Decreased hepatic CT value on immediate postmortem CT after CPR: Comparison with antemortem CT and correlation with liver enzymes changes

IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Forensic Imaging Pub Date : 2024-10-22 DOI:10.1016/j.fri.2024.200609
Tomoaki Hagita , Seiji Shiotani , Kento Inoue , Yukio Kosako , Yasuji Matsuno
{"title":"Decreased hepatic CT value on immediate postmortem CT after CPR: Comparison with antemortem CT and correlation with liver enzymes changes","authors":"Tomoaki Hagita ,&nbsp;Seiji Shiotani ,&nbsp;Kento Inoue ,&nbsp;Yukio Kosako ,&nbsp;Yasuji Matsuno","doi":"10.1016/j.fri.2024.200609","DOIUrl":null,"url":null,"abstract":"<div><div>Purpose We compared hepatic antemortem CT (AMCT) and postmortem CT (PMCT) values obtained in the same subjects. The correlations between the changes in hepatic CT values and changes in aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) values were also investigated.</div><div>Materials and methods Fifty subjects (20 males, 30 females; mean age: 85.9 ± 7.9 years; range: 67–100 years) who were transported to the emergency room in cardiopulmonary arrest (CPA) and underwent PMCT immediately after unsuccessful cardiopulmonary resuscitation (CPR) comprised the study population. The hepatic AMCT and PMCT values were both measured, and the differences between the two were calculated. The differences between AST, ALT, and LDH values at CPR and antemortem were also calculated. The correlations between the hepatic CT value differences and AST, ALT, and LDH value differences also were assessed.</div><div>Results The hepatic AMCT and PMCT values of 61.7 ± 6.8 Hounsfield Unit (HU) and 46.2 ± 8.2 HU, respectively, were significantly different. The AST, ALT, and LDH values were significantly higher at CPR than at antemortem. The differences in the hepatic CT values and in the AST, ALT, and LDH values were moderately correlated.</div><div>Conclusion The hepatic values were significantly lower on PMCT than on AMCT. The changes in hepatic CT values correlated with the changes in the liver deviation enzyme values. These results indicate the possibility that ischemic, hypoxic injury, and anerobic glycolysis of the liver at CPR after CPA are the cause of decreased hepatic PMCT values.</div></div>","PeriodicalId":40763,"journal":{"name":"Forensic Imaging","volume":"39 ","pages":"Article 200609"},"PeriodicalIF":0.8000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic Imaging","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666225624000320","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose We compared hepatic antemortem CT (AMCT) and postmortem CT (PMCT) values obtained in the same subjects. The correlations between the changes in hepatic CT values and changes in aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) values were also investigated.
Materials and methods Fifty subjects (20 males, 30 females; mean age: 85.9 ± 7.9 years; range: 67–100 years) who were transported to the emergency room in cardiopulmonary arrest (CPA) and underwent PMCT immediately after unsuccessful cardiopulmonary resuscitation (CPR) comprised the study population. The hepatic AMCT and PMCT values were both measured, and the differences between the two were calculated. The differences between AST, ALT, and LDH values at CPR and antemortem were also calculated. The correlations between the hepatic CT value differences and AST, ALT, and LDH value differences also were assessed.
Results The hepatic AMCT and PMCT values of 61.7 ± 6.8 Hounsfield Unit (HU) and 46.2 ± 8.2 HU, respectively, were significantly different. The AST, ALT, and LDH values were significantly higher at CPR than at antemortem. The differences in the hepatic CT values and in the AST, ALT, and LDH values were moderately correlated.
Conclusion The hepatic values were significantly lower on PMCT than on AMCT. The changes in hepatic CT values correlated with the changes in the liver deviation enzyme values. These results indicate the possibility that ischemic, hypoxic injury, and anerobic glycolysis of the liver at CPR after CPA are the cause of decreased hepatic PMCT values.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
心肺复苏术后立即尸检的肝脏 CT 值下降:与死前CT的比较以及与肝酶变化的相关性
目的 我们比较了同一受试者的肝脏死前 CT(AMCT)和死后 CT(PMCT)值。材料和方法 50 名受试者(男性 20 人,女性 30 人;平均年龄:85.心肺复苏(CPR)失败后立即接受 PMCT。研究人员同时测量了肝脏 AMCT 和 PMCT 值,并计算了两者之间的差异。还计算了心肺复苏时和死前的 AST、ALT 和 LDH 值之间的差异。结果 肝脏 AMCT 值为 61.7 ± 6.8 Hounsfield Unit (HU),PMCT 值为 46.2 ± 8.2 HU,两者差异显著。心肺复苏时的 AST、ALT 和 LDH 值明显高于死前。结论 PMCT 的肝功能值明显低于 AMCT。肝 CT 值的变化与肝偏差酶值的变化相关。这些结果表明,CPA 后心肺复苏时肝脏缺血、缺氧损伤和无氧糖酵解可能是导致肝脏 PMCT 值下降的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Forensic Imaging
Forensic Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.20
自引率
27.30%
发文量
39
期刊最新文献
Closed iris, long exposure photography improves three-dimensional photogrammetric bone reconstructions Cranial surgical approaches in the 21st Century Identified Skeletal Collection Unveiling the diagnostic accuracy of PMCT: Detection of pneumonia considering postmortem changes and time intervals Exploring lightweight convolution neural networks for segmenting striation marks from firearm bullet images Age estimation based on sternebral fusion in a sample of Egyptian population using three-dimensional computed tomography scanning
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1