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Outcomes and implications of British Columbia's 'drug decriminalization initiative' for health-oriented drug policymaking. 不列颠哥伦比亚省“药物非刑事化倡议”对面向健康的药物决策的结果和影响。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-06 DOI: 10.1016/j.drugpo.2026.105181
Benedikt Fischer, Didier Jutras-Aswad, Bernard Le Foll, Daniel T Myran
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引用次数: 0
The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: a multistage systematic review. 被监禁者中注射吸毒、艾滋病毒、病毒性肝炎和结核病的全球流行病学:一项多阶段系统综述。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-05 DOI: 10.1016/j.drugpo.2025.105062
Louisa Degenhardt, Matthew Hickman, Frederick L Altice, Jason Grebely, Sophia Taylor, Michelle Lynch, Aleksa Kamenjas, Jack Marsden, Lucy T Tran, Paige Webb, Olivia Price, Christel Macdonald, Filipa Alves da Costa, Justin Berk, Anja Busse, Evan Cunningham, Colleen Daniels, Behzad Hajarizadeh, Linda Montanari, Luis Royuela, Keith Sabin, Jack Stone, Annette Verster, Peter Vickerman, Michael Farrell, Thomas Santo

Background: This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people who are incarcerated.

Methods: We conducted a systematic search of peer-reviewed (Medline, Embase, PsycINFO), internet, and grey literature databases, from January 2000 through 2nd June 2025 and engaged international experts and relevant agencies liaising with key agencies focused on incarcerated populations (WHO, UNODC, UNAIDS and EUDA). Data on study methods, size of incarcerated populations and demographic characteristics, and prevalence of IDU, HIV, HCV, HBV and tuberculosis among incarcerated populations were extracted. Meta-analyses pooled data where multiple estimates were available for a country; regional and global estimates were calculated, weighted by incarcerated population size. We present overall country, regional and global prevalence estimates for each variable examined, stratified by sex. We then estimated the ratio of IDU, HIV, HCV, HBV and tuberculosis prevalence among incarcerated populations compared to the general population.

Results: Of 75,755 screened documents, 2,968 were eligible for data extraction. There are approximately 11,322,000 people aged 15-64 years incarcerated globally with their incarceration rate being 221 per 100,000 (29 per 100,000 among females and 404 per 100,000 among males). Substantial variation in rates across countries and regions were observed with the highest regional rate being in North America. Globally, we estimate that 11·9% of people who are incarcerated have ever injected drugs (1,348,000; 95%CI 1,061,500-1,687,000), 51·4 times higher than the general population. We estimate that 3·7% (95%CI 2·5-5·4) of people who are incarcerated globally are living with HIV (25.1· times higher than the general population); 11·7% (95%CI 7·7-17·1) have current HCV infection (15·6 times higher); 4·4% (95%CI 2·4-7·7) have current HBV infection (2·2 times higher) and 2·5% (95%CI 1·5-3·8) have active tuberculosis (45·3 times higher than the general population). There is substantial variation geographically and among females and males.

Conclusion: The substantial concentration of people with multiple risks and comorbidities requires improved strategies to screen, evaluate, treat and prevent these adverse consequences, which is crucial for global control efforts.

Funding: Australian National Health and Medical Research Council.

