Effects of multicomponent exercise on frailty status and physical function in frail older adults: A meta-analysis and systematic review

IF 3.9 Experimental gerontology Pub Date : 2024-10-21 DOI:10.1016/j.exger.2024.112604

Xinyu Yang , Shasha Li , Lingfen Xu , Haibing Liu , Yue Li , Xiaofang Song , Jianyi Bao , Shufang Liao , Yingxue Xi , Guojing Guo

{"title":"Effects of multicomponent exercise on frailty status and physical function in frail older adults: A meta-analysis and systematic review","authors":"Xinyu Yang , Shasha Li , Lingfen Xu , Haibing Liu , Yue Li , Xiaofang Song , Jianyi Bao , Shufang Liao , Yingxue Xi , Guojing Guo","doi":"10.1016/j.exger.2024.112604","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>The study aimed to carry out a systematic review and meta-analysis to explore the effects of multicomponent exercise on frailty status and physical function in frail older adults.</div></div><div><h3>Design</h3><div>A systematic review and meta-analysis.</div></div><div><h3>Setting and participants</h3><div>Older adults aged ≥60 years diagnosed with frailty using the Frailty Assessment Tool.</div></div><div><h3>Methods</h3><div>PubMed, EMBASE, Web of Science, Cochrane Library, CNKI, and Wanfang were searched from inception to March 10, 2024. Two reviewers independently screened and selected the publications, extracted the data, and assessed risk of bias. This study included randomized controlled trials and quasi-experimental designs. Review Manager 5.4 was used for data analysis.</div></div><div><h3>Results</h3><div>Twenty-eight randomized controlled trials with 4857 older adults were included. Multicomponent exercise significantly improved frailty status (SMD = −1.40, 95 % CI:−2.05 to −0.75, P < .05) and had a significant impact on physical function (muscle strength: SMD = 0.31, 95 % CI: 0.01–0.61, P < .05; gait speed: SMD = 0.27, 95 % CI: 0.02–0.52, P < .001; balance: SMD = 0.27, 95 % CI: 0.05–0.49, P = .02; Short Physical Performance Battery [SPPB]: SMD = 1.03, 95 % CI: 0.65–1.42, P < .001; and Timed Up and Go [TUG]: SMD = −3.05, 95 % CI: −3.90 to −2.19, P < .001). Subgroup analysis suggested that a 12-week duration is optimal for multicomponent exercise interventions, demonstrating significantly greater effectiveness in hospital compared with out-of-hospital.</div></div><div><h3>Conclusions</h3><div>Multicomponent exercise intervention can improve frailty status in older adults and promote enhancement of physical functional abilities (muscle strength, gait speed, balance, SPPB, and TUG). Therefore, a possible protective effect of multicomponent exercise in frailty older adults is suggested.</div></div>","PeriodicalId":94003,"journal":{"name":"Experimental gerontology","volume":"197 ","pages":"Article 112604"},"PeriodicalIF":3.9000,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental gerontology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S053155652400250X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives

The study aimed to carry out a systematic review and meta-analysis to explore the effects of multicomponent exercise on frailty status and physical function in frail older adults.

Design

A systematic review and meta-analysis.

Setting and participants

Older adults aged ≥60 years diagnosed with frailty using the Frailty Assessment Tool.

Methods

PubMed, EMBASE, Web of Science, Cochrane Library, CNKI, and Wanfang were searched from inception to March 10, 2024. Two reviewers independently screened and selected the publications, extracted the data, and assessed risk of bias. This study included randomized controlled trials and quasi-experimental designs. Review Manager 5.4 was used for data analysis.

Results

Twenty-eight randomized controlled trials with 4857 older adults were included. Multicomponent exercise significantly improved frailty status (SMD = −1.40, 95 % CI:−2.05 to −0.75, P < .05) and had a significant impact on physical function (muscle strength: SMD = 0.31, 95 % CI: 0.01–0.61, P < .05; gait speed: SMD = 0.27, 95 % CI: 0.02–0.52, P < .001; balance: SMD = 0.27, 95 % CI: 0.05–0.49, P = .02; Short Physical Performance Battery [SPPB]: SMD = 1.03, 95 % CI: 0.65–1.42, P < .001; and Timed Up and Go [TUG]: SMD = −3.05, 95 % CI: −3.90 to −2.19, P < .001). Subgroup analysis suggested that a 12-week duration is optimal for multicomponent exercise interventions, demonstrating significantly greater effectiveness in hospital compared with out-of-hospital.

Conclusions

Multicomponent exercise intervention can improve frailty status in older adults and promote enhancement of physical functional abilities (muscle strength, gait speed, balance, SPPB, and TUG). Therefore, a possible protective effect of multicomponent exercise in frailty older adults is suggested.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

多成分运动对体弱老年人虚弱状况和身体功能的影响：荟萃分析和系统综述。

研究目的本研究旨在进行系统回顾和荟萃分析，探讨多成分运动对体弱老年人的虚弱状态和身体功能的影响：设计：系统综述和荟萃分析：方法：方法：检索了从开始到2024年3月10日的PubMed、EMBASE、Web of Science、Cochrane Library、CNKI和万方数据库。由两名审稿人独立筛选出版物、提取数据并评估偏倚风险。本研究包括随机对照试验和准实验设计。使用Review Manager 5.4进行数据分析：结果：共纳入了 28 项随机对照试验，4857 名老年人参加了试验。多组分运动能明显改善虚弱状态（SMD = -1.40, 95 % CI:-2.05 to -0.75，P 结论：多组分运动干预能改善虚弱状态：多组分运动干预可以改善老年人的虚弱状况，促进身体功能能力（肌肉力量、步态速度、平衡能力、SPPB 和 TUG）的提高。因此，多成分运动可能对虚弱的老年人有保护作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