Identification of dimethachlon metabolites and dissipation behavior, processing factor and risk assessment of dimethachlon in rapeseed

IF 5.3 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Arabian Journal of Chemistry Pub Date : 2024-10-22 DOI:10.1016/j.arabjc.2024.106030
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Abstract

Pesticides and their transformation products are found in raw agricultural and processed food products, posing risks to human health. Therefore, a thorough investigation of dimethachlon’s dissipation, metabolites, residue levels in crops, and changes during food processing is essential for an accurate dietary risk assessment. This study identified two metabolites, 4-(3,5-dichloroanilino)-4- oxobutanoic acid (DCBAA) and 3,5-dichloroaniline (3,5-DCA), formed from dimethachlon in crops under field conditions. A precise and sensitive analytical method was developed to detect dimethachlon, DCBAA, and 3,5-DCA in rapeseed pods, seeds, and oil. The half-lives of dimethachlon in rapeseed pods at two sites ranged from 1.61 to 1.67 days. During degradation, the maximum residue levels of DCBAA and 3,5-DCA in rapeseed pods reached 38.59 % and 3.47 % of the initial parent compound concentration, respectively. At harvest (day 10), final dimethachlon residues in rapeseed were 0.11 mg/kg and 0.27 mg/kg. Processing rapeseed into oil through sun-drying and stir-frying reduced dimethachlon residues, with processing factors (PF) of 0.69 and 0.64, respectively. However, pressing the seeds concentrated dimethachlon in the oil, with a PF of 1.92. Notably, DCBAA tended to concentrate during sun-drying but decreased during stir-frying and pressing. Supervised trials indicated that dimethachlon residues in rapeseed posed no long-term dietary risks.

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鉴定油菜籽中的二甲克隆代谢物和消散行为、加工因素以及二甲克隆风险评估
农药及其转化产物存在于未加工的农产品和加工食品中,对人类健康构成风险。因此,彻底调查二甲戊灵的消散、代谢物、农作物中的残留量以及食品加工过程中的变化,对于准确评估膳食风险至关重要。本研究确定了在田间条件下,农作物中的二甲草胺形成的两种代谢物,即 4-(3,5-二氯苯胺基)-4-氧代丁酸(DCBAA)和 3,5-二氯苯胺(3,5-DCA)。研究人员开发了一种精确灵敏的分析方法,用于检测油菜籽荚果、种子和油中的二甲亚龙、DCBAA 和 3,5-DCA 的含量。在两个地点的油菜籽荚中,二甲亚龙的半衰期从 1.61 天到 1.67 天不等。在降解过程中,油菜籽荚中 DCBAA 和 3,5-DCA 的最大残留量分别达到初始母体化合物浓度的 38.59% 和 3.47%。收获时(第 10 天),油菜籽中二甲亚龙的最终残留量分别为 0.11 毫克/千克和 0.27 毫克/千克。通过晒干和炒干将油菜籽加工成油可减少二甲亚龙的残留量,加工系数(PF)分别为 0.69 和 0.64。然而,压榨油菜籽会使油中的二甲亚龙含量增加,加工系数为 1.92。值得注意的是,DCBAA 在晒干过程中有浓缩的趋势,但在翻炒和压榨过程中会减少。监督试验表明,油菜籽中的二甲亚龙残留物不会造成长期的膳食风险。
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来源期刊
Arabian Journal of Chemistry
Arabian Journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
10.80
自引率
3.30%
发文量
763
审稿时长
63 days
期刊介绍: The Arabian Journal of Chemistry is an English language, peer-reviewed scholarly publication in the area of chemistry. The Arabian Journal of Chemistry publishes original papers, reviews and short reports on, but not limited to: inorganic, physical, organic, analytical and biochemistry. The Arabian Journal of Chemistry is issued by the Arab Union of Chemists and is published by King Saud University together with the Saudi Chemical Society in collaboration with Elsevier and is edited by an international group of eminent researchers.
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