背景:本全球系统综述评估了被监禁人员中注射吸毒(IDU)和主要传染病(HIV、丙型肝炎病毒(HCV)、结核病和乙型肝炎病毒(HBV))的流行情况。方法:从2000年1月至2025年6月2日,我们对同行评审(Medline、Embase、PsycINFO)、互联网和灰色文献数据库进行了系统检索,并与关注被监禁人群的主要机构(世卫组织、毒品和犯罪问题办公室、联合国艾滋病规划署和欧洲开发署)的国际专家和相关机构进行了联络。提取了有关研究方法、监禁人口规模和人口统计学特征的数据,以及监禁人口中IDU、HIV、HCV、HBV和结核病的患病率。荟萃分析汇集了一个国家的多个估计数据;计算了区域和全球的估计,并按监禁人口规模加权。我们给出了每个检查变量的总体国家、区域和全球患病率估计,并按性别分层。然后,与一般人群相比,我们估计了被监禁人群中IDU、HIV、HCV、HBV和结核病患病率的比例。结果:在筛选的75,755份文献中,有2,968份符合数据提取条件。全球大约有11,322,000名15-64岁的人被监禁,监禁率为每100,000人中有221人(女性为每100,000人中有29人,男性为每100,000人中有404人)。不同国家和地区的发病率差异很大,北美地区的发病率最高。在全球范围内,我们估计11.9%的被监禁者曾经注射过毒品(1348,000;95%CI 1,061,500-1,687,000),比一般人群高51.4倍。我们估计,全球被监禁的人中有3.7% (95%CI 2.5 - 5.4)是艾滋病毒携带者(比一般人群高25.1倍);11.7% (95%CI 7.7 - 17.1)目前感染HCV(高出15.6倍);4.4% (95%CI 2.4 - 7.7)的人目前感染HBV(高出2.2倍),2.5% (95%CI 1.5 - 3.8)的人患有活动性结核病(高出普通人群45.3倍)。在地域和男女之间存在很大差异。结论:具有多种风险和合并症的人群大量集中,需要改进筛查、评估、治疗和预防这些不良后果的策略,这对全球控制工作至关重要。资助:澳大利亚国家卫生和医学研究委员会。
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引用次数: 0
Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review. 在监狱和其他监狱环境中减少注射吸毒相关伤害、艾滋病毒、病毒性肝炎和结核病的干预措施的全球覆盖面:系统审查。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-05 DOI: 10.1016/j.drugpo.2025.105069
Thomas Santo, Matthew Hickman, Frederick L Altice, Jason Grebely, Sophia Taylor, Michelle Lynch, Aleksa Kamenjaš, Jack Marsden, Lucy T Tran, Paige Webb, Olivia Price, Christel Macdonald, Linda Montanari, Luis Royuela, Anja Busse, Jack Stone, Filipa Alves da Costa, Justin Berk, Colleen Daniels, Evan Cunningham, Peter Vickerman, Behzad Hajarizadeh, Keith Sabin, Annette Verster, Michael Farrell, Louisa Degenhardt

Background: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of services that prevent and manage infectious disease, injecting drug use and related harms remain limited and outdated. We provide the first systematic review to comprehensively examine the availability and coverage of infectious disease prevention, treatment, and harm reduction services for incarcerated populations globally.

Methods: We conducted a systematic review of evidence for provision of opioid agonist treatment (OAT), needle syringe programs (NSPs), HIV testing and antiretroviral therapy (ART), hepatitis C virus (HCV) testing and direct-acting antiviral (DAA) treatment, tuberculosis screening and treatment, hepatitis B virus (HBV) testing, treatment, and vaccination in carceral settings. We searched from peer-reviewed and grey literature databases between 2000 and 2025 and used the most recent data available for each indicator.

Findings: OAT was documented in 59/207 countries (29 %), and NSPs in ten (5 %). HIV testing was documented in 86 countries (42 %) and ART in 79 countries (38 %). HCV testing was confirmed in 55 (27 %), with DAA treatment in 47 (23 %). HBV testing was identified in 51 countries (25 %), treatment in 36 (17 %), and vaccination in 41 (20 %). Tuberculosis screening was documented in 96 countries (46 %) and treatment in 81 (39 %). Fewer than 2 % (approximately 192,500) of the 11.3 million people incarcerated worldwide live in countries that offer OAT, NSPs, and treatment for HIV, HCV, HBV, and tuberculosis in at least one carceral facility. There is not a single country where incarcerated people have access to all such services in every facility. Programme level evidence was rarely available.

Interpretation: The global shortage of services that prevent and treat infectious disease and harms related to injecting drug use in carceral settings is a critical public health issue and, compared with community standards, a breach of human rights. This study underscores the urgent need for international collaboration and policy reform to scale up and stabilise services that address the health needs of incarcerated populations, ultimately improving health outcomes for both incarcerated populations and wider community.

Funding: Australian National Health and Medical Research Council.

