Perioperative intravenous lidocaine infusion for postsurgical pain management in bariatric surgery patients.

Gilberto Duarte-Medrano, Natalia Nuño-Lámbarri, Analucia Dominguez-Franco, Yazmin Lopez-Rodriguez, Marissa Minutti-Palacios, Adrian Palacios-Chavarria, Luigi La Via, Daniele Salvatore Paternò, Giovanni Misseri, Giuseppe Cuttone, Massimiliano Sorbello, Guillermo Dominguez-Cherit, Diego Escarramán
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Abstract

Introduction: Obesity is one of the biggest modern health issues worldwide. Owing to the failure of both behavioral and pharmacological measures, the surgical approach has been established as the main conduct to follow, with bariatric surgery being one of the most effective and safe procedures. One of the bases for the optimal analgesic strategy is the use of adjuvants during the perioperative period. One of the main drugs in use is lidocaine.

Aim: To evaluate postoperative pain after perioperative lidocaine infusion in patients undergoing bariatric surgery and describe the presence of nausea and vomiting during the first 24 h.

Methods: This was a retrospective study of patients who underwent laparoscopic bariatric surgery at ABC Medical Center. Two study arms were established: a group of patients who received lidocaine infusion and a control group. The presence of pain, nausea, or vomiting was evaluated upon admission to the recovery area and 1 h and 24 h after the intervention. The normal distribution of the data was first verified via the Shapiro-Wilk test. The data are presented as medians for quantitative variables and as frequencies for qualitative variables.

Results: A total of 50 surgeries were performed, with a significant correlation between lidocaine infusion and lower pain values at 1 h (p = 0.04). Similarly, there was a marked trend in the presence of nausea in control group 4 (18.6%) vs. 15 (53.5%).

Conclusions: Our data suggest that the use of intraoperative lidocaine infusion is limited in postoperative pain management; nonetheless, it significantly improves the incidence of postoperative nausea.

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减肥手术患者围手术期静脉注射利多卡因治疗术后疼痛。
引言肥胖症是全球最大的现代健康问题之一。由于行为疗法和药物疗法均告失败,手术疗法已被确定为主要的治疗方法,而减肥手术是最有效、最安全的手术之一。最佳镇痛策略的基础之一是在围手术期使用辅助药物。目的:评估减肥手术患者围手术期输注利多卡因后的术后疼痛,并描述头 24 小时内是否出现恶心和呕吐:这是一项回顾性研究,对象是在ABC医疗中心接受腹腔镜减肥手术的患者。研究分为两组:利多卡因输注组和对照组。研究人员在患者入院时、手术后 1 小时和 24 小时对其是否出现疼痛、恶心或呕吐进行了评估。数据的正态分布首先通过 Shapiro-Wilk 检验进行验证。定量变量的数据以中位数表示,定性变量的数据以频率表示:共进行了 50 例手术,利多卡因输注与 1 小时后疼痛值降低之间存在显著相关性(p = 0.04)。同样,对照组 4 例(18.6%)与对照组 15 例(53.5%)相比,出现恶心的趋势明显:我们的数据表明,术中利多卡因输注在术后疼痛治疗中的应用有限,但它能显著改善术后恶心的发生率。
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