Recent Advances in Amperometric Biosensors for Medical Applications: A Mini-Review.

IF 2.9 4区 医学 Q3 CHEMISTRY, MEDICINAL Current topics in medicinal chemistry Pub Date : 2024-10-28 DOI:10.2174/0115680266323004241015122441
Anna S Kharkova, Lubov S Kuznetsova, Kristina D Ivanova, Maria M Gertsen, Vyacheslav A Arlyapov
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Abstract

Amperometric biosensors have emerged as a cutting-edge technology in clinical diagnostics, thanks to their high level of sensitivity, rapid analytical results, compact size, and ability to monitor health parameters non-invasively and continuously using flexible and wearable sensors. This review explores the latest developments in the field of amperometric biosensing for medical applications. It discusses the materials used to construct these sensors and pays particular attention to biosensors designed to measure glucose, lactate, cholesterol, urea, and uric acid levels. The review also addresses the technological limitations and drawbacks of these devices. Furthermore, it presents the current status and identifies future trends in the development of flexible, wearable biosensors capable of providing continuous monitoring of a patient's health status.

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用于医疗应用的安培生物传感器的最新进展:微型综述。
安培计生物传感器灵敏度高、分析速度快、体积小巧,并能利用灵活的可穿戴传感器对健康参数进行无创和连续监测,因此已成为临床诊断领域的尖端技术。本综述探讨了用于医疗应用的安培计生物传感领域的最新发展。它讨论了用于构建这些传感器的材料,并特别关注设计用于测量葡萄糖、乳酸盐、胆固醇、尿素和尿酸水平的生物传感器。该综述还讨论了这些设备的技术限制和缺点。此外,它还介绍了能够持续监测病人健康状况的柔性可穿戴生物传感器的发展现状,并指出了未来的发展趋势。
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来源期刊
CiteScore
6.40
自引率
2.90%
发文量
186
审稿时长
3-8 weeks
期刊介绍: Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.
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