背景:被监禁者注射吸毒和感染传染病(包括艾滋病毒、病毒性肝炎和结核病)的比例高得不成比例。然而,关于预防和管理传染病、注射吸毒及相关危害的服务提供情况的全面全球数据仍然有限且过时。我们提供了第一个系统综述,全面检查传染病预防、治疗和减少危害服务的可用性和覆盖范围,为全球监禁人口。方法:我们对阿片类激动剂治疗(OAT)、针头注射计划(NSPs)、艾滋病毒检测和抗逆转录病毒治疗(ART)、丙型肝炎病毒(HCV)检测和直接作用抗病毒(DAA)治疗、结核病筛查和治疗、乙型肝炎病毒(HBV)检测、治疗和在癌症环境中接种疫苗的证据进行了系统回顾。我们从2000年至2025年的同行评审和灰色文献数据库中进行了检索,并使用了每个指标的最新数据。研究结果:在59/207个国家(29%)有OAT记录,在10个国家(5%)有nsp记录。86个国家(42%)记录了艾滋病毒检测,79个国家(38%)记录了抗逆转录病毒治疗。55人(27%)接受HCV检测,47人(23%)接受DAA治疗。51个国家进行了HBV检测(25%),36个国家进行了治疗(17%),41个国家进行了疫苗接种(20%)。96个国家(46%)记录了结核病筛查,81个国家(39%)记录了结核病治疗。在全世界1130万被监禁者中,只有不到2%(约19.25万人)生活在提供OAT、NSPs以及在至少一所监狱设施中提供艾滋病毒、丙型肝炎病毒、乙型肝炎病毒和结核病治疗的国家。在任何一个国家,被监禁的人都可以在每个设施中获得所有这些服务。很少有方案层面的证据。解释:在监狱环境中预防和治疗传染病和与注射吸毒有关的危害的服务在全球范围内短缺,这是一个重大的公共卫生问题,与社区标准相比,这是对人权的侵犯。这项研究强调迫切需要进行国际合作和政策改革,以扩大和稳定解决被监禁人口健康需求的服务,最终改善被监禁人口和更广泛社区的健康结果。资助:澳大利亚国家卫生和医学研究委员会。
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引用次数: 0
Urban–rural disparities in oral nicotine pouch sales and flavors in the United States 美国口服尼古丁袋装销售和口味的城乡差异
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-03 DOI: 10.1016/j.drugpo.2026.105178
Lei Xu , Saber Feizy , Megan E Roberts , Ce Shang , Brittney Keller-Hamilton , Darren Mays , Shyanika W Rose , Yanyun He

Background

As oral nicotine pouches (ONPs) gain popularity in the United States, the extent to which product attributes, such as price and flavor, affect sales remains unclear. Examining urban–rural differences is particularly important given longstanding disparities in smokeless tobacco use and tobacco-related health outcomes across these settings, yet little is known about whether ONP sales and attribute preferences differ between urban and rural areas.

Objectives

This study aims to examine how ONP sales are associated with product attributes and sales locations (rural vs. urban), and whether the associations between sales and attributes differ by urban/rural locations.

Methods

We linked 2021 NielsenIQ retail sales data with the National Center for Health Statistics county-level urban/rural classifications. Flavors were grouped as implicit (marketed without explicit flavor names), mint/menthol, fruity, or other. Multivariable linear regression models were used by regressing ONP sales on product attributes, rural/urban status, and their interactions.

Results

In 2021, 88% of total ONP sales occurred in urban areas, compared with 12% in rural areas. ONP sales per 1000 population were 16% higher in rural than urban areas (p < 0.001). Compared to the sales of implicitly flavored ONPs, sales of mint/menthol, fruit, and other flavors were approximately 23-fold, 4-fold, and 7-fold higher, respectively. These flavor-related differences were less pronounced in rural counties than in urban counties. The price elasticity of demand was –0.66 (p < 0.001) in urban areas and –0.33 (p < 0.001) in rural areas.

