{"title":"AI driven interpretable deep learning based fetal health classification","authors":"Gazala Mushtaq, Veningston K","doi":"10.1016/j.slast.2024.100206","DOIUrl":null,"url":null,"abstract":"<div><div>In this study, a deep learning model is proposed for the classification of fetal health into 3 categories: Normal, suspect, and pathological. The primary objective is to utilize the power of deep learning to improve the efficiency and effectiveness of diagnostic processes. A deep neural network (DNN) model is proposed for fetal health analysis using data obtained from Cardiotocography (CTG). A dataset containing 21 attributes is used to carry out this work. The model incorporates multiple hidden layers, augmented with batch normalization and dropout layers for improved generalization. This study assesses the model's interpretation ability in fetal health classification using explainable deep learning. This enhances transparency in decision-making of the classifier model by leveraging feature importance and feature saliency analysis, fostering trust and facilitating the clinical adoption of fetal health assessments. Our proposed model demonstrates a remarkable performance with 0.99 accuracy, 0.93 sensitivity, 0.93 specificity, 0.96 AUC, 0.93 precision, and 0.93 F1 scores in classifying fetal health. We also performed comparative analysis with six other models including Logistic Regression, KNN, SVM, Naive Bayes, Random Forest, and Gradient Boosting to assess and compare the effectiveness of our model and the accuracies of 0.89, 0.88, 0.90, 081, 0.93, and 0.93 were achieved respectively by these baseline models. The results revealed that our proposed model outperformed all the baseline models in terms of accuracy. This indicates the potential of deep learning in improving fetal health assessment and contributing to the field of obstetrics by providing a robust tool for early risk detection.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"29 6","pages":"Article 100206"},"PeriodicalIF":2.5000,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SLAS Technology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2472630324000888","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
In this study, a deep learning model is proposed for the classification of fetal health into 3 categories: Normal, suspect, and pathological. The primary objective is to utilize the power of deep learning to improve the efficiency and effectiveness of diagnostic processes. A deep neural network (DNN) model is proposed for fetal health analysis using data obtained from Cardiotocography (CTG). A dataset containing 21 attributes is used to carry out this work. The model incorporates multiple hidden layers, augmented with batch normalization and dropout layers for improved generalization. This study assesses the model's interpretation ability in fetal health classification using explainable deep learning. This enhances transparency in decision-making of the classifier model by leveraging feature importance and feature saliency analysis, fostering trust and facilitating the clinical adoption of fetal health assessments. Our proposed model demonstrates a remarkable performance with 0.99 accuracy, 0.93 sensitivity, 0.93 specificity, 0.96 AUC, 0.93 precision, and 0.93 F1 scores in classifying fetal health. We also performed comparative analysis with six other models including Logistic Regression, KNN, SVM, Naive Bayes, Random Forest, and Gradient Boosting to assess and compare the effectiveness of our model and the accuracies of 0.89, 0.88, 0.90, 081, 0.93, and 0.93 were achieved respectively by these baseline models. The results revealed that our proposed model outperformed all the baseline models in terms of accuracy. This indicates the potential of deep learning in improving fetal health assessment and contributing to the field of obstetrics by providing a robust tool for early risk detection.
期刊介绍:
SLAS Technology emphasizes scientific and technical advances that enable and improve life sciences research and development; drug-delivery; diagnostics; biomedical and molecular imaging; and personalized and precision medicine. This includes high-throughput and other laboratory automation technologies; micro/nanotechnologies; analytical, separation and quantitative techniques; synthetic chemistry and biology; informatics (data analysis, statistics, bio, genomic and chemoinformatics); and more.