Potential determinants of early discontinuation of Etonogestrel implant: a cohort prospective study.

IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI:10.47391/JPMA-BAGH-16-24
Zeena Helmi
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Abstract

Objective: To assess the frequency of early discontinuation of Implanon as a method of contraception.

Methods: The cohort prospective study was conducted at the Obstetrics and Gynaecology Department, Al-Yarmouk Teaching Hospital, Baghdad, Iraq from January 2017 to January 2021, after approval from the ethics review committee of the College of Medicine, Al-Mustansiriyha University, Bghadad, Iraq, and comprised women of childbearing age seeking long-acting contraception. The participants received Implanon, an etonorgestril implant, under local anaesthesia, and were followed up for 12 months for possible side effects. Data was analysed using SPSS 26.

Results: There were 115 women with mean age 29.8±6 years (range: 15-44 years) and mean body mass index 27±4.9 kg/m2. Early discontinuation of the plant was done by 32(27.8%) subjects, and the overall incidence of early Implanon removal per 1,000 women per month was 14.47 (95% confidence interval: 10.24-20.47). Lower body mass index, dizziness and insertion-site side effects were the potential determinants of early discontinuation (p<0.05).

Conclusions: More than a quarter of the sample opted for early Implanon discontinuation. Low body mass index, dizziness and insertion-site side effects were potential determinants of early removal.

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艾托孕烯植入物提前停用的潜在决定因素:一项前瞻性队列研究。
目的评估提前停用 Implanon 避孕药的频率:经伊拉克巴格达 Al-Mustansiriyha 大学医学院伦理审查委员会批准,于 2017 年 1 月至 2021 年 1 月在伊拉克巴格达 Al-Yarmouk 教学医院妇产科开展了一项队列前瞻性研究,研究对象包括寻求长效避孕方法的育龄妇女。参与者在局部麻醉下接受了 Implanon(一种依托诺孕酮植入剂),并接受了 12 个月的随访,以了解可能出现的副作用。数据使用 SPSS 26 进行分析:115 名妇女的平均年龄为(29.8±6)岁(15-44 岁),平均体重指数为(27±4.9)千克/平方米。32(27.8%)名受试者提前停用了该避孕药,每千名妇女每月提前取出 Implanon 的总发生率为 14.47(95% 置信区间:10.24-20.47)。较低的体重指数、头晕和插入部位的副作用是提前停用的潜在决定因素(P结论:超过四分之一的样本选择提前停用 Implanon。低体重指数、头晕和插入部位的副作用是提前取出的潜在决定因素。
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来源期刊
CiteScore
1.10
自引率
11.10%
发文量
983
审稿时长
3-6 weeks
期刊介绍: Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.
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