Summary Analysis of National Surveillance on Kashin-Beck Disease from 1990 to 2023.

Si Lu Cui, Hui Liu, Jun Rui Pei, Jia Xin Li, Zhe Jiao, Qing Deng, Ning Liu, Yan Hong Cao, Jun Yu
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Abstract

Objective: To analyze the epidemiological characteristics and epidemic situation of children with Kashin-Beck disease (KBD) in China, and provide the basis for formulating prevention and control measures.

Methods: Fixed-point monitoring, moving-point monitoring, and full coverage of monitoring were promoted successively from 1990 to 2023. Some children (7-12 years old) underwent clinical and right-hand X-ray examinations every year. According to the KBD diagnosis criteria, clinical and X-ray assessments were used to confirm the diagnosis.

Results: In 1990, the national KBD detectable rate was 21.01%. X-ray detection decreased to below 10% in 2003 and below 5% in 2007. Between 2010 and 2018, the prevalence of KBD in children was less than 0.4%, which fluctuated at a low level, and has decreased to 0% since 2019. Spatial epidemiological analysis indicated a spatial clustering of adult patients prevalence rate in the KBD areas.

Conclusion: The evaluation results of the elimination of KBD in China over the last 5 years showed that all villages in the monitored areas have reached the elimination standard. While the adult KBD patients still need for policy consideration and care.

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1990 年至 2023 年全国卡欣贝克病监测情况汇总分析。
摘要分析中国儿童卡介苗(KBD)的流行病学特征和疫情形势,为制定防控措施提供依据:方法:从 1990 年至 2023 年,先后开展定点监测、定点移动监测和全覆盖监测。每年对部分儿童(7-12 岁)进行临床和右手 X 光检查。根据 KBD 诊断标准,通过临床和 X 光评估进行确诊:1990年,全国KBD检出率为21.01%。2003 年,X 射线检出率降至 10%以下,2007 年降至 5%以下。2010年至2018年,儿童KBD患病率低于0.4%,在低水平波动,2019年起降至0%。空间流行病学分析表明,成人患者患病率在KBD地区存在空间聚集现象。结论:中国近5年消除KBD的评估结果显示,监测地区的所有村庄均已达到消除标准。结论:过去 5 年的评估结果表明,中国监测地区的所有村庄均已达到消除标准,但仍需从政策角度考虑和关注成人卡介苗患者。
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