CT perfusion imaging in aneurysmal subarachnoid hemorrhage. State of the art.

Frontiers in radiology Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI:10.3389/fradi.2024.1445676
Valentina Elisabetta Lolli, Adrien Guenego, Niloufar Sadeghi, Lise Jodaitis, Boris Lubicz, Fabio Silvio Taccone, Elisa Gouvea Bogossian
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Abstract

CT perfusion (CTP) images can be easily and rapidly obtained on all modern CT scanners and have become part of the routine imaging protocol of patients with aneurysmal subarachnoid haemorrhage (aSAH). There is a growing body of evidence supporting the use of CTP imaging in these patients, however, there are significant differences in the software packages and methods of analysing CTP. In. addition, no quantitative threshold values for tissue at risk (TAR) have been validated in this patients' population. Here we discuss the contribution of the technique in the identification of patients at risk of aSAH-related delayed cerebral ischemia (DCI) and in the assessment of the response to endovascular rescue therapy (ERT). We also address the limitations and pitfalls of automated CTP postprocessing that are specific to aSAH patients as compared to acute ischemic stroke (AIS).

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动脉瘤性蛛网膜下腔出血的 CT 灌注成像。最新技术。
CT 灌注(CTP)图像可在所有现代 CT 扫描仪上轻松快速地获得,并已成为动脉瘤性蛛网膜下腔出血(aSAH)患者常规成像方案的一部分。越来越多的证据支持在这些患者中使用 CTP 成像,然而,在分析 CTP 的软件包和方法上存在很大差异。此外,在这类患者中还没有对风险组织(TAR)的定量阈值进行过验证。在此,我们将讨论该技术在识别与 ASAH 相关的延迟性脑缺血(DCI)风险患者和评估血管内抢救疗法(ERT)反应方面的贡献。我们还讨论了与急性缺血性卒中(AIS)相比,自动 CTP 后处理对 aSAH 患者所特有的局限性和隐患。
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