Quantitative MRI in Childhood Neuroblastoma: Beyond the Assessment of Image-defined Risk Factors.

IF 5.6 Q1 ONCOLOGY Radiology. Imaging cancer Pub Date : 2024-11-01 DOI:10.1148/rycan.240089
Haoru Wang, Jinhua Cai
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Abstract

Neuroblastoma commonly occurs in children. MRI is a radiation-free imaging modality and has played an important role in identifying image-defined risk factors of neuroblastoma, providing necessary guidance for surgical resection and treatment response evaluation. However, image-defined risk factors are limited to providing structural information about neuroblastoma. With the evolution of MRI technologies, quantitative MRI can not only help assess image-defined risk factors but can also quantitatively reflect the biologic features of neuroblastoma in a noninvasive manner. Therefore, compared with anatomic imaging, these emerging quantitative MRI technologies are expected to provide more imaging biomarkers for the management of neuroblastoma. This review article discusses the current applications of quantitative MRI technologies in evaluating childhood neuroblastoma. Keywords: Pediatrics, MR-Functional Imaging, Children, MRI, Neuroblastoma, Quantitative Imaging © RSNA, 2024.

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儿童神经母细胞瘤的定量 MRI:超越图像定义的风险因素评估。
神经母细胞瘤常见于儿童。磁共振成像是一种无辐射成像模式,在确定神经母细胞瘤的图像定义风险因素方面发挥了重要作用,为手术切除和治疗反应评估提供了必要的指导。然而,图像定义的危险因素仅限于提供神经母细胞瘤的结构信息。随着核磁共振成像技术的发展,定量核磁共振成像不仅可以帮助评估图像定义的危险因素,还能以无创方式定量反映神经母细胞瘤的生物特征。因此,与解剖成像相比,这些新兴的定量 MRI 技术有望为神经母细胞瘤的治疗提供更多的成像生物标志物。这篇综述文章讨论了目前定量磁共振成像技术在评估儿童神经母细胞瘤中的应用。关键词儿科 MR-功能成像 儿童 MRI 神经母细胞瘤 定量成像 © RSNA, 2024.
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