Advancing ketamine in the treatment hierarchy for refractory depression

Kabir Nigam, Franklin King IV, Fernando Espi Forcen
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Abstract

Evidence indicates that ketamine is highly effective, has a lower side effect profile and is better tolerated compared to many augmentation strategies for refractory depression. This, combined with data on psychiatric treatment outcome mediators, suggests that earlier intervention with ketamine could improve outcomes for patients suffering from refractory depression.

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推进氯胺酮在难治性抑郁症治疗层次中的应用
有证据表明,与许多治疗难治性抑郁症的增强策略相比,氯胺酮疗效高、副作用小、耐受性好。这一点与精神科治疗结果介导因素的数据相结合,表明尽早使用氯胺酮进行干预可改善难治性抑郁症患者的治疗结果。
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