Conclusions

ONP sales exhibit significant urban–rural disparities, with rural areas showing higher per capita sales overall, but urban areas showing stronger preferences for flavored products and greater price responsiveness. As a result, regulatory measures targeting flavors or pricing may have a greater impact in urban areas compared to rural ones.
随着口服尼古丁袋(ONPs)在美国越来越受欢迎,产品属性(如价格和口味)对销售的影响程度仍不清楚。鉴于无烟烟草使用和烟草相关健康结果在这些环境中的长期差异,检查城乡差异尤为重要,但人们对城乡地区的ONP销售和属性偏好是否存在差异知之甚少。本研究旨在研究ONP销售如何与产品属性和销售地点(农村与城市)相关联,以及销售和属性之间的关联是否因城市/农村地点而异。方法:我们将2021年尼尔森iq零售销售数据与国家卫生统计中心县级城市/农村分类相关联。口味分为隐性(没有明确的口味名称)、薄荷/薄荷醇、水果味或其他。采用多变量线性回归模型,将ONP销售额与产品属性、城乡状况及其相互作用进行回归。结果2021年,88%的ONP销售发生在城市地区,而农村地区为12%。农村每1000人的ONP销售额比城市地区高16% (p < 0.001)。与含蓄风味的onp相比,薄荷/薄荷醇、水果和其他口味的销售额分别高出约23倍、4倍和7倍。这些与口味相关的差异在农村县比在城市县不那么明显。城市地区需求的价格弹性为-0.66 (p < 0.001),农村地区为-0.33 (p < 0.001)。结论sonp销售表现出明显的城乡差异,农村地区的人均销售额总体较高,而城市地区对调味产品的偏好更强,价格反应能力更强。因此,针对口味或价格的监管措施在城市地区可能比在农村地区产生更大的影响。
{"title":"Urban–rural disparities in oral nicotine pouch sales and flavors in the United States","authors":"Lei Xu ,&nbsp;Saber Feizy ,&nbsp;Megan E Roberts ,&nbsp;Ce Shang ,&nbsp;Brittney Keller-Hamilton ,&nbsp;Darren Mays ,&nbsp;Shyanika W Rose ,&nbsp;Yanyun He","doi":"10.1016/j.drugpo.2026.105178","DOIUrl":"10.1016/j.drugpo.2026.105178","url":null,"abstract":"<div><h3>Background</h3><div>As oral nicotine pouches (ONPs) gain popularity in the United States, the extent to which product attributes, such as price and flavor, affect sales remains unclear. Examining urban–rural differences is particularly important given longstanding disparities in smokeless tobacco use and tobacco-related health outcomes across these settings, yet little is known about whether ONP sales and attribute preferences differ between urban and rural areas.</div></div><div><h3>Objectives</h3><div>This study aims to examine how ONP sales are associated with product attributes and sales locations (rural vs. urban), and whether the associations between sales and attributes differ by urban/rural locations.</div></div><div><h3>Methods</h3><div>We linked 2021 NielsenIQ retail sales data with the National Center for Health Statistics county-level urban/rural classifications. Flavors were grouped as implicit (marketed without explicit flavor names), mint/menthol, fruity, or other. Multivariable linear regression models were used by regressing ONP sales on product attributes, rural/urban status, and their interactions.</div></div><div><h3>Results</h3><div>In 2021, 88% of total ONP sales occurred in urban areas, compared with 12% in rural areas. ONP sales per 1000 population were 16% higher in rural than urban areas (<em>p</em> &lt; 0.001). Compared to the sales of implicitly flavored ONPs, sales of mint/menthol, fruit, and other flavors were approximately 23-fold, 4-fold, and 7-fold higher, respectively. These flavor-related differences were less pronounced in rural counties than in urban counties. The price elasticity of demand was –0.66 (<em>p</em> &lt; 0.001) in urban areas and –0.33 (<em>p</em> &lt; 0.001) in rural areas.</div></div><div><h3>Conclusions</h3><div>ONP sales exhibit significant urban–rural disparities, with rural areas showing higher per capita sales overall, but urban areas showing stronger preferences for flavored products and greater price responsiveness. As a result, regulatory measures targeting flavors or pricing may have a greater impact in urban areas compared to rural ones.</div></div>","PeriodicalId":48364,"journal":{"name":"International Journal of Drug Policy","volume":"150 ","pages":"Article 105178"},"PeriodicalIF":4.4,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146098756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The emergence of problematic cannabis use as a network phenomenon. 大麻使用问题的出现是一种网络现象。
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-02-03 DOI: 10.1016/j.drugpo.2026.105175
Ronja Maria Järvelin

This study examines the emergence of problematic cannabis use as a dynamic, networked, and affective process. Drawing on Actor-Network Theory and Deleuze's concept of affect, the analysis explores how shifting assemblages of human and non-human actors shape agency over time. The data consist of interviews with 23 participants and 16 written accounts submitted by individuals who self-identified their cannabis use as problematic. Through close reading of participants' narratives combined with network mapping, three phases were identified: opening, sustaining, and restricting networks. In the opening phase, network relations expand affective capacity by opening up new ways of thinking and extending the body's range of movement in space. In the sustaining phase, these relations stabilize as cannabis becomes part of everyday routines that reproduce familiar rhythms rather than generating new openings. In the restricting phase, configurations involving specific material fixators (such as the bed, sofa, or digital devices) begin to limit spatial, emotional, and embodied possibilities, resulting in a contraction of affective capacity. These phases offer a heuristic framework for analyzing how problematic use stabilizes within socio-material assemblages, rather than as an outcome of isolated individual vulnerabilities. This perspective contributes to ongoing discussions in drug research by emphasizing relational dynamics and may inform treatment by identifying core networked actors that sustain or limit agency. Future research should examine how restricting networks may unravel and give rise to new affective landscapes.

