Macrophage GPNMB-mediated cardiac repair

IF 9.4 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Nature cardiovascular research Pub Date : 2024-10-25 DOI:10.1038/s44161-024-00559-0
Jennifer J. Hill
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Abstract

Glycoprotein non-metastatic melanoma protein B (GPNMB) is produced by macrophages and mediates cardiac repair through direct interaction with an orphan G-protein-coupled receptor, GPR39.

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巨噬细胞 GPNMB 介导的心脏修复
糖蛋白非转移性黑色素瘤蛋白 B(GPNMB)由巨噬细胞产生,通过与孤儿 G 蛋白偶联受体 GPR39 直接相互作用,介导心脏修复。
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