Distinct trajectories of psychotic-like experiences and their associations with violent behavior among 3539 young adults: A 3-year prospective cohort study

IF 3.6 2区 医学 Q1 PSYCHIATRY Schizophrenia Research Pub Date : 2024-10-28 DOI:10.1016/j.schres.2024.10.012
Shaoling Zhong, Hongling Zhou, Xin Yu, Yue Li, Xinhu Yang, Jiawen Zhang, Liang Zhou, Meng Sun
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Abstract

Background

Violence perpetration may be linked to psychotic-like experiences (PLEs), but relevant research is limited, especially in general population. Therefore, we aimed to identify trajectories of PLEs and examine whether specific trajectories were related to violent behavior in a 3-year cohort study.

Methods

We developed a prospective cohort study and collected data in 2020 (T0), 2021 (T1), and 2022 (T2) in Guangzhou, China. A total of 3539 university students from two universities were included and completed self-report questionnaires to assess PLEs, violent ideation, violent threats, and violent acts. Socio-demographic and clinical factors were assessed and considered as confounding factors. We used growth mixture modeling to identify trajectories of PLEs. Associations between PLEs trajectories and violent behavior were examined using binary logistic regression.

Results

At T2, 162 (5.3 %) participants had violent behavior. We identified three distinct trajectories: low stable trajectory, low increasing trajectory, and high decreasing trajectory. The binary logistic regression models revealed that the high decreasing (OR: 2.46, 95%CI:1.60–3.72) group and the low increasing (OR: 11.7, 95%CI: 7.62–17.9) were associated with higher violent risk compared to the low stable group after controlling for baseline socio-demographic and clinical factors.

Conclusion

Our study delineated three distinct trajectories and indicated that PLEs trajectories are related to subsequent violent ideation and violent acts. The results provide crucial clarifications regarding the nature of the associations between PLEs trajectories and violence over time.
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3539 名青少年中类似精神病经历的不同轨迹及其与暴力行为的关联:为期 3 年的前瞻性队列研究
背景暴力行为可能与精神病样经历(PLEs)有关,但相关研究有限,尤其是在普通人群中。因此,我们旨在通过一项为期 3 年的队列研究,识别类精神病体验的轨迹,并考察特定轨迹是否与暴力行为有关。方法我们开展了一项前瞻性队列研究,并在中国广州收集了 2020 年(T0)、2021 年(T1)和 2022 年(T2)的数据。研究共纳入了两所大学的 3539 名大学生,他们填写了自我报告问卷,以评估 PLEs、暴力意念、暴力威胁和暴力行为。我们对社会人口学和临床因素进行了评估,并将其视为混杂因素。我们使用生长混合模型来确定 PLEs 的轨迹。结果在第二阶段,162 名参与者(5.3%)有暴力行为。我们发现了三种不同的轨迹:低稳定轨迹、低增长轨迹和高下降轨迹。二元逻辑回归模型显示,在控制了基线社会人口学和临床因素后,高递减组(OR:2.46,95%CI:1.60-3.72)和低递增组(OR:11.7,95%CI:7.62-17.9)与低稳定组相比具有更高的暴力风险。这些结果为阐明 PLEs 轨迹与暴力行为之间随时间变化的关联性质提供了重要依据。
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来源期刊
Schizophrenia Research
Schizophrenia Research 医学-精神病学
CiteScore
7.50
自引率
8.90%
发文量
429
审稿时长
10.2 weeks
期刊介绍: As official journal of the Schizophrenia International Research Society (SIRS) Schizophrenia Research is THE journal of choice for international researchers and clinicians to share their work with the global schizophrenia research community. More than 6000 institutes have online or print (or both) access to this journal - the largest specialist journal in the field, with the largest readership! Schizophrenia Research''s time to first decision is as fast as 6 weeks and its publishing speed is as fast as 4 weeks until online publication (corrected proof/Article in Press) after acceptance and 14 weeks from acceptance until publication in a printed issue. The journal publishes novel papers that really contribute to understanding the biology and treatment of schizophrenic disorders; Schizophrenia Research brings together biological, clinical and psychological research in order to stimulate the synthesis of findings from all disciplines involved in improving patient outcomes in schizophrenia.
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