Association among raised intraventricular pressure, clinical signs, and magnetic resonance imaging findings in dogs with congenital internal hydrocephalus.

IF 2.6 2区 农林科学 Journal of Veterinary Internal Medicine Pub Date : 2024-10-31 DOI:10.1111/jvim.17235
Daniela Farke, Agnieszka Olszewska, Kathrin Büttner, Martin J Schmidt
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Abstract

Background: Dogs with internal hydrocephalus do not necessarily have high intraventricular pressure (IVP).

Hypothesis/objectives: Not all reported MRI findings indicate high IVP and some clinical signs might be associated with elevated IVP and syringomyelia.

Animals: Fifty-three dogs.

Materials and methods: Cross-sectional study. Clinical signs and MRI findings were evaluated for an association of IVP >12 mm Hg and syringomyelia.

Results: High IVP was associated with obtundation OR 4.64 (95% CI 1.27-16.93) (P = .02), head tilt OR 6.42 (95% CI 1.08-37.97) (P = .04) and nystagmus OR 8.24 (95% CI 1.44-47.07) (P = .02). Pain was associated with syringomyelia OR 3.4 (95% CI 0.98-11.78) (P = .05). The number of affected ventricles was associated with high IVP OR 2.85 (95% CI 0.97-8.33) (P = .05) and syringomyelia OR 12.74 (95% CI 2.93-55.4) (P = .0007). Periventricular edema OR 24.46 (95% CI 4.54-131.77), OR 7.61 (95% CI 1.91-30.32) (P < .0002, P = .004) and signal void sign OR 17.34 (95% CI 4.01-74.95), OR 4.18 (95% CI 1.16-15.02) (P < .0001, P = .03) were associated with high IVP and syringomyelia. The probability for syringomyelia is lower with disruption of the internal capsule OR 0.19 (95% CI 0.05-0.72) (P = .01) and higher VBR OR 0.25 (95% CI 0.1-0.63) (P = .004).

Conclusions and clinical importance: Previously reported MRI findings are not predictive of high IVP. Clinical signs and MRI findings should be used to make a diagnosis of internal hydrocephalus in dogs with or without high IVP.

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先天性内脑积水患犬脑室内压升高、临床症状和磁共振成像结果之间的关联。
背景:患有内脑积水的狗并不一定具有高脑室内压(IVP):并非所有报告的 MRI 结果都表明 IVP 偏高,一些临床症状可能与 IVP 升高和鞘膜积液有关:材料和方法:横断面研究:横断面研究。对临床症状和磁共振成像结果进行评估,以确定 IVP >12 mm Hg 与鞘膜积液是否相关:高 IVP 与昏迷 OR 4.64 (95% CI 1.27-16.93) (P = .02)、头部倾斜 OR 6.42 (95% CI 1.08-37.97) (P = .04) 和眼球震颤 OR 8.24 (95% CI 1.44-47.07) (P = .02) 相关。疼痛与鞘膜积液 OR 3.4 (95% CI 0.98-11.78) (P = .05) 相关。受影响脑室的数量与高 IVP OR 2.85 (95% CI 0.97-8.33) (P = .05) 和鞘膜积液 OR 12.74 (95% CI 2.93-55.4) (P = .0007) 相关。脑室周围水肿 OR 24.46(95% CI 4.54-131.77),OR 7.61(95% CI 1.91-30.32)(P 结论和临床重要性:之前报道的磁共振成像结果不能预测高IVP。临床症状和 MRI 检查结果应用于诊断有或没有高 IVP 的犬的内脑积水。
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来源期刊
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine Veterinary-General Veterinary
自引率
11.50%
发文量
243
期刊介绍: The mission of the Journal of Veterinary Internal Medicine is to advance veterinary medical knowledge and improve the lives of animals by publication of authoritative scientific articles of animal diseases.
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