Sonda Jallouli, Rami Maaloul, Sameh Ghroubi, Rim Kammoun, Mariem Damak, Salma Sakka, Tarak Driss, Giovanni de Marco, Chokri Mhiri, Mohamed Habib Elleuch, Walid Feki, Omar Hammouda
{"title":"Benefits of self-paced concurrent training on lung function, cardiopulmonary fitness and fatigue perception in patients with multiple sclerosis.","authors":"Sonda Jallouli, Rami Maaloul, Sameh Ghroubi, Rim Kammoun, Mariem Damak, Salma Sakka, Tarak Driss, Giovanni de Marco, Chokri Mhiri, Mohamed Habib Elleuch, Walid Feki, Omar Hammouda","doi":"10.1080/17582024.2024.2404385","DOIUrl":null,"url":null,"abstract":"<p><p><b>Aim:</b> Studying the effects of self-paced concurrent high-intensity interval training and resistance training (HIIT-RT) on respiratory function, cardiopulmonary fitness and fatigue perception in patients with multiple sclerosis (PwMS).<b>Methods:</b> Twenty-three PwMS were randomized into a 12-week training group (three times per week) (TG, n = 11) or a control group (CG, n = 12). Lung function (spirometry), aerobic capacity (graded cardiopulmonary-exercise-testing) and perceived fatigue (Fatigue Severity Scale (FSS)) were evaluated pre- and post-intervention.<b>Results:</b> The forced vital capacity (<i>p</i> = 0.036, Hedges'g (g) = 0.93), forced expiratory time (<i>p</i> = 0.045, g = 0.88), peak expiratory flow (<i>p</i> = 0.043, g = 0.89) increased in TG compared with CG. The TG showed an increase in peak aerobic power (<i>p</i> = 0.004, g = 1.34) and peak oxygen uptake (<i>p</i> < 0.001, g = 2.58) compared with CG. There was a decrease in ventilatory equivalent for carbon dioxide (<i>p</i> = 0.02, g = 1.02) and FSS scores (<i>p</i> < 0.001, g = 1.72) in TG comparatively with CG.<b>Conclusion:</b> 12-week self-paced HIIT-RT enhanced lung function as well as aerobic fitness, and alleviated fatigue perception in PwMS.</p>","PeriodicalId":19114,"journal":{"name":"Neurodegenerative disease management","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524201/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurodegenerative disease management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/17582024.2024.2404385","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/22 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: Studying the effects of self-paced concurrent high-intensity interval training and resistance training (HIIT-RT) on respiratory function, cardiopulmonary fitness and fatigue perception in patients with multiple sclerosis (PwMS).Methods: Twenty-three PwMS were randomized into a 12-week training group (three times per week) (TG, n = 11) or a control group (CG, n = 12). Lung function (spirometry), aerobic capacity (graded cardiopulmonary-exercise-testing) and perceived fatigue (Fatigue Severity Scale (FSS)) were evaluated pre- and post-intervention.Results: The forced vital capacity (p = 0.036, Hedges'g (g) = 0.93), forced expiratory time (p = 0.045, g = 0.88), peak expiratory flow (p = 0.043, g = 0.89) increased in TG compared with CG. The TG showed an increase in peak aerobic power (p = 0.004, g = 1.34) and peak oxygen uptake (p < 0.001, g = 2.58) compared with CG. There was a decrease in ventilatory equivalent for carbon dioxide (p = 0.02, g = 1.02) and FSS scores (p < 0.001, g = 1.72) in TG comparatively with CG.Conclusion: 12-week self-paced HIIT-RT enhanced lung function as well as aerobic fitness, and alleviated fatigue perception in PwMS.