ligament suspension (EHUS) and sacrospinous ligament fixation on lower urinary tract symptoms (LUTS) and anatomical reduction in patients with pelvic organ prolapse (POP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective cohort study concluded 91 patients with POP who underwent EHUS or sacrospinous ligament fixation (SSLF) for apical repair. The primary outcome was the effect of the two operations on anatomical reduction. The main secondary outcomes included improvement of questionnaire scores, satisfaction, and subjective prolapse rate. Categorical variables, Student's <i>t</i> test, and the Mann–Whitney <i>U</i> test were used for analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All patients' scores of POP-Q were significantly improved after surgery. The scores of urinary frequency and urgency in the SSLF group improved significantly from 6 months after surgery, with statistical significance (<i>p</i> &lt; 0.05), while the scores of nocturia and urgency in the EHUS group improved from 1 month after surgery (<i>p</i> &lt; 0.05). The scores of questionnaires in both groups were significantly lower than those before surgery, while the EHUS group showed more significant improvement (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>EHUS is easy to operate, has a short operative time, fewer perioperative and postoperative complications, and the apical can be suspended well if the prolapse is not severe. It also has a certain degree of relief for LUTS, which is a new type of operation that is worthy of clinical promotion.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-indicated and physical examination-indicated cervical cerclage in twin versus singleton gestations","authors":"Daphna Amitai Komem,&nbsp;Raanan Meyer,&nbsp;Itai Yagel,&nbsp;Daniel Shai,&nbsp;Roy Mashiach,&nbsp;Israel Hendler,&nbsp;Shali Mazaki-Tovi,&nbsp;Yoav Yinon","doi":"10.1111/jog.16263","DOIUrl":"https://doi.org/10.1111/jog.16263","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To compare the safety and efficacy of ultrasound- and physical examination-indicated cervical cerclage in twin versus singleton gestations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective cohort study of all ultrasound-indicated (cervical length ≤ 25 mm) and physical examination-indicated cerclage cases performed over a 9-year period. The primary outcome was the time interval from cerclage placement to delivery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study cohort included 94 singleton and 16 twin pregnancies. The time interval from cerclage placement to delivery was comparable in singleton and twin gestations (14.77 vs. 12.07 weeks, <i>p</i> = 0.11), as were the rates of preterm births before 28 and 32 weeks. The rate of alive newborns &gt;24 weeks was lower in the twin group (71.9% vs. 88.3%, <i>p</i> = 0.028). Regression analysis identified that cervical dilation, but not twin gestation, was the only factor independently associated with an increased risk for birth before 32 weeks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Ultrasound-indicated and physical examination-indicated cerclage had comparable efficacy in prolonging pregnancy in twin and singleton gestations, though live birth rates were lower in twins.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jog.16263","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between the pelvic organ prolapse quantification system and vaginal noise: A cross-sectional study","authors":"Sima Shamshiri Khamene,&nbsp;Izat Mohammad Khawajah,&nbsp;Elham Feizabad,&nbsp;Maryam Sadr Ameli,&nbsp;Elahe Radmehr,&nbsp;Khadijeh Adabi","doi":"10.1111/jog.16257","DOIUrl":"https://doi.org/10.1111/jog.16257","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Vaginal noise (VN) has recently received attention as an important factor in women's sexual life and satisfaction. It can be influenced by various factors such as genetics, childbirth, age, menopause, and many other factors that are yet to be discovered. The purpose of this study is to investigate the relationship between the Pelvic Organ Prolapse Quantification (POP-Q) system and vaginal sounds and to find out the correlation between VN and sexual function.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The correlation between POP-Q measurements and VN and its impact on female sexual life was investigated in 851 women referred to the female pelvic medicine and reconstructive surgery clinic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>VN was reported in 26.3% of the patients. It was significantly higher in younger cases and premenopause. VN had no significant association with cigarettes, BMI, gravidity, or abortion. Feeling of heaviness in the pelvic area, dyspareunia, anorgasmia, and partners sexual dissatisfaction were significantly higher in cases with VN. No significant relationship was found between VN and reduction in sexual desire and vaginal dryness. Patients with higher-stage anterior vaginal wall prolapse had significantly fewer complaints of VN. Stage 3 anterior vaginal wall prolapse had a lower chance of vaginal noise, OR = 0.2. Mean Aa and Ba were significantly higher in cases without VN.