Agreement between the EWGSOP2 and SDOC consensuses for sarcopenia in patients receiving hemodialysis: Findings of a cross sectional analysis from the SARC-HD study.

IF 2.1 4区医学 Q3 NUTRITION & DIETETICS Nutrition in Clinical Practice Pub Date : 2024-10-15 DOI:10.1002/ncp.11227

Marvery P Duarte, Otávio T Nóbrega, Victor M Baião, Fábio A Vieira, Jacqueline S Monteiro, Marina S Pereira, Luis F Pires, Gabrielle G Queiroz, Mauro J Silva, Maryanne Z C Silva, Fabiana L Costa, Henrique S Disessa, Clara C Rosa, Henrique L Monteiro, Dario R Mondini, Luiz R Medina, Flávio I Nishimaru, Maria G Rosa, Marco C Uchida, Rodrigo R Krug, Paulo R Moreira, Bruna M Sant'Helena, Daiana C Bundchen, Christine D Molin, Laura Polo, Maristela Bohlke, Caroline S Mendes, Antônia S Almeida, Angélica N Adamoli, Catiussa Colling, Ricardo M Lima, Antônio J Inda-Filho, Aparecido P Ferreira, Carla M Avesani, Barbara P Vogt, Maycon M Reboredo, Heitor S Ribeiro

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Abstract

Background: Differences in definitions and operational diagnoses for sarcopenia create difficulties in understanding the epidemiology of the disease. We examined the prevalences of sarcopenia using the revised European Working Group on Sarcopenia in Older People (EWGSOP2) and the Sarcopenia Definitions and Outcomes Consortium (SDOC) consensuses and analyzed their level of agreement in patients receiving hemodialysis.

Methods: Data from the SARCopenia trajectories and associations with clinical outcomes in patients receiving hemodialysis (SARC-HD) multicenter study in Brazil were analyzed. Muscle strength was assessed using handgrip strength, muscle mass by calf circumference, and physical performance by the 4-m gait speed test. Sarcopenia was diagnosed according to both the EWGSOP2 (low muscle strength plus low muscle mass) and the SDOC (low muscle strength plus low physical performance). The Cohen kappa statistic was used to determine the level of agreement between the consensuses.

Results: 838 patients (57.8 ± 15.0 years; 61% men) from 19 dialysis units were included. We found similar prevalences of sarcopenia between the consensuses (EWGSOP2, n = 128, 15.3%; SDOC, n = 105, 12.5%) but with weak agreement (50 of 233 patients, 21.5%; κ = 0.34, 95% CI 0.25-0.43). Agreement was also weak within age categories (≥60 years, κ = 0.34; <60 years, κ = 0.15; both P < 0.001). Of the 51 patients diagnosed by the EWGSOP2 criterion as having severe sarcopenia, all but 1 (98.0%) met the SDOC criterion for sarcopenia (κ = 0.61, 95% CI 0.52-0.70). Low muscle strength was more frequently diagnosed using the SDOC than with the EWGSOP2 (52.3% vs 25.9%).

Conclusion: We found a weak agreement between the EWGSOP2 and SDOC consensuses for the diagnosis of sarcopenia in patients receiving hemodialysis. Although still weak, agreement was marginally better for older patients. These findings highlight the importance of a global and standardized conceptual diagnosis of sarcopenia.

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血液透析患者肌少症的 EWGSOP2 和 SDOC 一致性：SARC-HD 研究的横断面分析结果。

背景：由于对肌肉疏松症的定义和操作诊断存在差异，因此在了解该疾病的流行病学方面存在困难。我们使用修订后的欧洲老年人肌肉疏松症工作组（EWGSOP2）和肌肉疏松症定义与结果联盟（SDOC）共识研究了肌肉疏松症的患病率，并分析了它们在血液透析患者中的一致程度：方法：分析了来自巴西血液透析患者 Sarcopenia 轨迹及与临床结果的关联（SARC-HD）多中心研究的数据。肌肉力量通过手握力进行评估，肌肉质量通过小腿围度进行评估，体能通过 4 米步速测试进行评估。根据 EWGSOP2（低肌力加低肌肉质量）和 SDOC（低肌力加低体能）诊断出肌肉疏松症。科恩卡帕统计法用于确定共识之间的一致程度：共纳入了来自 19 个透析单位的 838 名患者（57.8 ± 15.0 岁；61% 为男性）。我们发现各共识之间的肌少症患病率相似（EWGSOP2，n = 128，15.3%；SDOC，n = 105，12.5%），但一致性较弱（233 位患者中有 50 位，21.5%；κ = 0.34，95% CI 0.25-0.43）。不同年龄段之间的一致性也较弱（≥60 岁，κ = 0.34；结论：EWG 测量的一致性较弱：我们发现 EWGSOP2 和 SDOC 在诊断血液透析患者肌少症方面的一致性较弱。尽管一致性仍然较弱，但老年患者的一致性略好。这些发现强调了对肌肉疏松症进行全面、标准化概念诊断的重要性。

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来源期刊

Nutrition in Clinical Practice 医学-营养学

CiteScore

6.00

自引率

9.70%

发文量

128

审稿时长

3 months

期刊介绍： NCP is a peer-reviewed, interdisciplinary publication that publishes articles about the scientific basis and clinical application of nutrition and nutrition support. NCP contains comprehensive reviews, clinical research, case observations, and other types of papers written by experts in the field of nutrition and health care practitioners involved in the delivery of specialized nutrition support. This journal is a member of the Committee on Publication Ethics (COPE).