Laser-induced breakdown spectroscopy (LIBS) in biomedical analysis

IF 11.8 1区 化学 Q1 CHEMISTRY, ANALYTICAL Trends in Analytical Chemistry Pub Date : 2024-10-19 DOI:10.1016/j.trac.2024.117992
{"title":"Laser-induced breakdown spectroscopy (LIBS) in biomedical analysis","authors":"","doi":"10.1016/j.trac.2024.117992","DOIUrl":null,"url":null,"abstract":"<div><div>The subtle changes in elements within a biological system can directly impact metabolism and physiological processes. Rapid and accurate analysis of elements in the body is essential for clinical disease diagnosis. Laser-induced breakdown spectroscopy (LIBS) has been widely used because it is rapid, in-situ, and micro-damage. This review summarizes the research status of LIBS in biomedical analysis in 2017–2024. The basic research of LIBS is introduced initially. Based on the different research subjects, biomedical applications of LIBS are divided into three categories, namely, microorganisms, biological tissues, and medicinal plants. LIBS plays a crucial role in enhancing the accuracy of pathogen identification in microorganisms. In biological tissues, it reveals elemental compositions that are vital for physiological analysis and pathological diagnosis. For medicinal plants, it focuses on the detection of heavy metals and adulteration to ensure safety and authenticity of medicines. Finally, the future prospects of LIBS in biomedicine are discussed.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8000,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993624004758","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0

Abstract

The subtle changes in elements within a biological system can directly impact metabolism and physiological processes. Rapid and accurate analysis of elements in the body is essential for clinical disease diagnosis. Laser-induced breakdown spectroscopy (LIBS) has been widely used because it is rapid, in-situ, and micro-damage. This review summarizes the research status of LIBS in biomedical analysis in 2017–2024. The basic research of LIBS is introduced initially. Based on the different research subjects, biomedical applications of LIBS are divided into three categories, namely, microorganisms, biological tissues, and medicinal plants. LIBS plays a crucial role in enhancing the accuracy of pathogen identification in microorganisms. In biological tissues, it reveals elemental compositions that are vital for physiological analysis and pathological diagnosis. For medicinal plants, it focuses on the detection of heavy metals and adulteration to ensure safety and authenticity of medicines. Finally, the future prospects of LIBS in biomedicine are discussed.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
激光诱导击穿光谱(LIBS)在生物医学分析中的应用
生物系统中元素的微妙变化会直接影响新陈代谢和生理过程。快速准确地分析体内元素对临床疾病诊断至关重要。激光诱导击穿光谱(LIBS)因其快速、原位、微损伤等特点而得到广泛应用。本综述总结了2017-2024年LIBS在生物医学分析中的研究现状。首先介绍了LIBS的基础研究。根据研究对象的不同,将LIBS的生物医学应用分为微生物、生物组织和药用植物三大类。LIBS 在提高微生物病原体鉴定的准确性方面发挥着重要作用。在生物组织中,它可以揭示对生理分析和病理诊断至关重要的元素组成。对于药用植物,它侧重于检测重金属和掺假,以确保药品的安全性和真实性。最后,讨论了 LIBS 在生物医学领域的未来前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Trends in Analytical Chemistry
Trends in Analytical Chemistry 化学-分析化学
CiteScore
20.00
自引率
4.60%
发文量
257
审稿时长
3.4 months
期刊介绍: TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.
期刊最新文献
Editorial Board Corrigendum to “Fluorescence detection setups in capillary electrophoresis and microscale liquid chromatography: Developments over the past decade” [Trends Anal. Chem. 181 (2024) 118001] New revolution for quality control of TCM in industry 4.0: Focus on artificial intelligence and bioinformatics Laser-induced breakdown spectroscopy (LIBS) in biomedical analysis Advances in nanomaterials based electrochemical sensors for rapid detection of food additives: A comprehensive review
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1