Temperature-compensated optical fiber sensor for urea detection based on the femtosecond laser-inscribed process

IF 8 1区 化学 Q1 CHEMISTRY, ANALYTICAL Sensors and Actuators B: Chemical Pub Date : 2024-10-23 DOI:10.1016/j.snb.2024.136795
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Abstract

This study demonstrates a low crosstalk temperature-compensated fiber-based urea sensor based on the hybridization of surface plasmon resonance (SPR) and Mach-Zehnder interferometer (MZI). In this sensing structure, an inscribed waveguide and a semi-open cavity are processed by a femtosecond laser in an optical fiber to excite an SPR signal sensitive to refractive index (RI) and an MZI signal highly sensitive to temperature. Based on the temperature detected by the MZI, the influence of temperature on the SPR signal’s RI detection can be calculated and compensated for using a sensitivity matrix. Based on this precise RI detection of the SPR signal, we have achieved selective urea detection by bio-functionalizing the sensor surface using the urease self-assembly method. The sensitivity and limit of detection for urea are 7.98 (nm/mmol/L) and 0.13 mmol/L, respectively, which are better than those in previous studies. Compared to previous temperature compensation studies, this SPR + MZI sensing method using femtosecond laser processing significantly improves the temperature sensitivity of the MZI signal, which reduces crosstalk and ensures a sufficient working range for the SPR signal. Therefore, this sensor is crucial for advancing high-precision temperature compensation detection, high-sensitivity biological detection, and the future application of the femtosecond laser technology.
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基于飞秒激光刻蚀工艺的尿素检测用温度补偿光纤传感器
本研究展示了一种基于表面等离子体共振(SPR)和马赫-泽恩德干涉仪(MZI)杂交技术的低串扰温度补偿光纤尿素传感器。在这一传感结构中,光纤中的飞秒激光器对刻入波导和半开放腔进行处理,以激发对折射率(RI)敏感的 SPR 信号和对温度高度敏感的 MZI 信号。根据 MZI 检测到的温度,可以计算出温度对 SPR 信号的 RI 检测的影响,并利用灵敏度矩阵进行补偿。基于这种精确的 SPR 信号 RI 检测,我们利用尿素酶自组装方法对传感器表面进行生物功能化处理,实现了选择性尿素检测。尿素的灵敏度和检测限分别为 7.98(nm/mmol/L)和 0.13 mmol/L,均优于以往的研究。与以往的温度补偿研究相比,这种利用飞秒激光处理的 SPR + MZI 传感方法大大提高了 MZI 信号的温度灵敏度,从而减少了串扰,确保了 SPR 信号有足够的工作范围。因此,这种传感器对于推进高精度温度补偿检测、高灵敏度生物检测以及飞秒激光技术的未来应用至关重要。
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来源期刊
Sensors and Actuators B: Chemical
Sensors and Actuators B: Chemical 工程技术-电化学
CiteScore
14.60
自引率
11.90%
发文量
1776
审稿时长
3.2 months
期刊介绍: Sensors & Actuators, B: Chemical is an international journal focused on the research and development of chemical transducers. It covers chemical sensors and biosensors, chemical actuators, and analytical microsystems. The journal is interdisciplinary, aiming to publish original works showcasing substantial advancements beyond the current state of the art in these fields, with practical applicability to solving meaningful analytical problems. Review articles are accepted by invitation from an Editor of the journal.
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