Qijia Sun , Aoqing Jia , Min Zhao , Ke Wang , Tingting Sun , Zhigang Xie
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引用次数: 0
Abstract
Phototherapeutic antimicrobials, including photodynamic and photothermal antimicrobials, are considered effective alternatives for antibiotic strategy due to their broad-spectrum antibacterial activity and low risk of resistance. Here, a 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) derivative containing triphenylamine groups was co-assembled with Pluronic F-127 (F-127) to form nanoparticles (BICF NPs). BICF NPs have excellent photodynamic and photothermal properties and are demonstrated to be effective in inhibiting and disrupting bacterial biofilms, thereby promoting the healing of subcutaneous abscesses. This work provides a new avenue for antibiotic replacement therapy.
期刊介绍：
The Journal of Photochemistry and Photobiology B: Biology provides a forum for the publication of papers relating to the various aspects of photobiology, as well as a means for communication in this multidisciplinary field.
The scope includes:
- Bioluminescence
- Chronobiology
- DNA repair
- Environmental photobiology
- Nanotechnology in photobiology
- Photocarcinogenesis
- Photochemistry of biomolecules
- Photodynamic therapy
- Photomedicine
- Photomorphogenesis
- Photomovement
- Photoreception
- Photosensitization
- Photosynthesis
- Phototechnology
- Spectroscopy of biological systems
- UV and visible radiation effects and vision.
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