Combined Epiretinal Proliferation and Internal Limiting Membrane Inverted Flap for the Treatment of Large Macular Holes.

Q2 Medicine Vision (Switzerland) Pub Date : 2024-10-19 DOI:10.3390/vision8040063

Nikolaos Dervenis, Iordanis Vagiakis, Elena P Papadopoulou, Panagiotis Dervenis, Teresa Sandinha

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Abstract

We are presenting a new method for the treatment of large macular holes (MHs) with the use of an inverted flap consisting of both internal limiting membrane (ILM) and epiretinal proliferation (EP). A prospective interventional case series was conducted from September 2021 to January 2023. MH patients with coexistent EP visualized preoperatively in macula optical coherence tomography and with a MHs minimum linear diameter larger than 400 microns underwent standard pars plana vitrectomy with the creation of an inverted petaloid flap (consisting of both ILM and EP) and gas tamponade. Sixteen eyes were included in our case series. MHs closure was successful in all the eyes with a single procedure. The preoperative minimum linear diameter was 707.63 (±164.02 μm), and the preoperative best corrected visual acuity was 1.11 ± 0.52. The postoperative BCVA was 0.51 ± 0.20 (p = 0.01) at 6 weeks postoperatively, and the final BCVA was 0.45 ± 0.20 (p = 0.008). EP can be safely combined with ILM for the creation of an inverted, petaloid flap to cover and facilitate the closure of large MHs.

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联合视网膜外增殖和内限制膜翻转瓣治疗大黄斑孔。

我们提出了一种治疗大黄斑孔（MHs）的新方法，即使用由内缘膜（ILM）和视网膜外增殖（EP）组成的倒置瓣。2021 年 9 月至 2023 年 1 月期间进行了一项前瞻性介入病例系列研究。术前通过黄斑光学相干断层扫描观察到同时存在EP且MHs最小线性直径大于400微米的MH患者接受了标准的平视玻璃体切除术，同时制作了一个倒置的花瓣（由ILM和EP组成）并进行了气体填塞。我们的病例系列包括 16 只眼睛。所有眼球的MHs闭合都是一次手术成功。术前最小线性直径为 707.63 (±164.02 μm)，术前最佳矫正视力为 1.11 ± 0.52。术后 6 周，BCVA 为 0.51 ± 0.20（p = 0.01），最终 BCVA 为 0.45 ± 0.20（p = 0.008）。EP可以安全地与ILM相结合，用于制作倒置的花瓣瓣，以覆盖并促进大面积MH的闭合。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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