本研究探讨了问题大麻使用的出现作为一个动态的,网络化的,和情感的过程。利用行动者网络理论和德勒兹的情感概念,分析探讨了人类和非人类行动者的变化组合如何随着时间的推移塑造代理。这些数据包括对23名参与者的采访和16份由自我认定大麻使用有问题的个人提交的书面报告。通过仔细阅读参与者的叙述并结合网络映射,我们确定了三个阶段:开放、维持和限制网络。在开放阶段,网络关系通过开辟新的思维方式和扩大身体在空间中的活动范围来扩展情感能力。在维持阶段,这些关系稳定下来,因为大麻成为日常生活的一部分,再现了熟悉的节奏,而不是产生新的开放。在限制阶段,涉及特定物质固定物(如床、沙发或数字设备)的配置开始限制空间、情感和具体化的可能性,导致情感能力的收缩。这些阶段提供了一个启发式框架,用于分析有问题的使用如何在社会物质组合中稳定下来,而不是作为孤立的个体脆弱性的结果。这一观点通过强调关系动力学有助于药物研究中正在进行的讨论,并可能通过确定维持或限制代理的核心网络参与者来告知治疗。未来的研究应该检查限制网络如何解开并产生新的情感景观。
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引用次数: 0
Barriers to evidence-based alcohol policies in France: Insights from interviews with parliament members 法国基于证据的酒精政策的障碍:来自议会成员采访的见解
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-01-30 DOI: 10.1016/j.drugpo.2026.105172
Ana Millot , François Topart , Janet Hoek , Karine Gallopel-Morvan

Background

In France, the evidence-based policies recommended by the World Health Organization SAFER program remain poorly implemented, despite relatively high levels of alcohol consumption and alcohol-related harms. To understand this paradox, we used Kingdon’s Multiple Streams Approach (MSA) as framework to analyze how members of the French parliament perceive alcohol and how alcohol industry and public health actors influence their decision-making.

Methods

We conducted twenty-five interviews with French deputies and senators from different political parties and regions. We built the interview guide following the three MSA streams: problem, policy, and political. We performed a thematic content analysis of the interview data using Nvivo to manage the data.

Results

The interviewed deputies and senators held ambivalent views on alcohol (problem stream): they acknowledged its health and social harms, but also emphasized its cultural and economic benefits. They supported low-evidence-based alcohol policies (e.g., education and targeted prevention) and showed limited support for Minimum Unit Pricing (MUP) policies (policy stream). Several arguments used by the alcohol industry against MUP emerged, including negative economic effects and illicit trade. The interviewed deputies and senators also reported more frequent interactions with alcohol industry actors than with public health actors (political stream).

Conclusion

In line with the MSA streams, our findings suggest that ambivalent framing of alcohol, weak support for evidence-based measures and a wine-favorable political environment may explain the weak alcohol control policies in France. Future research should include additional stakeholders to capture the full set of dynamics that contribute to policy inertia.
