Impact of tumor localization and choice of microvascular flap on posterior airway changes following ablative surgery in primary oral squamous cell carcinoma: A monocentric cross-sectional study

IF 4 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Oral oncology Pub Date : 2024-10-26 DOI:10.1016/j.oraloncology.2024.107080

Lucas M. Ritschl , Valeriya Sackerer , Katharina Pippich , Jakob K. Zink , Hannes Singer , Alex Grabenhorst , Dennis M. Hedderich , Markus H. Wirth , Klaus-Dietrich Wolff , Andreas M. Fichter , Alexandra V. Behr

{"title":"Impact of tumor localization and choice of microvascular flap on posterior airway changes following ablative surgery in primary oral squamous cell carcinoma: A monocentric cross-sectional study","authors":"Lucas M. Ritschl , Valeriya Sackerer , Katharina Pippich , Jakob K. Zink , Hannes Singer , Alex Grabenhorst , Dennis M. Hedderich , Markus H. Wirth , Klaus-Dietrich Wolff , Andreas M. Fichter , Alexandra V. Behr","doi":"10.1016/j.oraloncology.2024.107080","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The aim of this study was to determine the influence of intraoral reconstructions following oral squamous cell carcinoma (OSCC) resection with a free microvascular flap on the posterior airway space (PAS) and to correlate these results with the potential risk of developing an obstructive sleep apnea syndrome (OSAS).</div></div><div><h3>Materials and methods</h3><div>Only primary OSCC cases of the tongue or floor of the mouth which were operated and reconstructed. The PAS displayed in computed tomography (CT) scans at three time points were analyzed: t<sub>0</sub> = preoperative, t<sub>1</sub> = first postoperative CT, and t<sub>2</sub> = most recent situation. The following three PAS parameters were calculated: minimum cross-sectional area (minCSA), mean cross-sectional area (meanCSA), and volume.</div></div><div><h3>Results</h3><div>MinCSA increased from t<sub>0</sub> to t<sub>2</sub>: t<sub>0</sub> = 86.9 cm<sup>2</sup> (0.0 – 251.8), t<sub>1</sub> = 106.6 cm<sup>2</sup> (1.0 – 483.4), and t<sub>2</sub> = 124.8 cm<sup>2</sup> (0.5 – 395.6). MeanCSA increased from t<sub>0</sub> to t<sub>2</sub>: t<sub>0</sub> = 225.1 cm<sup>2</sup> (79.0 – 500.2), t<sub>1</sub> = 247.8 cm<sup>2</sup> (102.8 – 674.3), and t<sub>2</sub> = 272.2 cm<sup>2</sup> (92.2 – 668.4). The volume increased from t<sub>0</sub> to t<sub>2</sub>: t<sub>0</sub> = 21.5 cm<sup>3</sup> (8.0 – 63.2), t<sub>1</sub> = 24.1 cm<sup>3</sup> (9.6 – 67.3), and t<sub>2</sub> = 26.9 cm<sup>3</sup> (6.2 – 67.4).</div></div><div><h3>Conclusions</h3><div>Posterior airway space PAS values became higher than preoperatively. In particular, flap type had a significant influence on the three PAS parameters.</div></div>","PeriodicalId":19716,"journal":{"name":"Oral oncology","volume":"159 ","pages":"Article 107080"},"PeriodicalIF":4.0000,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral oncology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1368837524003981","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Background

The aim of this study was to determine the influence of intraoral reconstructions following oral squamous cell carcinoma (OSCC) resection with a free microvascular flap on the posterior airway space (PAS) and to correlate these results with the potential risk of developing an obstructive sleep apnea syndrome (OSAS).

Materials and methods

Only primary OSCC cases of the tongue or floor of the mouth which were operated and reconstructed. The PAS displayed in computed tomography (CT) scans at three time points were analyzed: t₀ = preoperative, t₁ = first postoperative CT, and t₂ = most recent situation. The following three PAS parameters were calculated: minimum cross-sectional area (minCSA), mean cross-sectional area (meanCSA), and volume.

Results

MinCSA increased from t₀ to t₂: t₀ = 86.9 cm² (0.0 – 251.8), t₁ = 106.6 cm² (1.0 – 483.4), and t₂ = 124.8 cm² (0.5 – 395.6). MeanCSA increased from t₀ to t₂: t₀ = 225.1 cm² (79.0 – 500.2), t₁ = 247.8 cm² (102.8 – 674.3), and t₂ = 272.2 cm² (92.2 – 668.4). The volume increased from t₀ to t₂: t₀ = 21.5 cm³ (8.0 – 63.2), t₁ = 24.1 cm³ (9.6 – 67.3), and t₂ = 26.9 cm³ (6.2 – 67.4).

Conclusions

Posterior airway space PAS values became higher than preoperatively. In particular, flap type had a significant influence on the three PAS parameters.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

原发性口腔鳞状细胞癌消融手术后肿瘤定位和微血管瓣选择对后气道变化的影响：单中心横断面研究

背景本研究旨在确定口腔鳞状细胞癌（OSCC）切除术后使用游离微血管瓣进行口内重建对后气道间隙（PAS）的影响，并将这些结果与患阻塞性睡眠呼吸暂停综合征（OSAS）的潜在风险联系起来。分析了三个时间点的计算机断层扫描（CT）显示的 PAS：t0 = 术前，t1 = 术后第一次 CT，t2 = 最近一次。结果最小横截面积从 t0 增加到 t2：t0 = 86.9 平方厘米（0.0 - 251.8），t1 = 106.6 平方厘米（1.0 - 483.4），t2 = 124.8 平方厘米（0.5 - 395.6）。平均 CSA 从 t0 增加到 t2：t0 = 225.1 平方厘米（79.0 - 500.2），t1 = 247.8 平方厘米（102.8 - 674.3），t2 = 272.2 平方厘米（92.2 - 668.4）。体积从 t0 增加到 t2：t0 = 21.5 cm3（8.0 - 63.2），t1 = 24.1 cm3（9.6 - 67.3），t2 = 26.9 cm3（6.2 - 67.4）。特别是，皮瓣类型对三个 PAS 参数有显著影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Oral oncology 医学-牙科与口腔外科

CiteScore

8.70

自引率

10.40%

发文量

505

审稿时长

20 days

期刊介绍： Oral Oncology is an international interdisciplinary journal which publishes high quality original research, clinical trials and review articles, editorials, and commentaries relating to the etiopathogenesis, epidemiology, prevention, clinical features, diagnosis, treatment and management of patients with neoplasms in the head and neck. Oral Oncology is of interest to head and neck surgeons, radiation and medical oncologists, maxillo-facial surgeons, oto-rhino-laryngologists, plastic surgeons, pathologists, scientists, oral medical specialists, special care dentists, dental care professionals, general dental practitioners, public health physicians, palliative care physicians, nurses, radiologists, radiographers, dieticians, occupational therapists, speech and language therapists, nutritionists, clinical and health psychologists and counselors, professionals in end of life care, as well as others interested in these fields.