Role of Surgery in Vestibular Schwannoma following prior Stereotactic Radiosurgery.

IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI:10.47391/JPMA.24-84
Zanib Javed, M Shahzad Shamim
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Abstract

Stereotactic radiosurgery (SRS) is widely used for treating vestibular schwannoma (VS), offering high tumour control rates, especially in small to medium-sized tumours. However, a subset of patients experiences SRS failure, requiring subsequent salvage microsurgery (MS). The primary reason for salvage surgery is continued tumour growth, but other causes include symptom progression and cystic enlargement. Salvage surgery is more challenging due to increased tumour adhesion to critical structures, resulting in higher complication rates, particularly for facial nerve preservation. Studies suggest subtotal resection may offer better outcomes than gross total resection in terms of facial nerve function, though treatment remains complex and outcomes vary.

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立体定向放射外科手术在前庭神经丛瘤中的作用。
立体定向放射外科(SRS)被广泛用于治疗前庭裂隙瘤(VS),肿瘤控制率很高,尤其是中小型肿瘤。然而,也有一部分患者的 SRS 治疗失败,需要进行显微外科挽救手术(MS)。挽救手术的主要原因是肿瘤继续生长,其他原因还包括症状进展和囊肿增大。由于肿瘤与重要结构的粘连增加,挽救手术更具挑战性,因此并发症发生率较高,尤其是面神经的保留。研究表明,就面神经功能而言,次全切除术可能比全切术效果更好,但治疗仍然很复杂,效果也各不相同。
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来源期刊
CiteScore
1.10
自引率
11.10%
发文量
983
审稿时长
3-6 weeks
期刊介绍: Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.
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