Thermal modeling and its role in management of bifurcation aneurysms and associated ischemic complications in the middle cerebral artery

Abstract

Bifurcated aneurysm of cerebral artery is a common cerebrovascular disease, which can easily lead to serious ischemic complications. Traditional treatments face challenges of risk and effectiveness. Therefore, it is particularly important to explore new therapeutic strategies. In recent years, the application of thermal modeling techniques in medical biological systems has provided a new perspective for the analysis of hemodynamics and tissue thermal response. The purpose of this study was to investigate the role of heat model in the treatment of bifurcated cerebral artery aneurysms and their associated ischemic complications, and to evaluate its potential value in understanding disease mechanisms and optimizing treatment protocols. In this study, a three-dimensional thermal model was used to simulate the heat conduction and blood flow characteristics of the bifurcated parts of cerebral arteries. Combined with the clinical data of patients, the influence of the thermal model on the formation mechanism of aneurysms and the prognosis evaluation of ischemic complications were analyzed through numerical calculation and experimental verification. Compare the performance of different treatment methods in thermal models. The thermal model shows that the temperature distribution at the aneurysm site is closely related to the blood flow velocity, and the local temperature increase may promote thrombosis and lead to ischemic complications. The treatment regimen optimized by the thermal model showed significant improvement in the simulation, reducing the risk of complications and improving hemodynamic parameters. Heat model can reveal the dynamic relationship between blood flow and temperature in the study of cerebral artery bifurcation aneurysm, and provide theoretical support for clinical treatment.