Association among raised intraventricular pressure, clinical signs, and magnetic resonance imaging findings in dogs with congenital internal hydrocephalus.

IF 2.6 2区 农林科学 Journal of Veterinary Internal Medicine Pub Date : 2024-10-31 DOI:10.1111/jvim.17235
Daniela Farke, Agnieszka Olszewska, Kathrin Büttner, Martin J Schmidt
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Abstract

Background: Dogs with internal hydrocephalus do not necessarily have high intraventricular pressure (IVP).

Hypothesis/objectives: Not all reported MRI findings indicate high IVP and some clinical signs might be associated with elevated IVP and syringomyelia.

Animals: Fifty-three dogs.

Materials and methods: Cross-sectional study. Clinical signs and MRI findings were evaluated for an association of IVP >12 mm Hg and syringomyelia.

Results: High IVP was associated with obtundation OR 4.64 (95% CI 1.27-16.93) (P = .02), head tilt OR 6.42 (95% CI 1.08-37.97) (P = .04) and nystagmus OR 8.24 (95% CI 1.44-47.07) (P = .02). Pain was associated with syringomyelia OR 3.4 (95% CI 0.98-11.78) (P = .05). The number of affected ventricles was associated with high IVP OR 2.85 (95% CI 0.97-8.33) (P = .05) and syringomyelia OR 12.74 (95% CI 2.93-55.4) (P = .0007). Periventricular edema OR 24.46 (95% CI 4.54-131.77), OR 7.61 (95% CI 1.91-30.32) (P < .0002, P = .004) and signal void sign OR 17.34 (95% CI 4.01-74.95), OR 4.18 (95% CI 1.16-15.02) (P < .0001, P = .03) were associated with high IVP and syringomyelia. The probability for syringomyelia is lower with disruption of the internal capsule OR 0.19 (95% CI 0.05-0.72) (P = .01) and higher VBR OR 0.25 (95% CI 0.1-0.63) (P = .004).

Conclusions and clinical importance: Previously reported MRI findings are not predictive of high IVP. Clinical signs and MRI findings should be used to make a diagnosis of internal hydrocephalus in dogs with or without high IVP.

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先天性内脑积水患犬脑室内压升高、临床症状和磁共振成像结果之间的关联。
背景:患有内脑积水的狗并不一定具有高脑室内压(IVP):并非所有报告的 MRI 结果都表明 IVP 偏高,一些临床症状可能与 IVP 升高和鞘膜积液有关:材料和方法:横断面研究:横断面研究。对临床症状和磁共振成像结果进行评估,以确定 IVP >12 mm Hg 与鞘膜积液是否相关:高 IVP 与昏迷 OR 4.64 (95% CI 1.27-16.93) (P = .02)、头部倾斜 OR 6.42 (95% CI 1.08-37.97) (P = .04) 和眼球震颤 OR 8.24 (95% CI 1.44-47.07) (P = .02) 相关。疼痛与鞘膜积液 OR 3.4 (95% CI 0.98-11.78) (P = .05) 相关。受影响脑室的数量与高 IVP OR 2.85 (95% CI 0.97-8.33) (P = .05) 和鞘膜积液 OR 12.74 (95% CI 2.93-55.4) (P = .0007) 相关。脑室周围水肿 OR 24.46(95% CI 4.54-131.77),OR 7.61(95% CI 1.91-30.32)(P 结论和临床重要性:之前报道的磁共振成像结果不能预测高IVP。临床症状和 MRI 检查结果应用于诊断有或没有高 IVP 的犬的内脑积水。
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来源期刊
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine Veterinary-General Veterinary
自引率
11.50%
发文量
243
期刊介绍: The mission of the Journal of Veterinary Internal Medicine is to advance veterinary medical knowledge and improve the lives of animals by publication of authoritative scientific articles of animal diseases.
期刊最新文献
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