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In this study, we found a significant relationship between VN and anterior vaginal wall prolapse in a way that Stage 3 had a lesser chance of VN. No relation was found in the posterior or apical vaginal prolapse.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to “Will the day come when opinion and letter pieces disappear from the medical journals?”","authors":"Himel Mondal","doi":"10.1111/jog.16262","DOIUrl":"https://doi.org/10.1111/jog.16262","url":null,"abstract":"","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proposals for improving maternal safety (2023 edition): Insights from the analysis of maternal deaths in Japan","authors":"Japan Maternal Death Exploratory Committee","doi":"10.1111/jog.16244","DOIUrl":"https://doi.org/10.1111/jog.16244","url":null,"abstract":"<p>The maternal mortality rate remains approximately 4 per 100 000 deliveries. Between January 2010 and July 2024, 629 maternal deaths were reported, of which 590 were reviewed. The Maternal Safety Proposal summarizes these cases. Deaths from obstetric hemorrhage decreased from 28% in 2010 to 7% in 2019 but rose to approximately 20% in 2022 and dropped to 10% in 2023. In the past 4 years, suicide has surpassed obstetric hemorrhage as a leading cause of death. In 2023, intracranial hemorrhage/infarction became the leading cause, with six cases reported. Cardiopulmonary collapse from amniotic fluid embolism, along with cardiovascular, infectious, and pulmonary diseases, has remained stable at 6%–10%. Initial symptoms leading to death occurred during the antepartum (38%), intrapartum (41%), or postpartum periods (21%), with cases distributed across general hospitals, small maternity delivery facilities, and non-medical settings, including homes. The following are the year's maternal safety proposals:\u0000 </p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jog.16244","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exosomal-complement system activation in preeclampsia","authors":"M. David,&nbsp;N. Maharaj,&nbsp;A. Krishnan","doi":"10.1111/jog.16255","DOIUrl":"https://doi.org/10.1111/jog.16255","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Preeclampsia (PE) is a severe pregnancy-related disorder characterized by hypertension and multi-organ failure, primarily affecting the maternal vasculature and placenta. The aim of this review is to explain the molecular mechanisms behind PE by investigating the relationship between exosome release and complement activation, which could provide insight into potential therapeutic targets.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This review analyzes existing literature on the role of the complement system and exosomes in the pathophysiology of PE. The focus is on how abnormal complement activation contributes to inflammation and vascular dysfunction, particularly in the placenta, and the role of trophoblast-derived exosomes carrying pathogenic molecules such as soluble fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sEng).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Findings from recent studies indicate that during PE, abnormal complement activation leads to severe inflammation and vascular dysfunction in the placenta. Additionally, exosomes, particularly those derived from trophoblasts, are present in higher concentrations in maternal circulation during PE and carry molecules that disrupt endothelial function. These factors contribute to the development of hypertension and other maternal complications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Understanding the interaction between complement activation and exosome release in PE may open avenues for novel therapeutic approaches. Targeting complement regulation and exosome-mediated signaling could potentially improve maternal and fetal outcomes, offering new strategies for managing this complex condition.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jog.16255","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated analysis of DNA methylation and transcriptome profiles to identify oxidative stress-related placenta-specific molecules for preeclampsia","authors":"Yang Xu,&nbsp;Xiaolin Zeng,&nbsp;Shuang Guo,&nbsp;Yuan Liao,&nbsp;Danqing Zhao","doi":"10.1111/jog.16209","DOIUrl":"https://doi.org/10.1111/jog.16209","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Preeclampsia (PE) is a pregnancy-specific hypertensive disorder and one of the leading causes of maternal mortality. However, its etiology and pathogenesis are not yet fully clarified. This study aimed to uncover methylation-regulated oxidative stress-related placenta-specific molecules in PE.