Perceived Cognitive Function in Neurosurgical Patients.

IF 3.9 2区 医学 Q1 CLINICAL NEUROLOGY Neurosurgery Pub Date : 2024-10-08 DOI:10.1227/neu.0000000000003207
Natalie Sherry, Shawn R Eagle, Luke C Henry, Hannah Appleton, Jorge A González Martínez, Robert M Friedlander, David O Okonkwo, Pascal O Zinn
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Abstract

Background and objectives: This study explores perceived cognitive function in preoperative cranial neurosurgical patients and its association with neuropsychological testing (NPT).

Methods: A total of 96 patients were referred for NPT by neurosurgical service. Patients completed the Neuro-QoL Item Bank v2.0-Cognitive Function-Short Form (Neuro-QoL) to measure perceived cognitive function, as well as NPT. Linear regression (LR) models were analyzed for demographic variables (ie, age, sex, handedness, educational attainment, employment/academic status, candidacy vs baseline testing, and history of neurological, mental health, and developmental conditions) and NPT outcomes (ie, intellectual estimation, attention/working memory, processing speed, executive functioning, learning/memory, language, visual-spatial, anxiety symptoms, and depression symptoms). Significant predictors from the LR models were then combined into a single model to identify the most robust predictors of perceived cognitive function.

Results: Patients were aged 17 to 79 years (M = 49.64, SD = 18.56) and comprised 45 men and 51 women. The most common referrals for NPT were related to intracranial mass (39%), Chiari malformation type 1 (33%), and deep brain stimulation (20%). Results of the final LR model indicated mental health and developmental history, as well as elevated anxiety symptoms, significantly predicted 50.7% of the variance in perceived cognitive function (F = 30.91, P < .001). Patients referred to determine surgical candidacy reported significantly fewer cognitive complaints (P < .001) vs those referred for baseline testing by approximately 0.5 SDs.

Conclusion: Perceived cognitive function in neurosurgical patients appears to be strongly predicted by demographic factors, with mental health variables being robust predictors. Perceived cognition is not a proxy for measured cognitive function.

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神经外科患者的认知功能感知。
背景和目的:本研究探讨了颅脑神经外科患者术前的认知功能及其与神经心理测试(NPT)的关系:方法:共有 96 名患者由神经外科转介接受神经心理测试。患者填写了神经-QoL项目库v2.0-认知功能简表(Neuro-QoL),以测量认知功能感知和NPT。线性回归(LR)模型分析了人口统计学变量(即年龄、性别、手型、教育程度、就业/学业状况、候选资格与基线测试,以及神经、心理健康和发育状况病史)和 NPT 结果(即智力估计、注意力/工作记忆、处理速度、执行功能、学习/记忆、语言、视觉空间、焦虑症状和抑郁症状)。然后将LR模型中的重要预测因子合并到一个单一模型中,以确定认知功能感知的最可靠预测因子:患者年龄在 17 至 79 岁之间(中位数 = 49.64,标准差 = 18.56),其中男性 45 人,女性 51 人。最常见的 NPT 转诊病例与颅内肿块(39%)、Chiari 畸形 1 型(33%)和深部脑刺激(20%)有关。最终 LR 模型的结果表明,心理健康和发育史以及焦虑症状的升高可显著预测认知功能感知方差的 50.7%(F = 30.91,P < .001)。为确定手术候选资格而转诊的患者报告的认知症状明显少于为基线测试而转诊的患者(P < .001),相差约 0.5 SDs:结论:神经外科患者的认知功能似乎受到人口统计学因素的强烈影响,而心理健康变量是强有力的预测因素。感知认知并不能代表测量的认知功能。
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来源期刊
Neurosurgery
Neurosurgery 医学-临床神经学
CiteScore
8.20
自引率
6.20%
发文量
898
审稿时长
2-4 weeks
期刊介绍: Neurosurgery, the official journal of the Congress of Neurological Surgeons, publishes research on clinical and experimental neurosurgery covering the very latest developments in science, technology, and medicine. For professionals aware of the rapid pace of developments in the field, this journal is nothing short of indispensable as the most complete window on the contemporary field of neurosurgery. Neurosurgery is the fastest-growing journal in the field, with a worldwide reputation for reliable coverage delivered with a fresh and dynamic outlook.
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