Hiddo J.L. Heerspink, Meg Jardine, Donald E. Kohan, Richard A. Lafayette, Adeera Levin, Adrian Liew, Hong Zhang, Amit Lodha, Todd Gray, Yi Wang, Ronny Renfurm, and Jonathan Barrattthe ALIGN Study Investigators*From the Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands (H.J.L.H.), the National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney (M.J.), the Division of Nephrology, University of Utah Health, Salt Lake City (D.E.K.), Stanford University, Stanford, CA (R.A.L.), the University of British Columbia, Vancouver, Canada (A. Levin), Mount Elizabeth Novena Hospital, Singapore (A. Liew), Peking University First Hospital, Beijing (H.Z.), Chinook Therapeutics, Seattle (T.G.), Novartis, East Hanover, NJ (A. Lodha, Y.W.), Novartis, Basel, Switzerland (R.R.), and the University of Leicester, Leicester, United Kingdom (J.B.).
{"title":"Atrasentan in Patients with IgA Nephropathy","authors":"Hiddo J.L. Heerspink, Meg Jardine, Donald E. Kohan, Richard A. Lafayette, Adeera Levin, Adrian Liew, Hong Zhang, Amit Lodha, Todd Gray, Yi Wang, Ronny Renfurm, and Jonathan Barrattthe ALIGN Study Investigators*From the Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands (H.J.L.H.), the National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney (M.J.), the Division of Nephrology, University of Utah Health, Salt Lake City (D.E.K.), Stanford University, Stanford, CA (R.A.L.), the University of British Columbia, Vancouver, Canada (A. Levin), Mount Elizabeth Novena Hospital, Singapore (A. Liew), Peking University First Hospital, Beijing (H.Z.), Chinook Therapeutics, Seattle (T.G.), Novartis, East Hanover, NJ (A. Lodha, Y.W.), Novartis, Basel, Switzerland (R.R.), and the University of Leicester, Leicester, United Kingdom (J.B.).","doi":"10.1056/nejmoa2409415","DOIUrl":null,"url":null,"abstract":"Patients with IgA nephropathy and severe proteinuria have a high lifetime risk of kidney failure. The efficacy and safety of the selective endothelin type A receptor antagonist atrasentan in reduci...","PeriodicalId":54725,"journal":{"name":"New England Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":96.2000,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"New England Journal of Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1056/nejmoa2409415","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Patients with IgA nephropathy and severe proteinuria have a high lifetime risk of kidney failure. The efficacy and safety of the selective endothelin type A receptor antagonist atrasentan in reduci...
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