在法国,尽管酒精消费量和酒精相关危害相对较高,但世界卫生组织SAFER计划推荐的循证政策执行不力。为了理解这一悖论,我们使用金敦的多流方法(MSA)作为框架来分析法国议会成员如何看待酒精以及酒精行业和公共卫生行为者如何影响他们的决策。方法对来自不同政党和地区的法国众议员和参议员进行了25次访谈。我们根据三个MSA流构建了采访指南:问题、政策和政治。我们使用Nvivo对访谈数据进行了主题内容分析。结果受访的众议员和参议员对酒精(问题流)持有矛盾的看法:他们承认酒精对健康和社会的危害,但也强调它的文化和经济效益。他们支持低证据酒精政策(如教育和有针对性的预防),对最低单位定价(MUP)政策(政策流)的支持有限。酒业用来反对MUP的几个论点出现了,包括负面的经济影响和非法贸易。接受采访的众议员和参议员还报告说,他们与酒精行业行为者的互动比与公共卫生行为者的互动更频繁(政治流)。结论与MSA流一致,我们的研究结果表明,酒精的矛盾框架,对循证措施的弱支持以及有利于葡萄酒的政治环境可能解释了法国酒精控制政策的薄弱。未来的研究应包括更多的利益相关者,以捕捉导致政策惯性的全套动态。
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引用次数: 0
Are the data good enough? Assessing cocaine markets and indicators in The Netherlands, Denmark, and Sweden 数据足够好吗?评估荷兰、丹麦和瑞典的可卡因市场和指标
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-01-30 DOI: 10.1016/j.drugpo.2026.105176
Kim Moeller , Kamilla Haugen , Marieke Liem
The European cocaine market has undergone rapid transformations in recent years, with supply increasing and shifting geographically from southern to northwestern ports. These changes have implications for Northern Europe, as shorter distribution routes may affect prices, purity, and consumption. An unstable cocaine market may also increase risks of drug-related systemic violence.
This commentary assesses the utility of EU cocaine market indicators by examining trends in the Netherlands, Denmark and Sweden. Using data on price, purity and aggregate use reported to the European Union Drugs Agency (EUDA), we evaluate the quality and consistency of these indicators. We found that reporting for wholesale price and purity was highly inconsistent, while retail-level data were more complete, particularly from 2007 to 2023. Wastewater analysis provided a proxy for aggregate use.
Consistent with theoretical expectations, the markets in the three countries appear integrated, suggesting a supply route originating in the Netherlands and moving northward. Data deficiencies constrain research and policymaking at a time when a changing market increases risks of instability and violence.
近年来,欧洲可卡因市场发生了迅速变化,供应量增加,从地理位置上从南部港口转移到西北部港口。这些变化对北欧也有影响,因为较短的分销路线可能会影响价格、纯度和消费。不稳定的可卡因市场也可能增加与毒品有关的系统性暴力的风险。本评论通过审查荷兰、丹麦和瑞典的趋势来评估欧盟可卡因市场指标的效用。使用报告给欧盟药品管理局(EUDA)的价格、纯度和总使用量数据,我们评估了这些指标的质量和一致性。我们发现批发价格和纯度的报告高度不一致,而零售层面的数据更完整,特别是从2007年到2023年。废水分析提供了骨料利用的替代指标。与理论预期一致,这三个国家的市场似乎是一体化的,这表明一条源自荷兰并向北移动的供应路线。在不断变化的市场增加了不稳定和暴力风险之际,数据不足制约了研究和政策制定。
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引用次数: 0
Gender differences in social networks of women and men who inject drugs in Kenya 肯尼亚注射毒品的男女在社会网络中的性别差异
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-01-28 DOI: 10.1016/j.drugpo.2026.105173
Hannah N. Manley , Lindsey R. Riback , Mercy Nyakowa , Chenshu Zhang , Peter Vickerman , Jack Stone , Josephine G. Walker , Rose Wafula , Nazila Ganatra , Matthew J. Akiyama