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Two PE datasets, GSE57767 and GSE25906, were subjected into this study. The oxidative stress-related genes were derived from GeneCards database. Differential methylation and expression analysis were applied to identify methylation-regulated oxidative stress-related genes in PE. The methylation-regulated oxidative stress-related placenta-specific molecules were determined by receiver operating characteristic (ROC) analysis. The single-gene gene set enrichment analysis (GSEA) were executed using the R “clusterProfiler.” The transcription factor (TF)-gene regulatory network of placenta-specific molecules was created through Network Analyst database and Cytoscape software. The drug-gene network of placenta-specific molecules were developed through DGIdb database and Cytoscape software. Eventually, we further examined biomarker expression trends in the collected clinical samples using real time quantitative PCR (RT-qPCR).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A total of 13 methylation-regulated oxidative stress-related genes in PE were identified. Then, five genes (&lt;i&gt;VIM&lt;/i&gt;, &lt;i&gt;SNCA&lt;/i&gt;, &lt;i&gt;PIK3CG&lt;/i&gt;, &lt;i&gt;DNM2&lt;/i&gt;, and &lt;i&gt;BMP6&lt;/i&gt;) were authenticated as methylation-regulated oxidative stress-related placenta-specific molecules in PE by ROC curves, suggesting a potential clinical diagnostic value. Single-gene GSEA pointed to the linkage of these five genes to the immune-related pathways, ferroptosis, and oxidative phosphorylation. Finally, a TF-gene regulatory network containing 32 nodes and 38 edges and a drug-gene network containing 126 nodes and 123 edges were generated based on methylation-regulated oxidative stress-related placenta-specific molecules in PE. Ultimately, the experimental results confirmed that the expression trends of &lt;i&gt;VIM&lt;/i&gt;, &lt;i&gt;PIK3CG&lt;/i&gt;, and &lt;i&gt;BMP6&lt;/i&gt; in our collected clinical samples were in line with the expression trends in the GSE25906 dataset.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Three genes, &lt;i&gt;VIM&lt;/i&gt;, &lt;i&gt;PIK3CG&lt;/i&gt;, and &lt;i&gt;BMP6&lt;/i&gt;, were identified as methylation-regulated oxidative stress-related placenta-specific molecules in PE. This might have helped to understand the pathogenesis of the disease and might also have pro","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jog.16209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Underrecognized diagnostic discordance and delay in endometrial dedifferentiated and undifferentiated carcinoma","authors":"Saria Kawano,&nbsp;Hiroshi Yoshida,&nbsp;Nao Kikkawa,&nbsp;Mayumi Kobayashi-Kato,&nbsp;Yasuhito Tanase,&nbsp;Masaya Uno,&nbsp;Mitsuya Ishikawa","doi":"10.1111/jog.16260","DOIUrl":"https://doi.org/10.1111/jog.16260","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Dedifferentiated and undifferentiated endometrial carcinoma (DC/UC) is a rare subtype of endometrial cancer characterized by undifferentiated carcinoma components. This study aimed to investigate diagnostic discrepancies and delays in DC/UC and compare them with low-grade endometrioid carcinoma (LGEC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively analyzed 20 DC/UC and 40 LGEC cases finally diagnosed at our hospital (2016–2024). We compared the data of the two groups, including clinicopathologic characteristics and diagnostic intervals defined as the time from the date of initial biopsy to the date of definitive diagnosis. We assessed diagnostic discordances between preoperative diagnoses, including radiological, clinical, and biopsy, and final diagnoses with immunohistochemical analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>DC/UC cases exhibited significantly longer diagnostic intervals (median 46 vs. 5 days, <i>p</i> = 0.037) and required more biopsy attempts (median two vs. 1, <i>p</i> = 0.002) and immunohistochemical tests (median 19 vs. 6, <i>p</i> = 0.001) than LGEC cases. In preoperative diagnoses, 60% of DC/UC cases showed diagnostic discrepancies. Radiological findings frequently suggested uterine sarcoma in DC/UC (30%, 6/20). Only 50% of DC/UC were suggested via initial biopsy. Immunohistochemistry revealed mismatch repair deficiency in 70% of DC/UC cases.