{"title":"Early history of clinical application of photosensitizing drugs in photodynamic therapy (PDT) of portwine stain (PWS) birthmarks","authors":"Kaihua Yuan , Zheng Huang","doi":"10.1016/j.pdpdt.2024.104383","DOIUrl":null,"url":null,"abstract":"<div><div>It has been known for two decades that vascular acting PDT can be used as an alternative in the treatment of portwine stain (PWS) birthmarks. The modality is only used in China at the moment and an expert consensus has been published this year. A recent review article in Lasers in Surgery and Medicine summarized the available evidence based on PubMed records of PWS treatment using pulsed dye laser (PDL) and HMME-PDT. The authors observed that HMME-PDT has emerged as the first choice for PWS treatment, particularly for young children, in many major hospitals in China. The authors also raised questions on ethics of several Chinese reports. This correspondence addresses these questions and meanwhile explains the early history of clinical application of photosensitizing drugs in PWS PDT in China.</div></div>","PeriodicalId":20141,"journal":{"name":"Photodiagnosis and Photodynamic Therapy","volume":"50 ","pages":"Article 104383"},"PeriodicalIF":3.1000,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodiagnosis and Photodynamic Therapy","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1572100024004204","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
It has been known for two decades that vascular acting PDT can be used as an alternative in the treatment of portwine stain (PWS) birthmarks. The modality is only used in China at the moment and an expert consensus has been published this year. A recent review article in Lasers in Surgery and Medicine summarized the available evidence based on PubMed records of PWS treatment using pulsed dye laser (PDL) and HMME-PDT. The authors observed that HMME-PDT has emerged as the first choice for PWS treatment, particularly for young children, in many major hospitals in China. The authors also raised questions on ethics of several Chinese reports. This correspondence addresses these questions and meanwhile explains the early history of clinical application of photosensitizing drugs in PWS PDT in China.
二十年前，人们就已经知道血管作用光导疗法可作为一种替代疗法用于治疗波尔文染色胎记（PWS）。目前，这种方法仅在中国使用，而专家共识已于今年发表。最近，《激光在外科和医学中的应用》（Lasers in Surgery and Medicine）杂志发表了一篇综述文章，根据PubMed上使用脉冲染料激光（PDL）和HMME-PDT治疗PWS的记录，总结了现有的证据。作者注意到，在中国许多大医院，HMME-PDT 已成为 PWB 治疗的首选，尤其是对幼儿而言。作者还对几篇中国报告的伦理问题提出了质疑。这篇通讯回答了这些问题，同时也解释了光敏药物在中国早期应用于PWS PDT临床治疗的历史。
期刊介绍：
Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.
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