Comment on: Fetal femur length and risk of diabetes in adolescence: a prospective cohort study.

Abstract

We read the article "Fetal Femur Length and Risk of Diabetes in Adolescence: A Prospective Cohort Study" by Sayeed et al. with great interest. The authors present compelling evidence linking mid-trimester impaired femur growth with elevated prediabetic biomarkers in Bangladeshi adolescents. However, we believe the study would benefit from considering additional factors. Maternal gestational diabetes, a well-known risk factor for type 2 diabetes mellitus (T2DM) in offspring, and family history of diabetes, which reflects genetic predisposition, should be included. Socioeconomic factors, which influence health outcomes, also warrant attention. Including these variables would provide a more comprehensive understanding of the relationship between fetal femur length and T2DM risk in adolescents.