Obesity and Left Ventricular Function in American Indian Adolescents: Strong Heart Family Study.

IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Journal of Racial and Ethnic Health Disparities Pub Date : 2024-10-18 DOI:10.1007/s40615-024-02216-5
Joseph Burns, Keila N Lopez, Sara B Stephens, Jason F Deen
{"title":"Obesity and Left Ventricular Function in American Indian Adolescents: Strong Heart Family Study.","authors":"Joseph Burns, Keila N Lopez, Sara B Stephens, Jason F Deen","doi":"10.1007/s40615-024-02216-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Obesity is a known risk factor for developing cardiovascular disease (CVD). American Indian (AI) children have the highest obesity rates of all racial/ethnic groups in the United States (US). However, cardiometabolic health among AI adolescents is understudied. The purpose of this study was to describe the cardiometabolic characteristics of AI adolescents enrolled in the Strong Heart Family Study (SHFS), a longitudinal study of CVD from 12 AI communities, and associations with the development of abnormal left ventricular mass index (LVMI) and ejection fraction (EF).</p><p><strong>Study design: </strong>This study included AI youth ages 14-22 years. Primary outcome variables were depressed EF (< 55%) and abnormal LVMI at 6-year follow-up. The primary predictor variable was BMI. Covariates included sex, cholesterol levels, blood pressure, and hemoglobin A1c. Wilcoxon signed-rank test for matched pairs evaluated cardiometabolic trends over time. Stratified univariate logistic regression by obese/nonobese categories evaluated associations with depressed EF and abnormal LVMI.</p><p><strong>Results: </strong>There were 384 subjects, 58% of whom were overweight (n = 87) or obese (n = 122) at baseline. Among overweight/obese subjects, cholesterol and triglyceride levels were elevated. At 6-year follow-up, BMI increased while EF decreased among overweight/obese males, with 3.6 times the odds of having depressed EF (95% CI 1.22-10.98, p = 0.021) compared to normal-weight males. There were no significant cardiometabolic associations with LVMI.</p><p><strong>Conclusions: </strong>This is one of the largest longitudinal evaluations of CVD in AI adolescents. Concerning trends in BMI and depressed EF among AI males suggest the importance of culturally competent interventions to promote healthy weight and reduce cardiometabolic risk.</p>","PeriodicalId":16921,"journal":{"name":"Journal of Racial and Ethnic Health Disparities","volume":null,"pages":null},"PeriodicalIF":3.2000,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Racial and Ethnic Health Disparities","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s40615-024-02216-5","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives: Obesity is a known risk factor for developing cardiovascular disease (CVD). American Indian (AI) children have the highest obesity rates of all racial/ethnic groups in the United States (US). However, cardiometabolic health among AI adolescents is understudied. The purpose of this study was to describe the cardiometabolic characteristics of AI adolescents enrolled in the Strong Heart Family Study (SHFS), a longitudinal study of CVD from 12 AI communities, and associations with the development of abnormal left ventricular mass index (LVMI) and ejection fraction (EF).

Study design: This study included AI youth ages 14-22 years. Primary outcome variables were depressed EF (< 55%) and abnormal LVMI at 6-year follow-up. The primary predictor variable was BMI. Covariates included sex, cholesterol levels, blood pressure, and hemoglobin A1c. Wilcoxon signed-rank test for matched pairs evaluated cardiometabolic trends over time. Stratified univariate logistic regression by obese/nonobese categories evaluated associations with depressed EF and abnormal LVMI.

Results: There were 384 subjects, 58% of whom were overweight (n = 87) or obese (n = 122) at baseline. Among overweight/obese subjects, cholesterol and triglyceride levels were elevated. At 6-year follow-up, BMI increased while EF decreased among overweight/obese males, with 3.6 times the odds of having depressed EF (95% CI 1.22-10.98, p = 0.021) compared to normal-weight males. There were no significant cardiometabolic associations with LVMI.

Conclusions: This is one of the largest longitudinal evaluations of CVD in AI adolescents. Concerning trends in BMI and depressed EF among AI males suggest the importance of culturally competent interventions to promote healthy weight and reduce cardiometabolic risk.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
美国印第安青少年肥胖与左心室功能:强心家庭研究
目的:肥胖是心血管疾病(CVD)的一个已知风险因素。在美国所有种族/民族群体中,美国印第安人(AI)儿童的肥胖率最高。然而,美国印第安人青少年的心脏代谢健康状况却未得到充分研究。本研究旨在描述参加 "强心家庭研究"(Strong Heart Family Study,SHFS)的美国亚裔青少年的心脏代谢特征,以及与左心室质量指数(LVMI)和射血分数(EF)异常发展的关系:研究设计:研究对象包括 14-22 岁的亚裔青少年。研究设计:研究对象包括 14-22 岁的亚裔青少年:共有 384 名受试者,其中 58% 在基线时超重(87 人)或肥胖(122 人)。在超重/肥胖受试者中,胆固醇和甘油三酯水平升高。在6年的随访中,超重/肥胖男性的体重指数增加,而EF值下降,与正常体重男性相比,EF值下降的几率是正常男性的3.6倍(95% CI 1.22-10.98,p = 0.021)。结论:这是一项最大规模的纵向研究:这是针对人工智能青少年心血管疾病的最大规模纵向评估之一。美籍亚裔男性体重指数(BMI)和心房颤动指数(EF)下降的趋势表明,必须采取符合当地文化的干预措施,以促进健康体重和降低心脏代谢风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Journal of Racial and Ethnic Health Disparities
Journal of Racial and Ethnic Health Disparities PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
7.30
自引率
5.10%
发文量
263
期刊介绍: Journal of Racial and Ethnic Health Disparities reports on the scholarly progress of work to understand, address, and ultimately eliminate health disparities based on race and ethnicity. Efforts to explore underlying causes of health disparities and to describe interventions that have been undertaken to address racial and ethnic health disparities are featured. Promising studies that are ongoing or studies that have longer term data are welcome, as are studies that serve as lessons for best practices in eliminating health disparities. Original research, systematic reviews, and commentaries presenting the state-of-the-art thinking on problems centered on health disparities will be considered for publication. We particularly encourage review articles that generate innovative and testable ideas, and constructive discussions and/or critiques of health disparities.Because the Journal of Racial and Ethnic Health Disparities receives a large number of submissions, about 30% of submissions to the Journal are sent out for full peer review.
期刊最新文献
Disparities in Patient Portal Activation and Usage at a Large Pediatric Academic Institution. Intersecting Epidemics: Examining the Impact of Internalized Homophobia and Depression Symptoms on HIV Testing Through a Suicide Syndemic Among Young Black Men Who Have Sex with Men. Socioeconomic Status, Social Support, and Quality of Life Among Black Adults. Bridging the Gap: Culturally Responsive Strategies for NIH Trial Recruitment. A Review of the Public Health Literature Examining the Roles of Socioeconomic Status and Race/Ethnicity on Health Outcomes in the United States.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1