Impacts of the COVID-19 pandemic on the availability and retail price of unregulated drugs in Vancouver, Canada: An interrupted time-series analysis, 2018-2022

IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE International Journal of Drug Policy Pub Date : 2024-10-30 DOI:10.1016/j.drugpo.2024.104633
Anmol Swaich , Delaney Ignatieff , M-J Milloy , JinCheol Choi , Thomas Kerr , Kanna Hayashi
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Abstract

Background

Impacts of the COVID-19 pandemic on unregulated drug markets in North America have not been well characterized. We sought to estimate potential changes in the availability and retail price of unregulated drugs in Vancouver, Canada pre- vs. post-emergence of the COVID-19 pandemic.

Methods

We used self-report data from two prospective cohorts of people who use drugs in Vancouver. We employed interrupted time series analyses to identify changes in the monthly prevalence of immediate availability (i.e., within 10 minutes vs. any longer) and median retail price of crystal methamphetamine, powder cocaine, crack cocaine, and ‘down’ (the local term for unregulated opioids, e.g., heroin, fentanyl, etc), post-pandemic emergence (i.e. post-July 2020).

Results

Between 2018 and 2022 among 739 participants, the monthly prevalence of immediate availability significantly decreased for all drugs immediately post- emergence of the pandemic (all p<0.05). The monthly prevalence of immediate availability of cocaine declined most (-18.1%, 95% confidence interval [CI]: -25.9, -10.4) and the immediate availability of ‘down’ declined least (-13.0%, 95% CI:-18.8, -7.3). In analyses of median price, the only significant change was in the price of cocaine, which increased by $3.46 per 0.5 grams (95% CI:1.0, 5.9) immediately post-emergence of the pandemic.

Conclusion

While more research is needed to investigate reasons for the observed trends, the stagnant price amidst decreased availability for all drugs examined in this study (save cocaine) may reflect decreased purity/increased contamination of unregulated drugs following the beginning of the pandemic in our study setting. These findings may have implications for drug policy and practice approaches, particularly in regions where synthetic psychoactive substances are increasingly dominating the unregulated drug supply.
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COVID-19 大流行对加拿大温哥华非管制药品供应和零售价格的影响:2018-2022年间断时间序列分析。
背景:COVID-19 大流行对北美非管制药品市场的影响尚未得到很好的描述。我们试图估算 COVID-19 大流行前后加拿大温哥华未管制药品的供应和零售价格的潜在变化:我们使用了温哥华两组前瞻性吸毒者的自我报告数据。我们采用了间断时间序列分析,以确定大流行出现后(即 2020 年 7 月后)冰毒、可卡因粉、快克可卡因和 "down"(当地术语,指不受管制的阿片类药物,如海洛因、芬太尼等)的每月即时供应率(即 10 分钟内与更长时间内)和零售价中位数的变化:结果:2018 年至 2022 年间,在 739 名参与者中,大流行出现后所有药物的每月即时供应流行率显著下降(所有 pConclusion):虽然还需要更多的研究来调查所观察到的趋势的原因,但本研究中调查的所有毒品(除可卡因外)在供应减少的同时价格却停滞不前,这可能反映了在我们的研究环境中,大流行开始后未受管制的毒品纯度下降/污染增加。这些发现可能会对毒品政策和实践方法产生影响,特别是在合成精神活性物质日益主导不受管制的毒品供应的地区。
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来源期刊
CiteScore
7.80
自引率
11.40%
发文量
307
审稿时长
62 days
期刊介绍: The International Journal of Drug Policy provides a forum for the dissemination of current research, reviews, debate, and critical analysis on drug use and drug policy in a global context. It seeks to publish material on the social, political, legal, and health contexts of psychoactive substance use, both licit and illicit. The journal is particularly concerned to explore the effects of drug policy and practice on drug-using behaviour and its health and social consequences. It is the policy of the journal to represent a wide range of material on drug-related matters from around the world.
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