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Frequent diagnostic discrepancies and delays were observed in DC/UC, possibly due to its atypical imaging and histopathological features. Raising awareness of DC/UC's clinical and pathological characteristics is crucial to minimizing diagnostic delays. Given its frequency (at least 1% of endometrial cancers) and eligibility for emerging therapies, prioritizing DC/UC in differential diagnoses and improving diagnostic workflows through interdisciplinary collaboration are required for timely and effective treatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of attitudes toward sexuality and sexual function on marital satisfaction during pregnancy","authors":"Derya Öztürk Özen,&nbsp;Neslihan Yılmaz Sezer,&nbsp;Menekşe Nazlı Aker,&nbsp;Melike Demir Çaltekin","doi":"10.1111/jog.16258","DOIUrl":"https://doi.org/10.1111/jog.16258","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Aim of the study investigating the impact of attitudes toward sexuality and sexual function on marital satisfaction during pregnancy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study, in which a descriptive design was used, was conducted with 520 pregnant women. The Introductory Information Form, The Attitude Scale toward Sexuality During Pregnancy (AStSdP) (subdimensions: anxiety about sexual intercourse during pregnancy [anxiety], dysfunctional beliefs and values about sexuality during pregnancy [beliefs and values], and approving sexuality during pregnancy [approval]), Female Sexual Function Index (FSFI) (subdimensions: sexual function, including desire, arousal, lubrication, orgasm, satisfaction, and pain), and Marital Adjustment Scale (MAS) (subdimensions: family, sex, and self) were used for data collection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean AStSdP score was 104.61 ± 18.75, the mean FSFI score was 19.54 ± 8.91, and the mean MAS score was 48.58 ± 8.54. Negative attitudes toward sexuality during pregnancy were reported by 30% of the participants, while 79.4% experienced sexual dysfunction. The AStSdP, FSFI, and MAS scores exhibited a positive correlation. Additionally, adverse economic conditions, gestational week, Anxiety, Beliefs and Values, AStSdP scores, and arousal scores were significant predictors of marital satisfaction in pregnant women.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>There exists a positive relationship between attitudes toward sexuality during pregnancy, sexual function scores, and marital satisfaction. Moreover, attitudes toward sexuality during pregnancy influence marital satisfaction. Nurses and other antenatal team members should implement interventions to foster positive attitudes toward sexuality in pregnancy, as these can enhance marital satisfaction.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143554751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal arrhythmias: Current evidence of prenatal diagnosis and management","authors":"Takekazu Miyoshi","doi":"10.1111/jog.16256","DOIUrl":"https://doi.org/10.1111/jog.16256","url":null,"abstract":"<p>Fetal arrhythmias present as an irregular cardiac rhythm and heart rate. Fetal echocardiography and cardiotocography play a pivotal role in diagnosing and managing fetal arrhythmia. Fetal magnetocardiography and electrocardiography can provide electrical assessment but have several limitations; thus, prenatal diagnosis of fetal arrhythmia remains challenging. Most cases of fetal arrhythmia have a structurally normal heart with isolated premature contractions that spontaneously resolve in utero or after birth without treatment. Despite the theoretical advantage of fetoplacental circulation, progression to heart failure or hydrops is found in fetuses with tachy- or bradyarrhythmia due to the limited heart rate reserve. There is a clear clinical consensus on the efficacy of transplacental antiarrhythmic therapy using digoxin, sotalol, and flecainide for fetal supraventricular tachyarrhythmia. A recent Japanese multicenter clinical trial confirmed the efficacy and safety of these agents. Fetal ventricular tachycardia is an infrequent occurrence but can be associated with heart failure, hydrops, and sudden death. It is important to search for long QT syndrome. Transplacental administration of magnesium, propranolol, mexiletine, and lidocaine, alone or in combination, has been attempted for fetal ventricular tachycardia. Fetal complete atrioventricular block is caused by maternal autoantibodies or fetal congenital heart defects and is irreversible. There is currently no consensus on the indications for fetal treatment, including beta-sympathomimetics for bradyarrhythmia. Dexamethasone and intravenous immunoglobulin have been used to prevent or treat atrioventricular block and myocarditis, but recent studies have not shown the efficacy of these agents.</p>","PeriodicalId":16593,"journal":{"name":"Journal of Obstetrics and Gynaecology Research","volume":"51 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143554202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}