Pharmaceutical perspectives of thiazole analogues: An overview

IF 4.2 Q2 CHEMISTRY, MULTIDISCIPLINARY Results in Chemistry Pub Date : 2024-10-16 DOI:10.1016/j.rechem.2024.101820
Archana R. Patil , Basappa C. Yallur , Sampath Chinnam , Guddekoppa S. Ananthnag , C.R. Santhosh , Geetika Pant , S.G. Prasanna Kumar , Manjuanth D. Hadagali
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Abstract

Thiazole derivatives have attracted considerable attention in medicinal chemistry due to their promising biological activities. This review article provides a comprehensive overview on the pharmaceutical applications of the thiazole derivatives, exploring their structural activity relationship and medical applications. We discuss the anti-cancer, anti-inflammatory, anti- oxidant, BSA and DNA interaction properties of thiazole derivatives highlighting their role in drug development. This review will be a valuable resource in medicinal chemistry. This could lead to development of drugs containing thiazoles and improve bio-compatibility and efficiency of derivatives.

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噻唑类似物的制药前景:综述
由于噻唑衍生物具有良好的生物活性,因此在药物化学领域备受关注。这篇综述文章全面概述了噻唑衍生物的药物应用,探讨了它们的结构活性关系和医疗应用。我们讨论了噻唑衍生物的抗癌、抗炎、抗氧化、BSA 和 DNA 相互作用特性,强调了它们在药物开发中的作用。这篇综述将成为药物化学领域的宝贵资源。这将有助于开发含有噻唑的药物,提高衍生物的生物相容性和效率。
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来源期刊
Results in Chemistry
Results in Chemistry Chemistry-Chemistry (all)
CiteScore
2.70
自引率
8.70%
发文量
380
审稿时长
56 days
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