Background

Women who inject drugs (WWID) face heightened HCV and HIV risk compared to men (MWID); yet underlying differences in social and injection networks are not well understood, particularly in resource-limited countries.

Methods

We enrolled 3152 people who inject drugs (PWID) in Kenya using respondent driven sampling. Participants were tested for HIV, HCV, and HBV, and completed a survey with behavioral and network questions. An individual’s social network members (NMs) were defined as participants they had used any drugs with and knew by name. Bivariate analyses were conducted for associations between gender, network characteristics, and injection behaviors. Multivariate logistic regressions were conducted for both men and women to examine the associations between network characteristics and disease status.

Results

About one-tenth of participants were women (9.7%, N= 306), 19.3% were HCV antibody-positive (N = 610), and 9.7% were HIV-positive (N = 306). Women were significantly more likely to be HCV antibody-positive (26.5% vs. 18.6%, p < 0.001) and HIV-positive (31.1% vs. 7.4%, p < 0.001) than men. Women were significantly more likely to have injected and had sex with people in their networks than men were (3.9% vs. 1.0%, p < 0.001). Knowledge (or lack thereof) of NM’s HIV and HCV status had significant associations with HIV and HCV positivity for both women and men.

Conclusion

Women face differential HCV- and HIV-related risk in part based upon their relationships to and behaviors with their network members. Further research examining nuances of injection and sexual relationships among women and men who inject drugs is needed. Interventions accounting for gender-based risks should also be considered.
与男性(MWID)相比,注射毒品的女性(WWID)面临更高的HCV和HIV风险;然而,社会和注射网络的潜在差异尚未得到很好的理解,特别是在资源有限的国家。方法采用受访者驱动抽样方法,在肯尼亚招募3152名注射吸毒者。研究人员对参与者进行了艾滋病毒、丙型肝炎病毒和乙型肝炎病毒检测,并完成了一项行为和网络问题的调查。一个人的社会网络成员(NMs)被定义为与他们一起使用过任何药物并知道他们的名字的参与者。对性别、网络特征和注射行为之间的关系进行了双变量分析。对男性和女性进行多变量logistic回归,以检验网络特征与疾病状态之间的关联。结果约1 / 10的参与者为女性(9.7%,N= 306), HCV抗体阳性19.3% (N = 610), hiv阳性9.7% (N = 306)。女性HCV抗体阳性(26.5% vs. 18.6%, p < 0.001)和hiv阳性(31.1% vs. 7.4%, p < 0.001)的可能性明显高于男性。女性比男性更有可能在自己的网络中注射和发生性行为(3.9% vs. 1.0%, p < 0.001)。了解(或缺乏)NM的HIV和HCV状态与女性和男性的HIV和HCV阳性显著相关。结论:女性面临不同的HCV和hiv相关风险部分取决于她们与网络成员的关系和行为。需要进一步研究注射毒品的男女之间注射和性关系的细微差别。还应考虑考虑基于性别的风险的干预措施。
{"title":"Gender differences in social networks of women and men who inject drugs in Kenya","authors":"Hannah N. Manley ,&nbsp;Lindsey R. Riback ,&nbsp;Mercy Nyakowa ,&nbsp;Chenshu Zhang ,&nbsp;Peter Vickerman ,&nbsp;Jack Stone ,&nbsp;Josephine G. Walker ,&nbsp;Rose Wafula ,&nbsp;Nazila Ganatra ,&nbsp;Matthew J. Akiyama","doi":"10.1016/j.drugpo.2026.105173","DOIUrl":"10.1016/j.drugpo.2026.105173","url":null,"abstract":"<div><h3>Background</h3><div>Women who inject drugs (WWID) face heightened HCV and HIV risk compared to men (MWID); yet underlying differences in social and injection networks are not well understood, particularly in resource-limited countries.</div></div><div><h3>Methods</h3><div>We enrolled 3152 people who inject drugs (PWID) in Kenya using respondent driven sampling. Participants were tested for HIV, HCV, and HBV, and completed a survey with behavioral and network questions. An individual’s social network members (NMs) were defined as participants they had used any drugs with and knew by name. Bivariate analyses were conducted for associations between gender, network characteristics, and injection behaviors. Multivariate logistic regressions were conducted for both men and women to examine the associations between network characteristics and disease status.</div></div><div><h3>Results</h3><div>About one-tenth of participants were women (9.7%, N= 306), 19.3% were HCV antibody-positive (<em>N</em> = 610), and 9.7% were HIV-positive (<em>N</em> = 306). Women were significantly more likely to be HCV antibody-positive (26.5% vs. 18.6%, <em>p</em> &lt; 0.001) and HIV-positive (31.1% vs. 7.4%, <em>p</em> &lt; 0.001) than men. Women were significantly more likely to have injected and had sex with people in their networks than men were (3.9% vs. 1.0%, <em>p</em> &lt; 0.001). Knowledge (or lack thereof) of NM’s HIV and HCV status had significant associations with HIV and HCV positivity for both women and men.</div></div><div><h3>Conclusion</h3><div>Women face differential HCV- and HIV-related risk in part based upon their relationships to and behaviors with their network members. Further research examining nuances of injection and sexual relationships among women and men who inject drugs is needed. Interventions accounting for gender-based risks should also be considered.</div></div>","PeriodicalId":48364,"journal":{"name":"International Journal of Drug Policy","volume":"149 ","pages":"Article 105173"},"PeriodicalIF":4.4,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Necropolitics and state-sponsored drug violence: the death penalty for drug offences in Indonesia 死亡政治和国家支持的毒品暴力:印度尼西亚对毒品犯罪的死刑
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-01-28 DOI: 10.1016/j.drugpo.2026.105157
Lucy Harry , Carolyn Hoyle

Background

Much of the literature on drug-related violence focuses on the Americas, its applicability to other regions of the world unobvious (Liem and Moeller, 2025). Focusing on the death penalty for drug offences in Indonesia – with findings generalisable to other Southeast Asian jurisdictions – we find that, while contemporary theories focus on the violence within drug markets, here the violence is unidirectional: from the state to civilians.

Methods

We apply a necropolitical theoretical framework (Mbembe, 2003) to data from interviews and focus groups with high level judges (8 participants), prosecutors (32), narcotics police (8) and other police officers (6) in Jakarta, Indonesia from 2023 to 2024.

Results

Our data reveal three key features of the necropolitical theoretical framework:
1). State of exception and siege: our participants harnessed the language of a ‘drugs emergency’ in Indonesia, with concerns about invasion, a foreign ‘insurgency’ of drugs, justifying the most punitive criminal justice response.
2). Annihilation for preservation: judicial and extrajudicial executions of drug traffickers are justified for the protection of current and future generations from the scourge of drugs.
3). Racism in post-colonial practice: executions for drug offences have been disproportionately directed at foreign nationals.

