Adeno-squamous carcinoma of bartholin gland: Challenges in diagnosis and management of a less known vulvar cancer – A case report

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Abstract

Bartholin gland carcinoma is one of the less common histology accounting for 0.1 – 5 % of all vulvar malignancies and is mostly seen in postmenopausal women. It accounts for 0.001 % of all female malignancies. Clinical presentation is delayed to its deep-seated position in vulva. It has a propensity for frequent recurrences and distant metastases. Owing to the disease rarity, there are no well-defined management guidelines. We describe here the challenges in diagnosis and management of a case of adeno-squamous carcinoma of bartholin gland in a postmenopausal woman. Unlike the usual presentation, our case presented in an early stage with symptom of itching per vaginum. Radical surgery was the primary treatment modality with no requirement for adjuvant treatment and the patient is disease free at two years post treatment. However, adeno-squamous carcinoma of vulva has a propensity for perineural invasion and early nodal metastases and a dismal five-year survival.
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巴氏腺鳞癌:鲜为人知的外阴癌的诊断和治疗难题 - 病例报告
巴氏腺癌是一种不太常见的组织学类型,占所有外阴恶性肿瘤的 0.1 - 5%,多见于绝经后妇女。它占所有女性恶性肿瘤的 0.001%。临床表现因其位于外阴深部而延迟。它有频繁复发和远处转移的倾向。由于该病罕见,目前尚无明确的治疗指南。我们在此描述一例绝经后妇女的巴氏腺鳞癌诊断和治疗过程中遇到的挑战。与通常的病例不同,我们的病例早期即出现阴道瘙痒症状。根治性手术是主要的治疗方式,不需要辅助治疗,患者在治疗后两年无病。然而,外阴腺鳞癌容易发生会阴周围浸润和早期结节转移,五年生存率很低。
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审稿时长
96 days
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