Conclusion

This paper invites the reader to zoom out from the typical focus on violence within the drug trade to consider punishment – judicial and extrajudicial – as a form of state-sponsored, necropolitical violence, part of the continuum of ‘drug-related violence’ rather than simply a matter of penal policy.
大部分关于毒品相关暴力的文献都集中在美洲,其对世界其他地区的适用性并不明显(Liem和Moeller, 2025)。关注印度尼西亚毒品犯罪的死刑——研究结果可推广到其他东南亚司法管辖区——我们发现,虽然当代理论关注的是毒品市场内部的暴力,但这里的暴力是单向的:从国家到平民。方法采用死亡政治理论框架(Mbembe, 2003)对2023年至2024年在印度尼西亚雅加达对高级法官(8名参与者)、检察官(32名参与者)、缉毒警察(8名参与者)和其他警察(6名参与者)进行访谈和焦点小组的数据进行分析。结果我们的数据揭示了死亡政治理论框架的三个关键特征:1)。例外状态和围困:我们的参与者利用印度尼西亚“毒品紧急状态”的语言,关注入侵,外国毒品“叛乱”,为最具惩罚性的刑事司法反应辩护2)。3)为保存而消灭:为了保护今世后代不受毒品祸害之害,有理由对毒品贩运者进行司法和法外处决。后殖民实践中的种族主义:对毒品犯罪的处决不成比例地针对外国人。本文邀请读者从对毒品贸易中的暴力的典型关注中拉远,将惩罚——司法和法外惩罚——视为一种国家支持的、死亡政治暴力的形式,是“与毒品有关的暴力”连续体的一部分,而不仅仅是刑事政策的问题。
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引用次数: 0
Pipes as an engagement tool: qualitative findings from a crack equipment and harm reduction training intervention in England 管材作为一种参与工具:从裂缝设备和减少伤害培训干预在英格兰的定性发现
IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE Pub Date : 2026-01-28 DOI: 10.1016/j.drugpo.2026.105165
Casey Sharpe , Joanna Busza , Cedomir Vuckovic , Jenny Scott , Vivian Hope , Mat Southwell , Louise Wilkins , Lucy Platt , Magdalena Harris

Background

Crack cocaine use is increasingly prevalent in England, yet drug services are poorly equipped to support the needs of this population. Provision of stimulant inhalation equipment is prohibited, and workforce crack-related harm reduction knowledge is generally low. The Safe Inhalation Pipe Provision (SIPP) project piloted a crack inhalation equipment and training intervention in England. This paper explores how and in what way crack training and equipment provision influences engagement with drug service providers.

Methods

SIPP is a mixed-method study, comprising a before-and-after survey, service monitoring data, qualitative interviews, focus groups, and observations. Here we report qualitative data generated with people who use crack and providers at three intervention and three comparison group sites. We conducted a thematic analysis and report themes specific to contact and engagement with drug services.

Results

Prior to intervention implementation, little adequate crack-specific support was identified. SIPP equipment provision facilitated increased contact and/or disclosure of crack use with services. Workforce training enhanced communication and relationship-building opportunities, enabling disclosure of additional need and commensurate provision or linkage to health and social supports. The capacity for contact to facilitate engagement was impacted by organisational and structural constraints, and for some populations barriers to access remain entrenched.

Conclusions

Provision of crack inhalation equipment can facilitate new contacts with services among a highly marginalised population. Complementary workforce training helps to enable relationship building and engagement opportunity. Additional methods of provision, including through peer networks, are required to support people for whom barriers to service access remain.

Trial registration

ISRCTN12541454 https://doi.org/10.1186/ISRCTN12541454
快克可卡因的使用在英国越来越普遍,然而毒品服务机构却无法满足这一人群的需求。禁止提供兴奋剂吸入设备,员工对减少裂缝危害的知识普遍较低。安全吸入管规定(SIPP)项目试点裂纹吸入设备和培训干预在英格兰。本文探讨如何以及以何种方式破解培训和设备提供影响与药物服务提供者的参与。方法sipp是一项混合方法研究,包括前后调查、服务监测数据、定性访谈、焦点小组和观察。在这里,我们报告定性数据产生的人谁使用裂缝和提供者在三个干预和三个比较组网站。我们进行了专题分析,并报告了与药物服务接触和参与有关的具体主题。结果在实施干预之前,很少有足够的针对裂缝的支持。SIPP设备的提供有助于增加与服务部门的联系和/或披露裂缝使用情况。劳动力培训增加了沟通和建立关系的机会,使人们能够披露额外的需求,并提供相应的保健和社会支持或与之联系。促进接触的接触能力受到组织和结构限制的影响,对一些人群来说,接触的障碍仍然根深蒂固。结论提供裂纹吸入设备可以促进高度边缘化人群与服务机构的新接触。互补的劳动力培训有助于建立关系和参与机会。需要其他的提供方法,包括通过对等网络,来支持那些在获得服务方面仍然存在障碍的人。试验注册isrctn12541454 https://doi.org/10.1186/ISRCTN12541454
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引用次数: 0
期刊
International Journal of Drug Policy
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